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CC (cat)
CC, for "CopyCat" ''or'' "Carbon Copy" (December 22, 2001 – March 3, 2020), was a brown tabby and white domestic shorthair and the first cloned pet. She was cloned by scientists at Texas A&M University in conjunction with Genetic Savings & Clone Inc. CC's surrogate mother was a tabby, but her genetic donor, Rainbow, was a calico domestic shorthair. The difference in hair coloration between CC and Rainbow is due to X-inactivation and epigenetic re-programming, which normally occurs in a fertilized embryo before implantation. In September 2006, CC gave birth to four kittens. The litter was fathered naturally by another lab cat named Smokey. It included two males named Tim and Zip and one female named Tess. Another kitten (a female) was stillborn. This incident was the first time a cloned pet gave birth. Throughout her life, CC appeared to be free of the cloning-related health problems that have arisen in some other animal clones. "CC has always been a perfectly normal cat ...
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College Station, Texas
College Station is a city in Brazos County, Texas, situated in East-Central Texas in the heart of the Brazos Valley, towards the eastern edge of the region known as the Texas Triangle. It is northwest of Houston and east-northeast of Austin. As of the 2020 census, College Station had a population of 120,511. College Station and Bryan make up the Bryan-College Station metropolitan area, the 13th-largest metropolitan area in Texas with 273,101 people as of 2019. College Station is home to the main campus of Texas A&M University, the flagship institution of the Texas A&M University System. The city owes its name and existence to the university's location along a railroad. Texas A&M's triple designation as a Land-, Sea-, and Space-Grant institution reflects the broad scope of the research endeavors it brings to the city, with ongoing projects funded by agencies such as NASA, the National Institutes of Health, the National Science Foundation, and the Office of Naval Research. ...
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Reprogramming
In biology, reprogramming refers to erasure and remodeling of epigenetic marks, such as DNA methylation, during mammalian development or in cell culture. Such control is also often associated with alternative covalent modifications of histones. Reprogrammings that are both large scale (10% to 100% of epigenetic marks) and rapid (hours to a few days) occur at three life stages of mammals. Almost 100% of epigenetic marks are reprogrammed in two short periods early in development after fertilization of an ovum by a sperm. In addition, almost 10% of DNA methylations in neurons of the hippocampus can be rapidly altered during formation of a strong fear memory. After fertilization in mammals, DNA methylation patterns are largely erased and then re-established during early embryonic development. Almost all of the methylations from the parents are erased, first during early embryogenesis, and again in gametogenesis, with demethylation and remethylation occurring each time. Demethyla ...
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Cloned Cats
Cloning is the process of producing individual organisms with identical or virtually identical DNA, either by natural or artificial means. In nature, some organisms produce clones through asexual reproduction. In the field of biotechnology, cloning is the process of creating cloned organisms (copies) of cells and of DNA fragments (molecular cloning). Etymology Coined by Herbert J. Webber, the term clone derives from the Ancient Greek word (), ''twig'', which is the process whereby a new plant is created from a twig. In botany, the term ''lusus'' was used. In horticulture, the spelling ''clon'' was used until the early twentieth century; the final ''e'' came into use to indicate the vowel is a "long o" instead of a "short o". Since the term entered the popular lexicon in a more general context, the spelling ''clone'' has been used exclusively. Natural cloning Cloning is a natural form of reproduction that has allowed life forms to spread for hundreds of millions of years. It ...
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2001 In Science
The year 2001 in science and technology involved many events, some of which are included below. Astronomy and space exploration * February 12 – The ''NEAR Shoemaker'' spacecraft lands in the "saddle" region of 433 Eros, becoming the first spacecraft to land on an asteroid. * June 21 – Solar eclipse of June 21, 2001, a total eclipse. * August 8 – NASA's ''Genesis'' spacecraft is launched. * October 15 – NASA's '' Galileo'' spacecraft passes within 112 miles (180 km) of Jupiter's moon Io. * November 27 – The Hubble Space Telescope detects sodium in the atmosphere of HD 209458 b, the first exoplanet atmosphere to be measured. * December 14 – Solar eclipse of December 14, 2001, an annular eclipse. Biology * January 8 – The first animal from an endangered species produced by cloning, a gaur named Noah, is born at Trans Ova Genetics in Sioux Center, Iowa. He dies within 48 hours of a common dysentery. * January – The second animal from an endangered species p ...
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List Of Individual Cats
This is a list of famous cats which achieved some degree of popularity either in their own right or by association with someone famous. Before the modern era * Nedjem or Nojem (Egyptian: ''nḏm'' "Sweet One" or "Sweetie"), 15th century BC. The cat of Puimre, second priest of Amun during the reign of Queen Hatshepsut. Depicted on a damaged relief from Puimre's tomb, Nedjem is the earliest known cat to bear an individual name. *Pangur Bán (Old Irish "White Pangur"; the meaning of the latter word is unclear), 8th-9th century AD. The cat of an otherwise unknown Irish monk, who wrote a poem cataloguing the similarities between the cat's character and his own. * Ta-Miu (Egyptian: ''tꜣ mjw'' "She-Cat"), 14th century BC. The cat of Crown Prince Thutmose, mummified after her death and buried in a decorated sarcophagus in Prince Thutmose's own tomb following his own early demise. * Muezza, 7th century AD. The (possibly apocryphal) cat of the Islamic prophet Muhammad. Famous in own rig ...
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Pet Cloning
Commercial animal cloning is the cloning of animals for commercial purposes, currently, including livestock, competition camels and horses, pets, medical uses, endangered and extinct animals, as first demonstrated in 1996 for Dolly the sheep. Cloning methods Moving or copying all (or nearly all) genes from one animal to form a second, genetically nearly identical, animal is usually done through one of three methods: the Roslin technique, the Honolulu technique, and Artificial Twinning. The first two of these involve a process known as somatic cell nuclear transfer. In this process, an oocyte is taken from a surrogate mother and put through enucleation, a process that removes the nucleus from inside the oocyte. Somatic cells are then taken from the animal that is being cloned, transferred into the blank oocyte in order to provide genetic material, and fused with the oocyte using an electrical current. The oocyte is then activated and re-inserted into the surrogate mother. The end ...
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Little Nicky (cat)
Little Nicky (born October 17, 2004) is the first commercially produced clone of a cat. He was produced from the DNA of a 17-year-old Maine Coon cat named Nicky who died in 2003. Little Nicky's owner, a north Texas woman named Julie (whose last name was not released) paid $50,000 to have Nicky cloned. Little Nicky's owner reported that the cat shared many characteristics with his predecessor, including a similar personality and appearance. Origin and Cloning The cloning of Little Nicky was performed by the California-based company Genetic Savings & Clone, which later closed in 2006. This followed the first successful cloning of a cat by the company in conjunction with Texas A&M University. The cloning was performed by the chromatin transfer technique, a variant of nuclear transfer. The cloning of Little Nicky was a result of an offer by the company called the "Nine Lives Extravaganza" launched in 2004. Ethical controversy Groups such as the Humane Society of the United States, ...
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Maine Coon
The Maine Coon is a large domesticated cat breed. It is one of the oldest natural breeds in North America. The breed originated in the U.S. state of Maine, where it is the official state cat. The breed was popular in cat shows in the late 19th century, but its existence became threatened when long-haired breeds from overseas were introduced in the early 20th century. The Maine Coon has since made a comeback and is now the third most popular pedigreed cat breed in the world. The Maine Coon is a large and social cat, which could be the reason why it has a reputation of being referred to as "the gentle giant." The Maine Coon is predominantly known for its size and dense coat of fur which helps the large feline to survive in the harsh climate of Maine, the state from which they originated. The Maine Coon is often cited as having " dog-like" characteristics. Due to the large size of this feline, professionals have noticed certain health problems arising in the breed, including fel ...
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Kitten
A kitten is a juvenile cat. After being born, kittens display primary altriciality and are totally dependent on their mothers for survival. They normally do not open their eyes for seven to ten days. After about two weeks, kittens develop quickly and begin to explore the world outside their nest. After a further three to four weeks, they begin to eat solid food and grow baby teeth. Domestic kittens are highly social animals and usually enjoy human companionship. Etymology The word "kitten" derives from the Middle English word , which in turn came from the Old French or . Juvenile big cats are called "cubs" rather than kittens; either term (but usually more commonly "kitten") may be used for the young of smaller wild felids, such as ocelots, caracals, and lynxes. Development A feline litter usually consists of two to five kittens, but litters with one to more than ten are known. Kittens are typically born after a gestation lasting between 64 and 67 days, with an average l ...
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Embryo
An embryo is an initial stage of development of a multicellular organism. In organisms that reproduce sexually, embryonic development is the part of the life cycle that begins just after fertilization of the female egg cell by the male sperm cell. The resulting fusion of these two cells produces a single-celled zygote that undergoes many cell divisions that produce cells known as blastomeres. The blastomeres are arranged as a solid ball that when reaching a certain size, called a morula, takes in fluid to create a cavity called a blastocoel. The structure is then termed a blastula, or a blastocyst in mammals. The mammalian blastocyst hatches before implantating into the endometrial lining of the womb. Once implanted the embryo will continue its development through the next stages of gastrulation, neurulation, and organogenesis. Gastrulation is the formation of the three germ layers that will form all of the different parts of the body. Neurulation forms the nervous ...
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Fertilisation
Fertilisation or fertilization (see spelling differences), also known as generative fertilisation, syngamy and impregnation, is the fusion of gametes to give rise to a new individual organism or offspring and initiate its development. Processes such as insemination or pollination which happen before the fusion of gametes are also sometimes informally called fertilisation. The cycle of fertilisation and development of new individuals is called sexual reproduction. During double fertilisation in angiosperms the haploid male gamete combines with two haploid polar nuclei to form a triploid primary endosperm nucleus by the process of vegetative fertilisation. History In Antiquity, Aristotle conceived the formation of new individuals through fusion of male and female fluids, with form and function emerging gradually, in a mode called by him as epigenetic. In 1784, Spallanzani established the need of interaction between the female's ovum and male's sperm to form a zygote in frog ...
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Epigenetics
In biology, epigenetics is the study of stable phenotypic changes (known as ''marks'') that do not involve alterations in the DNA sequence. The Greek prefix '' epi-'' ( "over, outside of, around") in ''epigenetics'' implies features that are "on top of" or "in addition to" the traditional genetic basis for inheritance. Epigenetics most often involves changes that affect the regulation of gene expression, but the term can also be used to describe any heritable phenotypic change. Such effects on cellular and physiological phenotypic traits may result from external or environmental factors, or be part of normal development. The term also refers to the mechanism of changes: functionally relevant alterations to the genome that do not involve mutation of the nucleotide sequence. Examples of mechanisms that produce such changes are DNA methylation and histone modification, each of which alters how genes are expressed without altering the underlying DNA sequence. Gene expression c ...
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