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Broca's Area
Broca's area, or the Broca area (, also , ), is a region in the frontal lobe of the dominant hemisphere, usually the left, of the brain with functions linked to speech production. Language processing has been linked to Broca's area since Pierre Paul Broca reported impairments in two patients. They had lost the ability to speak after injury to the posterior inferior frontal gyrus (pars triangularis) (BA45) of the brain. Since then, the approximate region he identified has become known as Broca's area, and the deficit in language production as Broca's aphasia, also called expressive aphasia. Broca's area is now typically defined in terms of the pars opercularis and pars triangularis of the inferior frontal gyrus, represented in Brodmann's cytoarchitectonic map as Brodmann area 44 and Brodmann area 45 of the dominant hemisphere. Functional magnetic resonance imaging (fMRI) has shown language processing to also involve the third part of the inferior frontal gyrus the pars or ...
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Brodmann Area 44
Brodmann area 44, or BA44, is part of the frontal Front may refer to: Arts, entertainment, and media Films * ''The Front'' (1943 film), a 1943 Soviet drama film * ''The Front'', 1976 film Music *The Front (band), an American rock band signed to Columbia Records and active in the 1980s and ea ... cerebral cortex, cortex in the human brain. Situated just anterior to premotor cortex (Brodmann area 6, BA6) and on the lateral surface, inferior to Brodmann area 9, BA9. This area is also known as pars opercularis (of the inferior frontal gyrus), and it refers to a subdivision of the cytoarchitecture, cytoarchitecturally defined frontal region of cerebral cortex. In the human it corresponds approximately to the Inferior frontal gyrus#Structure, opercular part of the inferior frontal gyrus. Thus, it is bounded caudally by the inferior precentral sulcus (H) and rostrally by the anterior ascending limb of lateral sulcus (H). It surrounds the diagonal sulcus (H). In the depth of the la ...
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Pars Opercularis
The inferior frontal gyrus (IFG), (gyrus frontalis inferior), is the lowest positioned gyrus of the frontal gyri, of the frontal lobe, and is part of the prefrontal cortex. Its superior border is the inferior frontal sulcus (which divides it from the middle frontal gyrus), its inferior border is the lateral sulcus (which divides it from the superior temporal gyrus) and its posterior border is the inferior precentral sulcus. Above it is the middle frontal gyrus, behind it is the precentral gyrus. The inferior frontal gyrus contains Broca's area, which is involved in language processing and speech production. Structure The inferior frontal gyrus is highly convoluted and has three cytoarchitecturally diverse regions. The three subdivisions are an opercular part, a triangular part, and an orbital part. These divisions are marked by two rami arising from the lateral sulcus. The ascending ramus separates the opercular and triangular parts. The anterior (horizontal) ramus separates ...
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Talairach Coordinates
Talairach coordinates, also known as Talairach space, is a 3-dimensional coordinate system (known as an 'atlas') of the human brain, which is used to map the location of brain structures independent from individual differences in the size and overall shape of the brain. It is still common to use Talairach coordinates in functional brain imaging studies and to target transcranial stimulation of brain regions. However, alternative methods such as the MNI Coordinate System (originated at the Montreal Neurological Institute and Hospital) have largely replaced Talairach for stereotaxy and other procedures. History The coordinate system was first created by neurosurgeons Jean Talairach and Gabor Szikla in their work on the ''Talairach Atlas'' in 1967, creating a standardized grid for neurosurgery. The grid was based on the idea that distances to lesions in the brain are proportional to overall brain size (i.e., the distance between two structures is larger in a larger brain). In 1988 a ...
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Sulcus (neuroanatomy)
In neuroanatomy, a sulcus (Latin: "furrow", pl. ''sulci'') is a depression or groove in the cerebral cortex. It surrounds a gyrus (pl. gyri), creating the characteristic folded appearance of the brain in humans and other mammals. The larger sulci are usually called fissures. Structure Sulci, the grooves, and gyri, the folds or ridges, make up the folded surface of the cerebral cortex. Larger or deeper sulci are termed fissures, and in many cases the two terms are interchangeable. The folded cortex creates a larger surface area for the brain in humans and other mammals. When looking at the human brain, two-thirds of the surface are hidden in the grooves. The sulci and fissures are both grooves in the cortex, but they are differentiated by size. A sulcus is a shallower groove that surrounds a gyrus. A fissure is a large furrow that divides the brain into lobes and also into the two hemispheres as the longitudinal fissure. Importance of expanded surface area As the sur ...
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Topography
Topography is the study of the forms and features of land surfaces. The topography of an area may refer to the land forms and features themselves, or a description or depiction in maps. Topography is a field of geoscience and planetary science and is concerned with local detail in general, including not only relief, but also natural, artificial, and cultural features such as roads, land boundaries, and buildings. In the United States, topography often means specifically ''relief'', even though the USGS topographic maps record not just elevation contours, but also roads, populated places, structures, land boundaries, and so on. Topography in a narrow sense involves the recording of relief or terrain, the three-dimensional quality of the surface, and the identification of specific landforms; this is also known as geomorphometry. In modern usage, this involves generation of elevation data in digital form (DEM). It is often considered to include the graphic representat ...
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Brodmann Cytoarchitectonics 45
Brodmann is a German surname. Notable people with the surname include: * Ines Brodmann (birth date unknown), Swiss orienteer *Korbinian Brodmann (1868–1918), German neurologist * Mario Brodmann (born 1966), Swiss former ice hockey forward * René Brodmann (born 1933), Swiss football defender See also *Brodmann area, a region in the brain cortex *Michael L. Brodman Michael L. Brodman is an American gynecologist and obstetrician and currently the Ellen and Howard C. Katz Professor and Chairman of the Department of Obstetrics, Gynecology and Reproductive Science at Mount Sinai Hospital, Mount Sinai Health ..., American gynecologist and obstetrician {{surname, Brodmann German-language surnames ...
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Brodmann Cytoarchitectonics 44
Brodmann is a German surname. Notable people with the surname include: * Ines Brodmann (birth date unknown), Swiss orienteer *Korbinian Brodmann (1868–1918), German neurologist * Mario Brodmann (born 1966), Swiss former ice hockey forward * René Brodmann (born 1933), Swiss football defender See also *Brodmann area, a region in the brain cortex *Michael L. Brodman Michael L. Brodman is an American gynecologist and obstetrician and currently the Ellen and Howard C. Katz Professor and Chairman of the Department of Obstetrics, Gynecology and Reproductive Science at Mount Sinai Hospital, Mount Sinai Health ..., American gynecologist and obstetrician {{surname, Brodmann German-language surnames ...
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Brain Tumor
A brain tumor occurs when abnormal cells form within the brain. There are two main types of tumors: malignant tumors and benign (non-cancerous) tumors. These can be further classified as primary tumors, which start within the brain, and secondary tumors, which most commonly have spread from tumors located outside the brain, known as brain metastasis tumors. All types of brain tumors may produce symptoms that vary depending on the size of the tumor and the part of the brain that is involved. Where symptoms exist, they may include headaches, seizures, problems with vision, vomiting and mental changes. Other symptoms may include difficulty walking, speaking, with sensations, or unconsciousness. The cause of most brain tumors is unknown. Uncommon risk factors include exposure to vinyl chloride, Epstein–Barr virus, ionizing radiation, and inherited syndromes such as neurofibromatosis, tuberous sclerosis, and von Hippel-Lindau Disease. Studies on Mobile phone radiation and h ...
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Brodmann Area 6
Brodmann area 6 (BA6) is part of the frontal cortex in the human brain. Situated just anterior to the primary motor cortex ( BA4), it is composed of the premotor cortex and, medially, the supplementary motor area (SMA). This large area of the frontal cortex is believed to play a role in planning complex, coordinated movements. Brodmann area 6 is also called agranular frontal area 6 in humans because it lacks an internal granular cortical layer (layer IV). It is a subdivision of the cytoarchitecturally defined precentral region of cerebral cortex. In the human brain, it is located on the portions of the precentral gyrus that are not occupied by Brodmann area 4; furthermore, BA6 extends onto the caudal portions of the superior frontal and middle frontal gyri. It extends from the cingulate sulcus on the medial aspect of the hemisphere to the lateral sulcus on the lateral aspect. It is bounded rostrally by the granular frontal region and caudally by the gigantopyramidal area 4 (B ...
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Orbital Part Of Inferior Frontal Gyrus
The orbital part of inferior frontal gyrus also known as the pars orbitalis is the orbital part of the inferior frontal gyrus. In humans, this region is bordered by the triangular part of the inferior frontal gyrus (pars triangularis) and, surrounding the anterior horizontal limb of the lateral sulcus, a portion of the opercular part of inferior frontal gyrus (pars opercularis). Bounded caudally by the anterior ascending limb of the lateral sulcus, it borders on the insula in the depth of the lateral sulcus. It is bordered anteriorly/inferiorly by the lateral orbital sulcus. Cytoarchitectonically it is most closely represented by Brodmann area 47 (BA47).Brodmann, K. (1909). Vergleichende Lokalisationslehre der Grosshirnrinde in ihren Prinzipien dargestellt auf Grund des Zellenbaues. Leipzig, Germany: Barth. However, BA47 and pars orbitalis are not synonymous, as pars orbitalis specifically refers to a grossly visible gyral region and BA47 refers to the cytoarchitectonic fea ...
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Functional Magnetic Resonance Imaging
Functional magnetic resonance imaging or functional MRI (fMRI) measures brain activity by detecting changes associated with blood flow. This technique relies on the fact that cerebral blood flow and neuronal activation are coupled. When an area of the brain is in use, blood flow to that region also increases. The primary form of fMRI uses the blood-oxygen-level dependent (BOLD) contrast, discovered by Seiji Ogawa in 1990. This is a type of specialized brain and body scan used to map neural activity in the brain or spinal cord of humans or other animals by imaging the change in blood flow (hemodynamic response) related to energy use by brain cells. Since the early 1990s, fMRI has come to dominate brain mapping research because it does not involve the use of injections, surgery, the ingestion of substances, or exposure to ionizing radiation. This measure is frequently corrupted by noise from various sources; hence, statistical procedures are used to extract the underlying signal. ...
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Brodmann Area
A Brodmann area is a region of the cerebral cortex, in the human or other primate brain, defined by its cytoarchitecture, or histological structure and organization of cells. History Brodmann areas were originally defined and numbered by the German anatomist Korbinian Brodmann based on the cytoarchitectural organization of neurons he observed in the cerebral cortex using the Nissl method of cell staining. Brodmann published his maps of cortical areas in humans, monkeys, and other species in 1909, along with many other findings and observations regarding the general cell types and laminar organization of the mammalian cortex. The same Brodmann area number in different species does not necessarily indicate homologous areas. A similar, but more detailed cortical map was published by Constantin von Economo and Georg N. Koskinas in 1925. Present importance Brodmann areas have been discussed, debated, refined, and renamed exhaustively for nearly a century and remain the most w ...
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