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Brain Atlas
A brain atlas is composed of serial sections along different anatomical planes of the healthy or diseased developing or adult animal or human brain where each relevant brain structure is assigned a number of coordinates to define its outline or volume. Brain atlases are contiguous, comprehensive results of visual brain mapping and may include anatomical, genetic or functional features. A functional brain atlas is made up of N regions of interest, where these regions are typically defined as spatially contiguous and functionally coherent patches of gray matter. In most atlases, the three dimensions are: latero-lateral (x), dorso-ventral (y) and rostro- caudal (z). The possible sections are * coronal * sagittal * transverse Surface maps are sometimes used in addition to the 3D serial section maps Besides the human brain, brain atlases exist for the brains of the mouse, rhesus macaques, ''Drosophila'', pig and others. Notable examples include the Allen Brain Atlas, BrainMaps, Bi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anatomical Plane
An anatomical plane is a hypothetical plane used to transect the body, in order to describe the location of structures or the direction of movements. In human and animal anatomy, three principal planes are used: * The sagittal plane or lateral plane (''longitudinal, anteroposterior'') is a plane parallel to the sagittal suture. It divides the body into left and right. * The coronal plane or frontal plane (''vertical'') divides the body into dorsal and ventral (back and front, or posterior and anterior) portions. * The transverse plane or axial plane (''horizontal'') divides the body into cranial and caudal (head and tail) portions. Terminology There could be any number of sagittal planes; however, there is only one cardinal sagittal plane. The term ''cardinal'' refers to the one plane that divides the body into equal segments, with exactly one half of the body on either side of the cardinal plane. The term ''cardinal plane'' appears in some texts as the ''principal plane''. The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rhesus Macaque
The rhesus macaque (''Macaca mulatta''), colloquially rhesus monkey, is a species of Old World monkey. There are between six and nine recognised subspecies that are split between two groups, the Chinese-derived and the Indian-derived. Generally brown or grey in colour, it is in length with a tail and weighs . It is native to South, Central, and Southeast Asia and has the widest geographic range of all non-human primates, occupying a great diversity of altitudes and a great variety of habitats, from grasslands to arid and forested areas, but also close to human settlements. Feral colonies are found in the United States, thought to be either released by humans or escapees after hurricanes destroyed zoo and wildlife park facilities. The rhesus macaque is diurnal, arboreal, and terrestrial. It is mostly herbivorous, mainly eating fruit, but will also consume seeds, roots, buds, bark, and cereals. Studies show almost 100 different plant species in its diet. Rhesus macaques are gener ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stereotaxic Atlas
Stereotaxic atlas is a number of records of brain structure of a particular animal accompanied with coordinates used in stereotactic surgery. External linksA Stereotaxic Atlas Of The Brain Of The Zebra Finch Neurosurgery {{surgery-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neuroanatomy
Neuroanatomy is the study of the structure and organization of the nervous system. In contrast to animals with radial symmetry, whose nervous system consists of a distributed network of cells, animals with bilateral symmetry have segregated, defined nervous systems. Their neuroanatomy is therefore better understood. In vertebrates, the nervous system is segregated into the internal structure of the brain and spinal cord (together called the central nervous system, or CNS) and the routes of the nerves that connect to the rest of the body (known as the peripheral nervous system, or PNS). The delineation of distinct structures and regions of the nervous system has been critical in investigating how it works. For example, much of what neuroscientists have learned comes from observing how damage or "lesions" to specific brain areas affects behavior or other neural functions. For information about the composition of non-human animal nervous systems, see nervous system. For information ab ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Connectome
A connectome () is a comprehensive map of neural connections in the brain, and may be thought of as its "wiring diagram". An organism's nervous system is made up of neurons which communicate through synapses. A connectome is constructed by tracing the neuron in a nervous system and mapping where neurons are connected through synapses. The significance of the connectome stems from the realization that the structure and function of the human brain are intricately linked, through multiple levels and modes of brain connectivity. There are strong natural constraints on which neurons or neural populations can interact, or how strong or direct their interactions are. Indeed, the foundation of human cognition lies in the pattern of dynamic interactions shaped by the connectome. Despite such complex and variable structure-function mappings, the connectome is an indispensable basis for the mechanistic interpretation of dynamic brain data, from single-cell recordings to functional neur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
BigBrain
BigBrain is a freely accessible high-resolution 3D digital atlas of the human brain, released in June 2013 by a team of researchers at the Montreal Neurological Institute and the German Forschungszentrum Jülich and is part of the European Human Brain Project. The isotropic 3D spatial resolution of the BigBrain atlas is 20 μm, much finer than the typical 1 mm resolution of other existing 3D models of the human brain such as the Allen Brain Atlas. In 2014, BigBrain was cited in the top 10 MIT Technology Review. Acquisition The atlas was created from the brain of an unidentified 65-year-old man (it was "65-year-old female", according to "BigBrain: An Ultrahigh-Resolution3D Human Brain Model", page 1472, Amunts K et al, SCIENCE, 21 JUNE 2013 VOL 340) who died with no known brain pathology. His brain, after being removed from the skull, was first scanned using an MRI machine, then embedded in paraffin and sliced into 7,404 20 μm thick sections using a large-scale mic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
BrainMaps
BrainMaps is an NIH-funded interactive zoomable high-resolution digital brain atlas and virtual microscope that is based on more than 140 million megapixels (140 terabytes) of scanned images of serial sections of both primate and non-primate brains and that is integrated with a high-speed database for querying and retrieving data about brain structure and function over the internet. Currently featured are complete brain atlas datasets for 16 species; a few of which are: ''Macaca mulatta'', '' Chlorocebus aethiops'', ''Felis silvestris catus'', ''Mus musculus'', ''Rattus norvegicus'', and ''Tyto alba''. The project's principal investigator was UC Davis neuroscientist Ted Jones from 2005 through 2011, after which the role was taken by W. Martin Usrey. Description BrainMaps uses multiresolution image formats for representing massive brain images, and a dHTML/Javascript front-end user interface for image navigation, both similar to the way that Google Maps works for geospatial da ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Allen Brain Atlas
The Allen Mouse and Human Brain Atlases are projects within the Allen Institute for Brain Science which seek to combine genomics with neuroanatomy by creating gene expression maps for the mouse and human brain. They were initiated in September 2003 with a $100 million donation from Paul G. Allen and the first atlas went public in September 2006. , seven brain atlases have been published: Mouse Brain Atlas, Human Brain Atlas, Developing Mouse Brain Atlas, Developing Human Brain Atlas, Mouse Connectivity Atlas, Non-Human Primate Atlas, and Mouse Spinal Cord Atlas. There are also three related projects with data banks: Glioblastoma, Mouse Diversity, and Sleep. It is the hope of the Allen Institute that their findings will help advance various fields of science, especially those surrounding the understanding of neurobiological diseases. The atlases are free and available for public use online. History In 2001, Paul Allen gathered a group of scientists, including James Watson and St ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Drosophila
''Drosophila'' () is a genus of flies, belonging to the family Drosophilidae, whose members are often called "small fruit flies" or (less frequently) pomace flies, vinegar flies, or wine flies, a reference to the characteristic of many species to linger around overripe or rotting fruit. They should not be confused with the Tephritidae, a related family, which are also called fruit flies (sometimes referred to as "true fruit flies"); tephritids feed primarily on unripe or ripe fruit, with many species being regarded as destructive agricultural pests, especially the Mediterranean fruit fly. One species of ''Drosophila'' in particular, ''D. melanogaster'', has been heavily used in research in genetics and is a common model organism in developmental biology. The terms "fruit fly" and "''Drosophila''" are often used synonymously with ''D. melanogaster'' in modern biological literature. The entire genus, however, contains more than 1,500 species and is very diverse in appearance, be ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mouse Brain
The mouse brain refers to the brain of Mus musculus. Various brain atlases exist. For reasons of reproducibility, genetically characterized, stable strains like C57BL/6 were chosen to produce high-resolution images and databases. Well known online resources include: *Allen Brain Atlas * Mouse Brain LibraryHigh resolution mouse brain atlas*BrainMaps High-Resolution Brain Maps and Brain Atlases of ''Mus musculus'' Despite superficial differences, especially in size and weight, the mouse brain and its function can serve as a powerful animal model for study of human brain diseases or mental disorders (see e.g. Reeler, Chakragati mouse). This is because the genes responsible for building and operating both mouse and human brain are 90% identical. Transgenic mouse lines also allow neuroscientists to specifically target the labeling of certain cell types to probe the neural basis of fundamental processes. Anatomy The cerebral cortex of a mouse has around 8–14 million neurons while in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Brain
The human brain is the central organ of the human nervous system, and with the spinal cord makes up the central nervous system. The brain consists of the cerebrum, the brainstem and the cerebellum. It controls most of the activities of the body, processing, integrating, and coordinating the information it receives from the sense organs, and making decisions as to the instructions sent to the rest of the body. The brain is contained in, and protected by, the skull bones of the head. The cerebrum, the largest part of the human brain, consists of two cerebral hemispheres. Each hemisphere has an inner core composed of white matter, and an outer surface – the cerebral cortex – composed of grey matter. The cortex has an outer layer, the neocortex, and an inner allocortex. The neocortex is made up of six neuronal layers, while the allocortex has three or four. Each hemisphere is conventionally divided into four lobes – the frontal, temporal, parietal, and occipital lo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Transverse Plane
The transverse plane (also known as the horizontal plane, axial plane and transaxial plane) is an anatomical plane that divides the body into Anatomical terms of location#Superior and inferior, superior and inferior sections. It is perpendicular to the coronal plane, coronal and sagittal plane, sagittal planes. List of clinically relevant anatomical planes * Transverse ''thoracic plane'' * ''Xiphosternal plane'' (or xiphosternal junction) * ''Transpyloric plane'' * ''Subcostal plane'' * ''Umbilical plane'' (or transumbilical plane) * ''Supracristal plane'' * ''Intertubercular plane'' (or transtubercular plane) * ''Interspinous plane'' Clinically relevant anatomical planes with associated structures * The transverse ''thoracic plane'' ** Plane through T4 & T5 vertebral junction and Sternal angle, sternal angle of Louis. ** Marks the: *** Attachment of costal cartilage of rib 2 at the sternal angle; *** Aortic arch (beginning and end); *** Upper margin of Superior vena cava, SVC ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
