BGR-34
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BGR-34
BGR-34 (Blood Glucose Regulator-34) is an Ayurvedic-derived product that is sold in India as an over-the-counter pill for the management of type 2 diabetes. It was developed in 2015 by two government-owned laboratories and launched commercially in 2016. It has been tested in only one, modest-sized, human trial. The drug has been heavily criticized, and without more clinical trials, its efficacy remains unproven. The manufacturers have refused to acknowledge the claims of inefficacy and other concerns. Development BGR-34 was co-developed by two national government-owned laboratories, National Botanical Research Institute (NBRI) and Central Institute for Medicinal and Aromatic Plants (CIMAP) under the patronage of the Council of Scientific and Industrial Research (CSIR). The formulation was publicized in September 2015 as NBRMAP-DB and it was launched commercially by AIMIL Pharmaceuticals (AIMIL) in June 2016. Upon launch, it was priced at ( USD) per 500 milligram tablet, whic ...
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AYUSH
The Ministry of Ayush, a ministry of the Government of India, is responsible for developing education, research and propagation of traditional medicine systems in India. Ayush is a name devised from the names of the alternative healthcare systems covered by the ministry: Ayurveda, Yoga & Naturopathy, Unani, Siddha, and Homeopathy. The Department of Indian Systems of Medicine and Homeopathy (ISM&H) was first established in 1995 under the Ministry of Health and Family Welfare. ISM&H was renamed as the Department of Ayurveda, Yoga and naturopathy, Unani, Siddha and Homeopathy or Department of AYUSH. The department was made into an official ministry by the Narendra Modi, Government of India in 2014. The ministry of Ayush has faced significant criticism for funding systems that lack biological plausibility and are either untested or conclusively proven as ineffective. Quality of research has been poor, and drugs have been launched without rigorous pharmacological studies and meaning ...
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Ministry Of AYUSH
The Ministry of Ayush, a ministry of the Government of India, is responsible for developing education, research and propagation of traditional medicine systems in India. Ayush is a name devised from the names of the alternative healthcare systems covered by the ministry: Ayurveda, Yoga & Naturopathy, Unani, Siddha, and Homeopathy. The Department of Indian Systems of Medicine and Homeopathy (ISM&H) was first established in 1995 under the Ministry of Health and Family Welfare. ISM&H was renamed as the Department of Ayurveda, Yoga and naturopathy, Unani, Siddha and Homeopathy or Department of AYUSH. The department was made into an official ministry by the Narendra Modi, Government of India in 2014. The ministry of Ayush has faced significant criticism for funding systems that lack biological plausibility and are either untested or conclusively proven as ineffective. Quality of research has been poor, and drugs have been launched without rigorous pharmacological studies and meaning ...
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Ayurveda
Ayurveda () is an alternative medicine system with historical roots in the Indian subcontinent. The theory and practice of Ayurveda is pseudoscientific. Ayurveda is heavily practiced in India and Nepal, where around 80% of the population report using it. Ayurveda therapies have varied and evolved over more than two millennia. Therapies include herbal medicines, special diets, meditation, yoga, massage, laxatives, enemas, and medical oils. Ayurvedic preparations are typically based on complex herbal compounds, minerals, and metal substances (perhaps under the influence of early Indian alchemy or ''rasashastra''). Ancient Ayurveda texts also taught surgical techniques, including rhinoplasty, kidney stone extractions, sutures, and the extraction of foreign objects. The main classical Ayurveda texts begin with accounts of the transmission of medical knowledge from the gods to sages, and then to human physicians. Printed editions of the '' Sushruta Samhita'' (''Sushruta's Compen ...
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Predatory Publisher
Predatory publishing, also write-only publishing or deceptive publishing, is an exploitative academic publishing business model that involves charging publication fees to authors without checking articles for quality and legitimacy, and without providing editorial and publishing services that legitimate academic journals provide, whether open access or not. The phenomenon of "open access predatory publishers" was first noticed by Jeffrey Beall, when he described "publishers that are ready to publish any article for payment". However, criticisms about the label "predatory" have been raised. A lengthy review of the controversy started by Beall appears in ''The Journal of Academic Librarianship''. Predatory publishers are so regarded because scholars are tricked into publishing with them, although some authors may be aware that the journal is poor quality or even fraudulent but publish in them anyway. New scholars from developing countries are said to be especially at risk of bein ...
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Drugs & Magic Remedies Act
The Drugs and Magic Remedies (Objectionable Advertisements) Act, 1954 is an Act of the Parliament of India which controls advertising of drugs in India. It prohibits advertisements of drugs and remedies that claim to have magical properties, and makes doing so a cognizable offence. Overview The act defines "magic remedy" as any talisman, mantra, amulet or any other object which is claimed to have miraculous powers to cure, diagnose, prevent or mitigate a disease in humans or animal. It also includes such devices that are claimed to have power to influence structure or function of an organ in humans or animals. The law prohibits advertising of drugs and remedies for *inducing miscarriage or preventing conception in women *improving or maintaining the capacity for sexual pleasure *correction of menstrual disorders *curing, diagnosing or preventing any disease or condition mentioned in an included schedule The original included schedule contained a list of 54 diseases and condit ...
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Advertising Standards Council Of India
The Advertising Standards Council of India (ASCI) is a voluntary self-regulatory organization of the advertising industry in India. Established in 1985, ASCI is registered as a non-profit company under section 25 of the Company Act. ASCI is committed to the cause of self-regulation in advertising, ensuring the protection of the interest of consumers. ASCI seeks to ensure that advertisements conform to its Code for Self-Regulation, which requires advertisements to be legal, decent, honest and truthful, and not hazardous or harmful while observing fairness in competition. ASCI looks into complaints across ALL MEDIA such as Print, TV, Radio, hoardings, SMS, Emailers, Internet/web-site, product packaging, brochures, promotional material and point of sale material etc. ASCI’s role has been acclaimed by various Government bodies including the Department of Consumer Affairs (DoCA), Food Safety and Standards Authority of India (FSSAI), Ministry of AYUSH as well as the Ministry of Info ...
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Intellectual Property In India
Intellectual property in India refers to the patents, copyrights and other intangible assets in India. Government Policy Indian government approved its first Intellectual Property Rights Policy in May 2016. Laws Copyrights The "Copyright Act, 1957" (as amended by the Copyright Amendment Act 2012) governs the subject of copyright law in India. The history of copyright law in India can be traced back to its colonial era under the British Empire. The Copyright Act, 1957 was the first post-independence copyright legislation in India and the law has been amended six times since 1957. The most recent amendment was in the year 2012, through the Copyright (Amendment) Act 2012. Trademarks "Indian trademark law" statutorily protects trademarks A trademark (also written trade mark or trade-mark) is a type of intellectual property consisting of a recognizable sign, design, or expression that identifies products or services from a particular source and distinguishes them fr ...
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Toxicology Testing
Toxicology testing, also known as safety assessment, or toxicity testing, is the process of determining the degree to which a substance of interest negatively impacts the normal biological functions of an organism, given a certain exposure duration, route of exposure, and substance concentration. Toxicology testing is often conducted by researchers who follow established toxicology test protocol for a certain substance, mode of exposure, exposure environment, duration of exposure, or for a particular organism of interest, or for a particular developmental stage of interest. Toxicology testing is commonly conducted during preclinical development for a substance intended for human exposure. Stages of ''in silico'', ''in vitro'' and ''in vivo'' research are conducted to determine safe exposure doses in model organisms. If necessary, the next phase of research involves human toxicology testing during a first-in-man study. Toxicology testing may be conducted by the pharmaceutical indu ...
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Contraindication
In medicine, a contraindication is a condition that serves as a reason not to take a certain medical treatment due to the harm that it would cause the patient. Contraindication is the opposite of indication, which is a reason to use a certain treatment. ''Absolute contraindications'' are contraindications for which there are no reasonable circumstances for undertaking a course of action. For example, children and teenagers with viral infections should not be given aspirin because of the risk of Reye syndrome, and a person with an anaphylactic food allergy should never eat the food to which they are allergic. Similarly, a person with hemochromatosis should not be administered iron preparations. ''Relative contraindications'' are contraindications for circumstances in which the patient is at higher risk of complications from treatment, but these risks may be outweighed by other considerations or mitigated by other measures. For example, a pregnant woman should normally avoid gett ...
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Narendra Modi
Narendra Damodardas Modi (; born 17 September 1950) is an Indian politician serving as the 14th and current Prime Minister of India since 2014. Modi was the Chief Minister of Gujarat from 2001 to 2014 and is the Member of Parliament from Varanasi. He is a member of the Bharatiya Janata Party (BJP) and of the Rashtriya Swayamsevak Sangh (RSS), a right-wing Hindu nationalist paramilitary volunteer organisation. He is the longest serving prime minister from outside the Indian National Congress. Modi was born and raised in Vadnagar in northeastern Gujarat, where he completed his secondary education. He was introduced to the RSS at age eight. He has reminisced about helping out after school at his father's tea stall at the Vadnagar railway station. At age 18, Modi was married to Jashodaben Chimanlal Modi, whom he abandoned soon after. He first publicly acknowledged her as his wife more than four decades later when required to do so by Indian law, but has made no contact with ...
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Glycated Hemoglobin
Glycated hemoglobin, also known as HbA1c, glycohemoglobin, hemoglobin A1c, A1C, is a form of hemoglobin (Hb) that is chemically linked to a sugar. Most monosaccharides, including glucose, galactose and fructose, spontaneously (i.e. non-enzymatically) bond with hemoglobin when present in the bloodstream. However, glucose is less likely to do so than galactose and fructose (13% that of fructose and 21% that of galactose), which may explain why glucose is used as the primary metabolic fuel in humans. The formation of the sugar-hemoglobin linkage indicates the presence of excessive sugar in the bloodstream, often indicative of diabetes in high concentration (HbA1c ≥ 5.7%). A1C is of particular interest because it is easy to detect. The process by which sugars attach to hemoglobin is called glycation. HbA1c is a measure of the component of hemoglobin. HbA1c is measured primarily to determine the three-month average blood sugar level and can be used as a diagnostic test for diabet ...
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Postprandial Glucose Test
A postprandial glucose (PPG) test is a blood glucose test that determines the amount of glucose, in the plasma after a meal. The diagnosis is typically restricted to ''postprandial hyperglycemia'' due to lack of strong evidence of co-relation with a diagnosis of diabetes''.'' American Diabetes Association do not recommend a PPG test for determining diabetes; it though notes that postprandial hyperglycemia does contribute to elevated glycated hemoglobin levels (a primary factor behind diabetes) and recommends testing and management of PPG levels for those patients who maintain optimum pre-prandial blood glucose levels but have high A1C values. Carbohydrate in the form of glucose is one of the main constituents of foods and assimilation starts within about 10 minutes. The subsequent rate of absorption of carbohydrates in conjunction with the resultant rates of secretion of insulin and glucagon secretion affects the time-weighed PPG profile. In non-diabetic individuals, levels peak ...
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