Biopreparat
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The All-Union Science Production Association Biopreparat (russian: Биопрепарат, p=bʲɪəprʲɪpɐˈrat, lit: "biological preparation") was the Soviet agency created in April 1974, which spearheaded the largest and most sophisticated offensive biological warfare programme the world has ever seen. It was a vast, ostensibly civilian, network employing 30–40,000 personnel and incorporating five major military-focused research institutes, numerous design and instrument-making facilities, three pilot plants and five dual-use production plants. The network pursued major offensive R&D programmes which genetically engineered microbial strains to be resistant to an array of antibiotics. In addition, bacterial agents were created with the ability to produce various peptides, yielding strains with wholly new and unexpected pathogenic properties.


History


Establishment

On the 24 April 1974, the USSR's Main Administration of the Microbiological Industry (''Glavmikrobioprom'') issued Order 131 DSP which created the All-Union Science Production Association ''Biopreparat''. On the 26 June 1974, a number of the Soviet Union's existing dual-use BW facilities were transferred to the new agency. These included the Berdsk Chemical Factory and the Omutninsk Chemical Factory. The ''Biopreparat'' project was reportedly initiated by academician Yuri Anatol'evich Ovchinnikov, who convinced General Secretary
Leonid Brezhnev Leonid Ilyich Brezhnev; uk, links= no, Леонід Ілліч Брежнєв, . (19 December 1906– 10 November 1982) was a Soviet politician who served as General Secretary of the Communist Party of the Soviet Union between 1964 and ...
that development of
biological weapon A biological agent (also called bio-agent, biological threat agent, biological warfare agent, biological weapon, or bioweapon) is a bacterium, virus, protozoan, parasite, fungus, or toxin that can be used purposefully as a weapon in bioterroris ...
s was necessary.Alibek, K. and S. Handelman. ''Biohazard: The Chilling True Story of the Largest Covert Biological Weapons Program in the World - Told from Inside by the Man Who Ran it.'' 1999. Delta (2000)

/ref> The research at ''Biopreparat'' constituted a violation of the terms of the
Biological Weapons Convention The Biological Weapons Convention (BWC), or Biological and Toxin Weapons Convention (BTWC), is a disarmament treaty that effectively bans biological and toxin weapons by prohibiting their development, production, acquisition, transfer, stockpil ...
of 1972, which outlawed biological weapons.


Exposure in the West

''Biopreparat'''s R&D and production programmes were from the very outset subject to extraordinary levels of secrecy and compartmentalization. The first significant intelligence reaching the West regarding the nature and extent of this Soviet covert BW effort resulted from the defection to the UK in October 1989 of a high-level ''Biopreparat'' scientist, Vladimir Artemovich Pasechnik (1937–2001). The latter was able to provide a detailed account of the vast scope of Moscow's clandestine program. As a result of Pasechnik's testimony,
British Prime Minister The prime minister of the United Kingdom is the head of government of the United Kingdom. The prime minister advises the sovereign on the exercise of much of the royal prerogative, chairs the Cabinet and selects its ministers. As moder ...
Margaret Thatcher Margaret Hilda Thatcher, Baroness Thatcher (; 13 October 19258 April 2013) was Prime Minister of the United Kingdom from 1979 to 1990 and Leader of the Conservative Party from 1975 to 1990. She was the first female British prime ...
and
US President The president of the United States (POTUS) is the head of state and head of government of the United States of America. The president directs the executive branch of the federal government and is the commander-in-chief of the United States ...
George H. W. Bush were able to apply pressure on Soviet President Mikhail Gorbachev to open up Russia's germ warfare facilities to a team of outside inspectors. When the inspectors toured four of the sites in 1991, they were met with denials and evasions. Production tanks, the purpose of which seemed to be to manufacture large quantities of hazardous materials, were clean and sterile when presented to inspectors. Laboratories had been stripped of equipment before being presented to inspectors. Pasechnik's revelations that the program was much greater in scope than previously suspected were confirmed in 1992 with the travel to the United States of Colonel Kanatzhan Baizakovich Alibekov (b. 1950). The latter, who subsequently adopted the name of Ken Alibek, had served as First Deputy Director of ''Biopreparat'' from 1988 to 1992. Alibekov later wrote the book ''
Biohazard A biological hazard, or biohazard, is a biological substance that poses a threat to the health of living organisms, primarily humans. This could include a sample of a microorganism, virus or toxin that can adversely affect human health. A bioh ...
'' (1999) detailing publicly his extensive inside knowledge of the structure, goals, operations and achievements of ''Biopreparat''. He was also featured in the October 13, 1998 episode of ''
Frontline Front line refers to the forward-most forces on a battlefield. Front line, front lines or variants may also refer to: Books and publications * ''Front Lines'' (novel), young adult historical novel by American author Michael Grant * ''Frontlines ...
'' entitled "Plague War".


Changing role of ''Biopreparat'', 1985 - present

''Biopreparat'' had three distinct,and, at times overlapping, phases of its existence. From its origins in April 1974 through to the collapse of the Soviet Union in December 1991, and indeed for some undetermined time thereafter, it was engaged in a major offensive BW research programme. It also maintained five dual-use manufacturing plants. In March 1985, with the election by the Politboro of Mikhail Gorbachev as General Secretary of the CPSU, ''Biopreparat'' increased in size and political importance and began to emerge also as a major player with regard to the civil biopharmaceutical sector. By 1988, in this second phase, the ''Biopreparat'' network incorporated no less than 40 facilities, operating in 15 different cities and had control of domestic production of vaccines, antibiotics and other essential medicines. It was precisely at this moment that Alibekov emerged as a key interlocutor between ''Biopreparat'' and a number of Western pharmaceutical companies. In the third and final phase during the 2000s, ''Biopreparat'' was divested of control of nearly all R&D institutes and manufacturing facilities. Henceforward, it assumed a highly diminished role, focused on export control and other matters and only maintained a small headquarters staff.


Operations

''Biopreparat'' was a system of nominally civilian, research and design institutes, pilot plants and dual-use manufacturing facilities located mainly at sites in European Russia, in which a small army of scientists and technicians worked on bacterial and viral pathogens with a view to developing a new generation of biological weapons. It incorporated capacity with the potential to produce weaponized anthrax in the Soviet Union and was a leader in the development of new bioweapons technologies.


Facilities

The project incorporated the following R&D, design, pilot plant and production facilities: * All-Union Scientific-Research Design Institute of Applied Biochemistry (''VNIIbiokhimmashproekt''), Moscow *All-Union Scientific-Research Institute of Applied Microbiology (''VNII PM''), Obolensk * All-Union Institute of Highly Pure Biochemical Preparations (''VNII OChB''),
Leningrad Saint Petersburg ( rus, links=no, Санкт-Петербург, a=Ru-Sankt Peterburg Leningrad Petrograd Piter.ogg, r=Sankt-Peterburg, p=ˈsankt pʲɪtʲɪrˈburk), formerly known as Petrograd (1914–1924) and later Leningrad (1924–1991), i ...
*
All-Union Scientific-Research Institute of Molecular Biology The Soviet Union,. officially the Union of Soviet Socialist Republics. (USSR),. was a transcontinental country that spanned much of Eurasia from 1922 to 1991. A flagship communist state, it was nominally a federal union of fifteen nationa ...
(''VNII MB''), Kol'tsovo * Institute of Immunology, Lyubuchany *Experimental Design Bureau of Precision Biological Engineering (''OKB TBM''), Kirishi *Experimental Design Bureau of Automation Equipment (''OKBA''), Yoshkar-Ola * Stepnogorsk Scientific Experimental-Industrial Base (''SNOPB''),
Stepnogorsk Stepnogorsk ( kk, Степногорск, translit=Stepnogorsk; russian: Степногорск) is a town in Akmola Region, Kazakhstan. History Stepnogorsk was established in 1959, and has been a town since 1964. It is located about 200 km ...
, northern
Kazakhstan Kazakhstan, officially the Republic of Kazakhstan, is a transcontinental country located mainly in Central Asia and partly in Eastern Europe. It borders Russia to the north and west, China to the east, Kyrgyzstan to the southeast, Uzbeki ...
*Berdsk Scientific Experimental-Industrial Base (''BNOPB''), Berdsk *Omutninsk Scientific Experimental Industrial Base (''ONOPB''), Omutninsk *Berdsk Chemical Factory, Berdsk *Omutninsk Chemical Factory, Omutninsk


Pathogens

Research was conducted on a range of bacterial and viral pathogens with a view to their potential weaponization. These included: * '' Bacillus anthracis'' (the causative agent of anthrax) *''
Yersinia pestis ''Yersinia pestis'' (''Y. pestis''; formerly '' Pasteurella pestis'') is a gram-negative, non-motile, coccobacillus bacterium without spores that is related to both ''Yersinia pseudotuberculosis'' and ''Yersinia enterocolitica''. It is a facult ...
'' (the causative agent of plague) *''
Francisella tularensis ''Francisella tularensis'' is a pathogenic species of Gram-negative coccobacillus, an aerobic bacterium. It is nonspore-forming, nonmotile, and the causative agent of tularemia, the pneumonic form of which is often lethal without treatment. It is ...
'' (the causative agent of tularaemia) *
Brucella ''Brucella'' is a genus of Gram-negative bacteria, named after David Bruce (1855–1931). They are small (0.5 to 0.7 by 0.6 to 1.5 µm), non encapsulated, non motile, facultatively intracellular coccobacilli. ''Brucella'' spp. are the caus ...
sp. (the causative agent of Brucellosis) *
Smallpox virus Smallpox was an infectious disease caused by variola virus (often called smallpox virus) which belongs to the genus Orthopoxvirus. The last naturally occurring case was diagnosed in October 1977, and the World Health Organization (WHO) cer ...
*
Venezuelan equine encephalitis virus Venezuelan equine encephalitis virus is a mosquito-borne viral pathogen that causes Venezuelan equine encephalitis or encephalomyelitis (VEE). VEE can affect all equine species, such as horses, donkeys, and zebras. After infection, equines m ...
* Marburg virus *
Machupo virus Bolivian hemorrhagic fever (BHF), also known as black typhus or Ordog Fever, is a hemorrhagic fever and zoonotic infectious disease originating in Bolivia after infection by ''Machupo mammarenavirus''.Public Health Agency of Canada: ''Machupo V ...
The only reliable data with regard to production capacity of weaponised agents concerns ''SNOPB'' (Stepnogorsk). Here, the plant is estimated to have incorporated capacity for the production of around 300 metric tonnes of weaponized ''B. anthracis'' spores per ten-month production cycle.


Leaders


Directors

Major General (Reserves) Vsevolod Ivanovich Ogarkov (April 1974–1979) Colonel (Reserves) Anatolii Anatol'evich Miklashevskii (1979) Lieutenant General (Reserves) Yurii Tikhonovich Kalinin (1980 – April 2001)


First Deputy Directors

Major General (Reserves) Anatolii Andreevich Vorob'ev (1978–1988) Colonel (Reserves) Kanatzhan Baizakovich Alibekov (1988–1992)


See also

*
Soviet biological weapons program The Soviet Union covertly operated the world's largest, longest, and most sophisticated biological weapons program, thereby violating its obligations as a party to the 1972 Biological Weapons Convention.Leitenberg, M., Zilinskas, R., & Kuhn, J. ...
*
Ken Alibek Kanatzhan "Kanat" Alibekov ( kk, Қанатжан Байзақұлы Әлібеков, Qanatjan Baizaqūly Älıbekov; russian: Канатжан Алибеков, Kanatzhan Alibekov; born 1950), known as Kenneth "Ken" Alibek since 1992, is a Kazak ...
(defected in 1992) * Yuri Ovchinnikov *
Poison laboratory of the Soviet secret services The poison laboratory of the Soviet secret services, alternatively known as Laboratory 1, Laboratory 12, and Kamera (which means "The Cell" in Russian), was a covert research-and-development facility of the Soviet secret police agencies. Th ...
* Sergei Popov (defected in 1992) *
Porton Down Porton Down is a science park in Wiltshire, England, just northeast of the village of Porton, near Salisbury. It is home to two British government facilities: a site of the Ministry of Defence's Defence Science and Technology Laboratory (Dstl ...
- Comparable facility in England *
Dugway Proving Ground Dugway Proving Ground (DPG) is a U.S. Army facility established in 1942 to test biological and chemical weapons, located about southwest of Salt Lake City, Utah, United States, and south of the Utah Test and Training Range. Location Dugway P ...
and
Fort Detrick Fort Detrick () is a United States Army Futures Command installation located in Frederick, Maryland. Historically, Fort Detrick was the center of the U.S. biological weapons program from 1943 to 1969. Since the discontinuation of that program, it ...
- Comparable facilities in the United States.


References


External links


pbs.org

the-scientist.com




* * ttp://allnewspipeline.com/Ebola_Pox_Ultimate_Doomsday_Virus.php Is Ebola Pox The Ultimate Doomsday Virus Being Readied For Release? {{U.S.S.R. biological weapons Biological warfare Medical research institutes in the Soviet Union Soviet biological weapons program Defence companies of the Soviet Union 1973 establishments in the Soviet Union Pharmaceutical companies of the Soviet Union