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Postprandial Glucose Test
A postprandial glucose (PPG) test is a blood glucose test that determines the amount of glucose, in the plasma after a meal. The diagnosis is typically restricted to ''postprandial hyperglycemia'' due to lack of strong evidence of co-relation with a diagnosis of diabetes''.'' American Diabetes Association do not recommend a PPG test for determining diabetes; it though notes that postprandial hyperglycemia does contribute to elevated glycated hemoglobin levels (a primary factor behind diabetes) and recommends testing and management of PPG levels for those patients who maintain optimum pre-prandial blood glucose levels but have high A1C values. Carbohydrate in the form of glucose is one of the main constituents of foods and assimilation starts within about 10 minutes. The subsequent rate of absorption of carbohydrates in conjunction with the resultant rates of secretion of insulin and glucagon secretion affects the time-weighed PPG profile. In non-diabetic individuals, levels peak ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blood Glucose Test
Many types of glucose tests exist and they can be used to estimate blood sugar levels at a given time or, over a longer period of time, to obtain average levels or to see how fast body is able to normalize changed glucose levels. Eating food for example leads to elevated blood sugar levels. In healthy people these levels quickly return to normal via increased cellular glucose uptake which is primarily mediated by increase in blood insulin levels. Glucose tests can reveal temporary/long-term hyperglycemia or hypoglycemia. These conditions may not have obvious symptoms and can damage organs in the long-term. Abnormally high/low levels, slow return to normal levels from either of these conditions and/or inability to normalize blood sugar levels means that the person being tested probably has some kind of medical condition like type 2 diabetes which is caused by cellular insensitivity to insulin. Glucose tests are thus often used to diagnose such conditions . Testing methods Tests th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glucose
Glucose is a simple sugar with the molecular formula . Glucose is overall the most abundant monosaccharide, a subcategory of carbohydrates. Glucose is mainly made by plants and most algae during photosynthesis from water and carbon dioxide, using energy from sunlight, where it is used to make cellulose in cell walls, the most abundant carbohydrate in the world. In energy metabolism, glucose is the most important source of energy in all organisms. Glucose for metabolism is stored as a polymer, in plants mainly as starch and amylopectin, and in animals as glycogen. Glucose circulates in the blood of animals as blood sugar. The naturally occurring form of glucose is -glucose, while -glucose is produced synthetically in comparatively small amounts and is less biologically active. Glucose is a monosaccharide containing six carbon atoms and an aldehyde group, and is therefore an aldohexose. The glucose molecule can exist in an open-chain (acyclic) as well as ring (cyclic) form. Gluco ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blood Plasma
Blood plasma is a light amber-colored liquid component of blood in which blood cells are absent, but contains proteins and other constituents of whole blood in suspension. It makes up about 55% of the body's total blood volume. It is the intravascular part of extracellular fluid (all body fluid outside cells). It is mostly water (up to 95% by volume), and contains important dissolved proteins (6–8%; e.g., serum albumins, globulins, and fibrinogen), glucose, clotting factors, electrolytes (, , , , , etc.), hormones, carbon dioxide (plasma being the main medium for excretory product transportation), and oxygen. It plays a vital role in an intravascular osmotic effect that keeps electrolyte concentration balanced and protects the body from infection and other blood-related disorders. Blood plasma is separated from the blood by spinning a vessel of fresh blood containing an anticoagulant in a centrifuge until the blood cells fall to the bottom of the tube. The blood plasma is t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Diabetes Association
The American Diabetes Association (ADA) is a United States-based nonprofit that seeks to educate the public about diabetes and to help those affected by it through funding research to manage, cure and prevent diabetes (including type 1 diabetes, type 2 diabetes, gestational diabetes, and pre-diabetes). It is a network of 565,000 volunteers which includes 20,000 healthcare professionals and administration staff members. Historical background The ADA was formerly founded in 1939. It was founded by six physicians − including Dr. Herman O. Mosenthal, Dr. Joseph T. Beardwood Jr., Dr. Joseph H. Barach, and Dr. E. S. Dillion − at their annual meeting of the American College of Physicians. Each year the ADA hosts Scientific Sessions, a meeting for diabetes professionals. The ADA has nearly 20,000 members. In the early 2000s, the ADA struck a three-year, $1.5 million sponsorship deal with Cadbury-Schweppes, the world's largest confectioner products including Diet-Rite sodas, Sna ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glycated Hemoglobin
Glycated hemoglobin, also known as HbA1c, glycohemoglobin, hemoglobin A1c, A1C, is a form of hemoglobin (Hb) that is chemically linked to a sugar. Most monosaccharides, including glucose, galactose and fructose, spontaneously (i.e. non-enzymatically) bond with hemoglobin when present in the bloodstream. However, glucose is less likely to do so than galactose and fructose (13% that of fructose and 21% that of galactose), which may explain why glucose is used as the primary metabolic fuel in humans. The formation of the sugar-hemoglobin linkage indicates the presence of excessive sugar in the bloodstream, often indicative of diabetes in high concentration (HbA1c ≥ 5.7%). A1C is of particular interest because it is easy to detect. The process by which sugars attach to hemoglobin is called glycation. HbA1c is a measure of the component of hemoglobin. HbA1c is measured primarily to determine the three-month average blood sugar level and can be used as a diagnostic test for diabet ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Assimilation (biology)
Assimilation is the process of absorption of vitamins, minerals, and other chemicals from food as part of the nutrition of an organism. In humans, this is always done with a chemical breakdown (enzymes and acids) and physical breakdown (oral mastication and stomach churning). The second process of bio assimilation is the chemical alteration of substances in the bloodstream by the liver or cellular secretions. Although a few similar compounds can be absorbed in digestion bio assimilation, the bioavailability of many compounds is dictated by this second process since both the liver and cellular secretions can be very specific in their metabolic action (see chirality). This second process is where the absorbed food reaches the cells via the liver. Most foods are composed of largely indigestible components depending on the enzymes and effectiveness of an animal's digestive tract. The most well-known of these indigestible compounds is cellulose; the basic chemical polymer in the m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
International Diabetes Federation
The International Diabetes Federation (IDF) is an umbrella organization of over 230 national diabetes associations in more than 160 countries and territories. The Federation has been leading the global diabetes community since 1950. It is headquartered in Brussels, Belgium. It represents the interests of the growing number of people with diabetes and those at risk. IDF's mission is to promote diabetes care, prevention and a cure worldwide. According to the latest IDF figures, there are currently 463 million people living with diabetes and the total is expected to rise to 700 million by 2045. Over 75% of people with diabetes live in low- and middle-income countries and half of adults living with diabetes are undiagnosed. Organization IDF is divided into seven regions, with the aim of strengthening the work of national diabetes associations and enhancing the collaboration between them. IDF's national diabetes associations are divided into the following regions: Africa (AFR), Europe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Macrovascular Disease
Macrovascular disease is a disease of any large (''macro'') blood vessels in the body. It is a disease of the large blood vessels, including the coronary arteries, the aorta, and the sizable arteries in the brain and in the limbs. This sometimes occurs when a person has had diabetes for an extended period of time. Fat and blood clots build up in the large blood vessels and stick to the vessel walls. Three common macrovascular diseases are coronary disease (in the heart), cerebrovascular disease (in the brain), and peripheral vascular disease (in the limbs) Macrovascular disease (macroangiopathy) refers to atherosclerosis. Atherosclerosis is a form of arteriosclerosis (thickening and hardening of arterial walls), characterized by plaque deposits of lipids, fibrous connective tissue, calcium, and other blood substances. Atherosclerosis, by definition, affects only medium and large arteries (excluding arterioles). Macrovascular disease is associated with the development of coronar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Obesity Reviews
''Obesity Reviews'' is a monthly peer-reviewed medical journal, established in 2000, which publishes reviews on all obesity-related disciplines. It is the official journal of the World Obesity Federation and published on their behalf by Wiley-Blackwell. The editor-in-chief is David A. York (Utah State University). Abstracting and indexing The journal is abstracted and indexed in: According to the ''Journal Citation Reports'', the journal has a 2017 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as ... of 8.483. References External links * {{Official website, https://onlinelibrary.wiley.com/journal/1467789x World Obesity Federation Nutrition and dietetics journals Wiley-Blackwell academic journals Monthly journals Publications established in 2000 English-lan ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
OGTT
The glucose tolerance test (GTT, not to be confused with GGT test) is a medical test in which glucose is given and blood samples taken afterward to determine how quickly it is cleared from the blood. The test is usually used to test for diabetes, insulin resistance, impaired beta cell function, and sometimes reactive hypoglycemia and acromegaly, or rarer disorders of carbohydrate metabolism. In the most commonly performed version of the test, an ''oral glucose tolerance test'' (OGTT), a standard dose of glucose is ingested by mouth and blood levels are checked two hours later. Many variations of the GTT have been devised over the years for various purposes, with different standard doses of glucose, different routes of administration, different intervals and durations of sampling, and various substances measured in addition to blood glucose. History The glucose tolerance test was first described in 1923 by Jerome W. Conn. The test was based on the previous work in 1913 by A. T. B ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Postprandial Dip
In medicine and specifically endocrinology, postprandial dip is a term used to refer to mild hypoglycemia occurring after ingestion of a heavy meal. The dip is thought to be caused by a drop in blood glucose resulting from the body's own normal insulin secretion, which in turn is a response to the glucose load represented by the meal. While postprandial dip is usually physiological after a generous meal, a very sharp or sustained drop in blood glucose may be associated with a disorder of glucose metabolism. See also * Postprandial somnolence * Glucose metabolism * Lateral hypothalamus * Insulin resistance * Hypoglycemia * Oxyhyperglycemia * Diabetes mellitus Diabetes, also known as diabetes mellitus, is a group of metabolic disorders characterized by a high blood sugar level ( hyperglycemia) over a prolonged period of time. Symptoms often include frequent urination, increased thirst and increased ap ... References Endocrinology {{Symptom-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oxyhyperglycemia
Oxyhyperglycemia is a special type of impaired glucose tolerance characterized by a rapid and transient hyperglycemia (i.e. rise in blood glucose) spike after an oral intake of glucose, the peak of this spike being high enough to cause transient, symptom free glycosuria (i.e. detectable glucose in urine), but this hyperglycemia reverses rapidly and may even go to hypoglycemia in the later phase. This sharp downstroke overshooting towards hypoglycemia distinguishes this pathologic phenomenon from the artificial hyperglycemia inducible by an intravenous bolus dose of a large amount of glucose solution. Early dumping syndrome patients usually have oxyhyperglycemia associated with any meal or OGTT. The Greek root ''oxy'' means "sharp" or "pointy". The OGTT curve in this condition appears sharp and somewhat pointy (at least relative to the other forms of hyperglycemia)- hence this name.Dorlands dictionary defines oxyhyperglycemia as: :"A condition in which there is slight glycosuria and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
