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Brendan Frey
Brendan John Frey FRSC (born 29 August 1968) is a Canadian-born entrepreneur, engineer and scientist. He is Founder and CEO of Deep Genomics, Cofounder of the Vector Institute for Artificial Intelligence and Professor of Engineering and Medicine at the University of Toronto. Frey is a pioneer in the development of machine learning and artificial intelligence methods, their use in accurately determining the consequences of genetic mutations, and in designing medications that can slow, stop or reverse the progression of disease. As far back as 1995, Frey co-invented one of the first deep learning methods, called the wake-sleep algorithm, the affinity propagation algorithm for clustering and data summarization, and the factor graph notation for probability models. In the late 1990s, Frey was a leading researcher in the areas of computer vision, speech recognition, and digital communications. In 2002, a personal crisis led Frey to face the fact that there was a tragic gap between our ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Machine Learning
Machine learning (ML) is a field of inquiry devoted to understanding and building methods that 'learn', that is, methods that leverage data to improve performance on some set of tasks. It is seen as a part of artificial intelligence. Machine learning algorithms build a model based on sample data, known as training data, in order to make predictions or decisions without being explicitly programmed to do so. Machine learning algorithms are used in a wide variety of applications, such as in medicine, email filtering, speech recognition, agriculture, and computer vision, where it is difficult or unfeasible to develop conventional algorithms to perform the needed tasks.Hu, J.; Niu, H.; Carrasco, J.; Lennox, B.; Arvin, F.,Voronoi-Based Multi-Robot Autonomous Exploration in Unknown Environments via Deep Reinforcement Learning IEEE Transactions on Vehicular Technology, 2020. A subset of machine learning is closely related to computational statistics, which focuses on making predicti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mutations
In biology, a mutation is an alteration in the nucleic acid sequence of the genome of an organism, virus, or extrachromosomal DNA. Viral genomes contain either DNA or RNA. Mutations result from errors during DNA or viral replication, mitosis, or meiosis or other types of damage to DNA (such as pyrimidine dimers caused by exposure to ultraviolet radiation), which then may undergo error-prone repair (especially microhomology-mediated end joining), cause an error during other forms of repair, or cause an error during replication (translesion synthesis). Mutations may also result from insertion or deletion of segments of DNA due to mobile genetic elements. Mutations may or may not produce detectable changes in the observable characteristics (phenotype) of an organism. Mutations play a part in both normal and abnormal biological processes including: evolution, cancer, and the development of the immune system, including junctional diversity. Mutation is the ultimate source o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Manitoba
The University of Manitoba (U of M, UManitoba, or UM) is a Canadian public research university in the province of Manitoba.''University of Manitoba Act'', C.C.S.M. c. U60. Retrieved on July 15, 2008 Founded in 1877, it is the first of . Both by total student enrolment and campus area, the U of M is the largest university in the province of Manitoba and the 17th-largest in all of Canada. Its main campus is located in the |
University Of Calgary
The University of Calgary (U of C or UCalgary) is a public research university located in Calgary, Alberta, Canada. The University of Calgary started in 1944 as the Calgary branch of the University of Alberta, founded in 1908, prior to being instituted into a separate, autonomous university in 1966. It is composed of 14 faculties and over 85 research institutes and centres. The main campus is located in the northwest quadrant of the city near the Bow River and a smaller south campus is located in the city centre. The main campus houses most of the research facilities and works with provincial and federal research and regulatory agencies, several of which are housed next to the campus such as the Geological Survey of Canada. The main campus covers approximately . A member of the U15, the University of Calgary is also one of Canada's top research universities (based on the number of Canada Research Chairs). The university has a sponsored research revenue of $380.4 million, wi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Drug Candidate
In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate pharmaceutical drug, medications are discovered. Historically, drugs were discovered by identifying the active ingredient from traditional remedies or by serendipity, serendipitous discovery, History of penicillin, as with penicillin. More recently, chemical library, chemical libraries of synthetic small molecules, natural products or extracts were screened in intact cells or whole organisms to identify substances that had a desirable therapeutic effect in a process known as classical pharmacology. After Human Genome Project, sequencing of the human genome allowed rapid cloning and synthesis of large quantities of purified proteins, it has become common practice to use high throughput screening of large compounds libraries against isolated biological targets which are hypothesized to be disease-modifying in a process known as reverse pharmacology. Hits from these screens ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Washington Post
''The Washington Post'' (also known as the ''Post'' and, informally, ''WaPo'') is an American daily newspaper published in Washington, D.C. It is the most widely circulated newspaper within the Washington metropolitan area and has a large national audience. Daily broadsheet editions are printed for D.C., Maryland, and Virginia. The ''Post'' was founded in 1877. In its early years, it went through several owners and struggled both financially and editorially. Financier Eugene Meyer purchased it out of bankruptcy in 1933 and revived its health and reputation, work continued by his successors Katharine and Phil Graham (Meyer's daughter and son-in-law), who bought out several rival publications. The ''Post'' 1971 printing of the Pentagon Papers helped spur opposition to the Vietnam War. Subsequently, in the best-known episode in the newspaper's history, reporters Bob Woodward and Carl Bernstein led the American press's investigation into what became known as the Watergate scandal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Exponential Growth
Exponential growth is a process that increases quantity over time. It occurs when the instantaneous rate of change (that is, the derivative) of a quantity with respect to time is proportional to the quantity itself. Described as a function, a quantity undergoing exponential growth is an exponential function of time, that is, the variable representing time is the exponent (in contrast to other types of growth, such as quadratic growth). If the constant of proportionality is negative, then the quantity decreases over time, and is said to be undergoing exponential decay instead. In the case of a discrete domain of definition with equal intervals, it is also called geometric growth or geometric decay since the function values form a geometric progression. The formula for exponential growth of a variable at the growth rate , as time goes on in discrete intervals (that is, at integer times 0, 1, 2, 3, ...), is x_t = x_0(1+r)^t where is the value of at ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Digital Communications
Data transmission and data reception or, more broadly, data communication or digital communications is the transfer and reception of data in the form of a digital bitstream or a digitized analog signal transmitted over a point-to-point or point-to-multipoint communication channel. Examples of such channels are copper wires, optical fibers, wireless communication using radio spectrum, storage media and computer buses. The data are represented as an electromagnetic signal, such as an electrical voltage, radiowave, microwave, or infrared signal. Analog transmission is a method of conveying voice, data, image, signal or video information using a continuous signal which varies in amplitude, phase, or some other property in proportion to that of a variable. The messages are either represented by a sequence of pulses by means of a line code (''baseband transmission''), or by a limited set of continuously varying waveforms (''passband transmission''), using a digital modulation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Speech Recognition
Speech recognition is an interdisciplinary subfield of computer science and computational linguistics that develops methodologies and technologies that enable the recognition and translation of spoken language into text by computers with the main benefit of searchability. It is also known as automatic speech recognition (ASR), computer speech recognition or speech to text (STT). It incorporates knowledge and research in the computer science, linguistics and computer engineering fields. The reverse process is speech synthesis. Some speech recognition systems require "training" (also called "enrollment") where an individual speaker reads text or isolated vocabulary into the system. The system analyzes the person's specific voice and uses it to fine-tune the recognition of that person's speech, resulting in increased accuracy. Systems that do not use training are called "speaker-independent" systems. Systems that use training are called "speaker dependent". Speech recognition ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Computer Vision
Computer vision is an interdisciplinary scientific field that deals with how computers can gain high-level understanding from digital images or videos. From the perspective of engineering, it seeks to understand and automate tasks that the human visual system can do. Computer vision tasks include methods for acquiring, processing, analyzing and understanding digital images, and extraction of high-dimensional data from the real world in order to produce numerical or symbolic information, e.g. in the forms of decisions. Understanding in this context means the transformation of visual images (the input of the retina) into descriptions of the world that make sense to thought processes and can elicit appropriate action. This image understanding can be seen as the disentangling of symbolic information from image data using models constructed with the aid of geometry, physics, statistics, and learning theory. The scientific discipline of computer vision is concerned with the theory ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Factor Graph
A factor graph is a bipartite graph representing the factorization of a function. In probability theory and its applications, factor graphs are used to represent factorization of a probability distribution function, enabling efficient computations, such as the computation of marginal distributions through the sum-product algorithm. One of the important success stories of factor graphs and the sum-product algorithm is the decoding of capacity-approaching error-correcting codes, such as LDPC and turbo codes. Factor graphs generalize constraint graphs. A factor whose value is either 0 or 1 is called a constraint. A constraint graph is a factor graph where all factors are constraints. The max-product algorithm for factor graphs can be viewed as a generalization of the arc-consistency algorithm for constraint processing. Definition A factor graph is a bipartite graph representing the factorization of a function. Given a factorization of a function g(X_1,X_2,\dots,X_n), :g(X_1 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Affinity Propagation
In statistics and data mining, affinity propagation (AP) is a Cluster analysis, clustering algorithm based on the concept of "message passing" between data points. Unlike clustering algorithms such as K-means clustering, -means or K-medoids, -medoids, affinity propagation does not require the number of clusters to be determined or estimated before running the algorithm. Similar to -medoids, affinity propagation finds "exemplars," members of the input set that are representative of clusters. Algorithm Let through be a set of data points, with no assumptions made about their internal structure, and let be a function that quantifies the similarity between any two points, such that if and only if, iff is more similar to than to . For this example, the negative squared distance of two data points was used i.e. for points and , s(i,k) = - \left\, x_i - x_k \right\, ^2 The diagonal of (i.e. s(i,i)) is particularly important, as it represents the instance preference, meaning how l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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