Biopreparat
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Biopreparat
The All-Union Science Production Association Biopreparat (russian: Биопрепарат, p=bʲɪəprʲɪpɐˈrat, lit: "biological preparation") was the Soviet agency created in April 1974, which spearheaded the largest and most sophisticated offensive biological warfare programme the world has ever seen. It was a vast, ostensibly civilian, network employing 30–40,000 personnel and incorporating five major military-focused research institutes, numerous design and instrument-making facilities, three pilot plants and five dual-use production plants. The network pursued major offensive R&D programmes which genetically engineered microbial strains to be resistant to an array of antibiotics. In addition, bacterial agents were created with the ability to produce various peptides, yielding strains with wholly new and unexpected pathogenic properties. History Establishment On the 24 April 1974, the USSR's Main Administration of the Microbiological Industry (''Glavmikrobioprom'') i ...
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Soviet Biological Weapons Program
The Soviet Union covertly operated the world's largest, longest, and most sophisticated biological weapons program, thereby violating its obligations as a party to the 1972 Biological Weapons Convention.Leitenberg, M., Zilinskas, R., & Kuhn, J. (2012). Conclusion. In ''The Soviet Biological Weapons Program'' (pp. 698-712). Cambridge, Massachusetts; London, England: Harvard University Press. Retrieved February 7, 2021, from http://www.jstor.org/stable/j.ctt2jbscf.30 The program began in the 1920s and lasted until at least September 1992 but has possibly been continued by Russia after that. During World War II, Joseph Stalin was forced to move his biological warfare (BW) operations out of the way of advancing German forces and may have used tularemia against German troops in 1942 near Stalingrad. By 1960, numerous BW research facilities existed throughout the Soviet Union. Although the USSR also signed the 1972 Biological Weapons Convention (BWC), the Soviets subsequently augmen ...
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Kanatjan Alibekov
Kanatzhan "Kanat" Alibekov ( kk, Қанатжан Байзақұлы Әлібеков, Qanatjan Baizaqūly Älıbekov; russian: Канатжан Алибеков, Kanatzhan Alibekov; born 1950), known as Kenneth "Ken" Alibek since 1992, is a Kazakhstani-American microbiologist, and biological warfare (BW) administrative management expert. He rose rapidly in the ranks of the Soviet Army to become the First Deputy Director of Biopreparat, with a rank of Colonel, during which time he claimed to oversee a vast program of 40 BW facilities with 32,000 employees. During his career as a Soviet bioweaponeer, in the late 1970s and 1980s, Alibekov managed projects that included weaponizing glanders and Marburg hemorrhagic fever, and created Russia's first tularemia bomb. Jacobsen, Annie (2015), ''The Pentagon's Brain: An Uncensored History of DARPA, America's Top Secret Military Research Agency''; New York: Little, Brown and Company, pg 293. His most prominent accomplishment was the cre ...
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Vladimir Pasechnik
Vladimir Artemovich Pasechnik (12 October 1937 Stalingrad, USSR – 21 November 2001, Wiltshire, England) was a senior Soviet biologist and bioweaponeer who defected to the United Kingdom in 1989, alerting Western intelligence to the vast scope of Moscow's clandestine biological warfare (BW) programme, known as Biopreparat. His revelations that the program was ten times larger than previously suspected were confirmed in 1992 with the defection to the United States of Colonel Kanatjan Alibekov, the No. 2 scientist for the program. Biography A native of Leningrad, many members of Pasechnik's family, including his parents, perished in the Nazi siege of that city during World War II. Pasechnik studied at the Leningrad Polytechnical Institute, where he was one of the institute's brightest stars, graduating at the top of his class. Pasechnik initially specialised in the study of polymers for biological uses at the Institute of High Molecular Compounds in Leningrad. The intent was ...
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Stepnogorsk Scientific And Technical Institute For Microbiology
The Stepnogorsk Scientific and Technical Institute for Microbiology, also known as the Scientific Experimental and Production Base, was one of the premier biological warfare facilities operated by the Soviet Union. It was the only Biopreparat facility to be built outside of Russia proper, and one of the few ever visited officially by Western experts. As of 1998 the site conducted civilian biological research overseen by director Vladimir Bugreyev. At the time the United States Department of State and the U.S. Civilian Research & Development Foundation provided significant funds supporting civilian research at Stepnogorsk. History The facility was built in 1982, ten kilometers from Stepnogorsk, Kazakhstan, in the wake of the accident at Sverdlovsk. It was built to develop and produce large quantities of weaponized anthrax, almost 300 tons annually, in order to fill the production gap caused by a potential shutdown of their Sverdlovsk facility.Miller, Judith; Engelberg, Stephen; an ...
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Vector State Research Center Of Virology And Biotechnology
The State Research Center of Virology and Biotechnology VECTOR, also known as the Vector Institute (russian: Государственный научный центр вирусологии и биотехнологии „Вектор“, Gosudarstvennyy nauchnyy tsentr virusologii i biotekhnologii "Vektor"), is a biological research center in Koltsovo, Novosibirsk Oblast, Russia. It has research facilities and capabilities for all levels of Biological Hazard, CDC Levels 1–4. It is one of two official repositories for the now-eradicated smallpox virus, and was part of the system of laboratories known as the Biopreparat. The facility was upgraded and secured using modern cameras, motion sensors, fences and biohazard containment systems. Its relative seclusion makes security an easier task. Since its inception there has been an army regiment guarding the facility. At least in Soviet times the facility was a nexus for biological warfare research (see Soviet biological weapons ...
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Smallpox
Smallpox was an infectious disease caused by variola virus (often called smallpox virus) which belongs to the genus Orthopoxvirus. The last naturally occurring case was diagnosed in October 1977, and the World Health Organization (WHO) certified the global eradication of the disease in 1980, making it the only human disease to be eradicated. The initial symptoms of the disease included fever and vomiting. This was followed by formation of ulcers in the mouth and a skin rash. Over a number of days, the skin rash turned into the characteristic fluid-filled blisters with a dent in the center. The bumps then scabbed over and fell off, leaving scars. The disease was spread between people or via contaminated objects. Prevention was achieved mainly through the smallpox vaccine. Once the disease had developed, certain antiviral medication may have helped. The risk of death was about 30%, with higher rates among babies. Often, those who survived had extensive scarring of their ...
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Biological Weapons Convention
The Biological Weapons Convention (BWC), or Biological and Toxin Weapons Convention (BTWC), is a disarmament treaty that effectively bans biological and toxin weapons by prohibiting their development, production, acquisition, transfer, stockpiling and use. The treaty's full name is the Convention on the Prohibition of the Development, Production and Stockpiling of Bacteriological (Biological) and Toxin Weapons and on their Destruction. Having entered into force on 26 March 1975, the BWC was the first multilateral disarmament treaty to ban the production of an entire category of weapons of mass destruction. The convention is of unlimited duration. As of February 2022, 184 states have become party to the treaty. Four additional states have signed but not ratified the treaty, and another nine states have neither signed nor acceded to the treaty.Report on universalization activities, 2019 Meeting of States Parties to the Biological Weapons ConventionBWC/MSP/2019/3 Geneva, 8 October ...
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Leningrad
Saint Petersburg ( rus, links=no, Санкт-Петербург, a=Ru-Sankt Peterburg Leningrad Petrograd Piter.ogg, r=Sankt-Peterburg, p=ˈsankt pʲɪtʲɪrˈburk), formerly known as Petrograd (1914–1924) and later Leningrad (1924–1991), is the second-largest city in Russia. It is situated on the Neva River, at the head of the Gulf of Finland on the Baltic Sea, with a population of roughly 5.4 million residents. Saint Petersburg is the fourth-most populous city in Europe after Istanbul, Moscow and London, the most populous city on the Baltic Sea, and the world's northernmost city of more than 1 million residents. As Russia's Imperial capital, and a historically strategic port, it is governed as a federal city. The city was founded by Tsar Peter the Great on 27 May 1703 on the site of a captured Swedish fortress, and was named after apostle Saint Peter. In Russia, Saint Petersburg is historically and culturally associated with ...
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Brucellosis
Brucellosis is a highly contagious zoonosis caused by ingestion of unpasteurized milk or undercooked meat from infected animals, or close contact with their secretions. It is also known as undulant fever, Malta fever, and Mediterranean fever. The bacteria causing this disease, '' Brucella'', are small, Gram-negative, nonmotile, nonspore-forming, rod-shaped (coccobacilli) bacteria. They function as facultative intracellular parasites, causing chronic disease, which usually persists for life. Four species infect humans: ''B. abortus'', ''B. canis'', ''B. melitensis'', and ''B. suis''. ''B. abortus'' is less virulent than ''B. melitensis'' and is primarily a disease of cattle. ''B. canis'' affects dogs. ''B. melitensis'' is the most virulent and invasive species; it usually infects goats and occasionally sheep. ''B. suis'' is of intermediate virulence and chiefly infects pigs. Symptoms include profuse sweating and joint and muscle pain. Brucellosis has been recognized in animals a ...
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Francisella Tularensis
''Francisella tularensis'' is a pathogenic species of Gram-negative coccobacillus, an aerobic bacterium. It is nonspore-forming, nonmotile, and the causative agent of tularemia, the pneumonic form of which is often lethal without treatment. It is a fastidious, facultative intracellular bacterium, which requires cysteine for growth. Due to its low infectious dose, ease of spread by aerosol, and high virulence, ''F. tularensis'' is classified as a Tier 1 Select Agent by the U.S. government, along with other potential agents of bioterrorism such as ''Yersinia pestis, Bacillus anthracis'', and Ebola virus. When found in nature, ''Francisella tularensis'' can survive for several weeks at low temperatures in animal carcasses, soil, and water. In the laboratory, ''F. tularensis'' appears as small rods (0.2 by 0.2 µm), and is grown best at 35–37 °C. History This species was discovered in ground squirrels in Tulare County, California in 1911. ''Bacterium tularense'' was ...
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Yersinia Pestis
''Yersinia pestis'' (''Y. pestis''; formerly '' Pasteurella pestis'') is a gram-negative, non-motile, coccobacillus bacterium without spores that is related to both ''Yersinia pseudotuberculosis'' and ''Yersinia enterocolitica''. It is a facultative anaerobic organism that can infect humans via the Oriental rat flea (''Xenopsylla cheopis''). It causes the disease plague, which caused the first plague pandemic and the Black Death, the deadliest pandemic in recorded history. Plague takes three main forms: pneumonic, septicemic, and bubonic. ''Yersinia pestis'' is a parasite of its host, the rat flea, which is also a parasite of rats, hence ''Y. pestis'' is a hyperparasite. ''Y. pestis'' was discovered in 1894 by Alexandre Yersin, a Swiss/French physician and bacteriologist from the Pasteur Institute, during an epidemic of the plague in Hong Kong. Yersin was a member of the Pasteur school of thought. Kitasato Shibasaburō, a Japanese bacteriologist who practised Koch's me ...
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Bacillus Anthracis
''Bacillus anthracis'' is a gram-positive and rod-shaped bacterium that causes anthrax, a deadly disease to livestock and, occasionally, to humans. It is the only permanent ( obligate) pathogen within the genus '' Bacillus''. Its infection is a type of zoonosis, as it is transmitted from animals to humans. It was discovered by a German physician Robert Koch in 1876, and became the first bacterium to be experimentally shown as a pathogen. The discovery was also the first scientific evidence for the germ theory of diseases. ''B. anthracis'' measures about 3 to 5 μm long and 1 to 1.2 μm wide. The reference genome consists of a 5,227,419 bp circular chromosome and two extrachromosomal DNA plasmids, pXO1 and pXO2, of 181,677 and 94,830 bp respectively, which are responsible for the pathogenicity. It forms a protective layer called endospore by which it can remain inactive for many years and suddenly becomes infective under suitable environmental conditions. Because of the resil ...
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