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Butylated Hydroxyanisole
Butylated hydroxyanisole (BHA) is a synthetic, waxy, solid petrochemical. Its antioxidant properties have caused it to be widely used as a preservative in food, food packaging, animal feed, cosmetics, pharmaceuticals, rubber, and petroleum products. BHA has been used in food since around 1947. Chemistry BHA consists of a mixture of two isomeric organic compounds, 2-''tert''-butyl-4-hydroxyanisole and 3-''tert''-butyl-4-hydroxyanisole. It is prepared from 4-methoxyphenol and isobutylene. The conjugated aromatic ring of BHA is able to stabilize free radicals, sequestering them. By acting as free radical scavengers, further free radical reactions are prevented. Applications Since 1947, BHA has been added to edible fats and fat-containing foods for its antioxidant properties as it prevents rancidification of food which creates objectionable odors. It has been assigned the E number E320. It is often combined with a similar chemical, butylated hydroxytoluene (BHT). BHA also is ...
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Ethanol
Ethanol (abbr. EtOH; also called ethyl alcohol, grain alcohol, drinking alcohol, or simply alcohol) is an organic compound. It is an alcohol with the chemical formula . Its formula can be also written as or (an ethyl group linked to a hydroxyl group). Ethanol is a volatile, flammable, colorless liquid with a characteristic wine-like odor and pungent taste. It is a psychoactive recreational drug, the active ingredient in alcoholic drinks. Ethanol is naturally produced by the fermentation process of sugars by yeasts or via petrochemical processes such as ethylene hydration. It has medical applications as an antiseptic and disinfectant. It is used as a chemical solvent and in the synthesis of organic compounds, and as a fuel source. Ethanol also can be dehydrated to make ethylene, an important chemical feedstock. As of 2006, world production of ethanol was , coming mostly from Brazil and the U.S. Etymology ''Ethanol'' is the systematic name defined by the ...
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Simvastatin
Simvastatin, sold under the brand name Zocor among others, is a statin, a type of lipid-lowering medication. It is used along with exercise, diet, and weight loss to decrease elevated lipid levels. It is also used to decrease the risk of heart problems in those at high risk. It is taken by mouth. Common side effects include constipation, headaches, and nausea. Serious side effects may include muscle breakdown, liver problems, and increased blood sugar levels. A lower dose may be needed in people with kidney problems. There is evidence of harm to the developing baby when taken during pregnancy and it should not be used by those who are breastfeeding. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Simvastatin is made from the fungus ''Aspergillus terreus''. It was patented by Merck in 1980, and came into medical use in 1992. Simvastatin is available as a generic medication, and is on the World Health Organizati ...
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Phenols
In organic chemistry, phenols, sometimes called phenolics, are a class of chemical compounds consisting of one or more hydroxyl groups (— O H) bonded directly to an aromatic hydrocarbon group. The simplest is phenol, . Phenolic compounds are classified as simple phenols or polyphenols based on the number of phenol units in the molecule. Phenols are both synthesized industrially and produced by plants and microorganisms. Properties Acidity Phenols are more acidic than typical alcohols. The acidity of the hydroxyl group in phenols is commonly intermediate between that of aliphatic alcohols and carboxylic acids (their pKa is usually between 10 and 12). Deprotonation of a phenol forms a corresponding negative phenolate ion or phenoxide ion, and the corresponding salts are called phenolates or phenoxides (aryloxides according to the IUPAC Gold Book). Condensation with aldehydes and ketones Phenols are susceptible to Electrophilic aromatic substitutions. Condensation with form ...
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Anisole
Anisole, or methoxybenzene, is an organic compound with the formula CH3OC6H5. It is a colorless liquid with a smell reminiscent of anise seed, and in fact many of its derivatives are found in natural and artificial fragrances. The compound is mainly made synthetically and is a precursor to other synthetic compounds. It is an ether. Anisole is a standard reagent of both practical and pedagogical value. It can be prepared by the Williamson ether synthesis; sodium phenoxide is reacted with a methyl halide to yield anisole. Reactivity Anisole undergoes electrophilic aromatic substitution reaction at a faster speed than benzene, which in turn reacts more quickly than nitrobenzene. The methoxy group is an ortho/para directing group, which means that electrophilic substitution preferentially occurs at these three sites. The enhanced nucleophilicity of anisole vs. benzene reflects the influence of the methoxy group, which renders the ring more electron-rich. The methoxy group s ...
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Michael Pollan
Michael Kevin Pollan (; born February 6, 1955) is an American author and journalist, who is currently Professor of the Practice Non-Fiction and the first Lewis K. Chan Arts Lecturer at Harvard University. Concurrently, he is the Knight Professor of Science and Environmental Journalism and the director of the Knight Program in Science and Environmental Journalism at the UC Berkeley Graduate School of Journalism where in 2020 he cofounded the UC Berkeley Center for the Science of Psychedelics, in which he leads the public-education program. Pollan is best known for his books that explore the socio-cultural impacts of food, such as '' The Botany of Desire'' and '' The Omnivore's Dilemma''. Early years Pollan was born to a Jewish family on Long Island, New York. He is the son of author and financial consultant Stephen Pollan and columnist Corky Pollan. After studying at Mansfield College, Oxford through 1975, Pollan received a B.A. in English from Bennington College in 1977 and ...
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TBHQ
''tert''-Butylhydroquinone (TBHQ, tertiary butylhydroquinone) is a synthetic aromatic organic compound which is a type of phenol. It is a derivative of hydroquinone, substituted with a ''tert''-butyl group. Applications Food preservative In foods, TBHQ is used as a preservative for unsaturated vegetable oils and many edible animal fats. It does not cause discoloration even in the presence of iron, and does not change flavor or odor of the material to which it is added. It can be combined with other preservatives such as butylated hydroxyanisole (BHA). As a food additive, its E number is E319. It is added to a wide range of foods. Its primary advantage is extending storage life.''Fats and oils: formulating and processing for applications'', Richard D. O'Brien, page 168 Other In perfumery, it is used as a fixative to lower the evaporation rate and improve stability. It is used industrially as a stabilizer to inhibit autopolymerization of organic peroxides. It is used a ...
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International Agency For Research On Cancer
The International Agency for Research on Cancer (IARC; french: Centre International de Recherche sur le Cancer, CIRC) is an intergovernmental agency forming part of the World Health Organization of the United Nations. Its role is to conduct and coordinate research into the causes of cancer. It also collects and publishes surveillance data regarding the occurrence of cancer worldwide. Its IARC monographs programme identifies carcinogenic hazards and evaluates environmental causes of cancer in humans. IARC has its own governing council, and in 1965 the first members were the Federal Republic of Germany, France, Italy, the United Kingdom, and the United States of America. Today, IARC's membership has grown to 27 countries. History In late February 1963, after he experienced his spouse suffering and dying of cancer, journalist and peace activist Yves Poggioli sent a letter to Emmanuel d'Astier de la Vignerie relating his story, and urging support for the creation of an inte ...
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California
California is a state in the Western United States, located along the Pacific Coast. With nearly 39.2million residents across a total area of approximately , it is the most populous U.S. state and the 3rd largest by area. It is also the most populated subnational entity in North America and the 34th most populous in the world. The Greater Los Angeles area and the San Francisco Bay Area are the nation's second and fifth most populous urban regions respectively, with the former having more than 18.7million residents and the latter having over 9.6million. Sacramento is the state's capital, while Los Angeles is the most populous city in the state and the second most populous city in the country. San Francisco is the second most densely populated major city in the country. Los Angeles County is the country's most populous, while San Bernardino County is the largest county by area in the country. California borders Oregon to the north, Nevada and Arizona to the east, t ...
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Food And Chemical Toxicology
''Food and Chemical Toxicology'' is a peer-reviewed scientific journal covering aspects of food safety, chemical safety, and other aspects of consumer product safety. It is published by Elsevier and was established in 1963. The editor-in-chief is José L. Domingo. Abstracting and indexing The journal is abstracted and indexed in Analytical Abstracts, BIOSIS Previews, CAB International, Chemical Abstracts Service, Current Contents/Agriculture, Biology & Environmental Sciences, Current Contents/Life Sciences, Elsevier BIOBASE, EMBASE, MEDLINE/PubMed, Science Citation Index, and Scopus. According to the ''Journal Citation Reports'', it has a 2014 impact factor of 2.895, ranking it 30th out of 87 journals in the category "Toxicology" and 14th out of 123 journals in the category "Food Science & Technology". Controversies In September 2012 F&CT was the original journal which published the paper in question in the Séralini affair. In November 2013 the publisher (Elsevier) then retra ...
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Population Statistics
Demographic statistics are measures of the characteristics of, or changes to, a population. Records of births, deaths, marriages, immigration and emigration and a regular census of population provide information that is key to making sound decisions about national policy. A useful summary of such data is the population pyramid. It provides data about the sex and age distribution of the population in an accessible graphical format. Another summary is called the life table. For a ''cohort'' of persons born in the same year, it traces and projects their life experiences from birth to death. For a given cohort, the proportion expected to survive each year (or decade in an ''abridged life table'') is presented in tabular or graphical form. The ratio of males to females by age indicates the consequences of differing mortality rates on the sexes. Thus, while values above one are common for newborns, the ratio dwindles until it is well below one for the older population. Collection Nat ...
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Hamster
Hamsters are rodents (order Rodentia) belonging to the subfamily Cricetinae, which contains 19 species classified in seven genera.Fox, Sue. 2006. ''Hamsters''. T.F.H. Publications Inc. They have become established as popular small pets. The best-known species of hamster is the golden or Syrian hamster (''Mesocricetus auratus''), which is the type most commonly kept as pets. Other hamster species commonly kept as pets are the three species of dwarf hamster, Campbell's dwarf hamster (''Phodopus campbelli''), the winter white dwarf hamster (''Phodopus sungorus'') and the Roborovski hamster (''Phodopus roborovskii''). Hamsters are more crepuscular than nocturnal and, in the wild, remain underground during the day to avoid being caught by predators. They feed primarily on seeds, fruits, and vegetation, and will occasionally eat burrowing insects. Physically, they are stout-bodied with distinguishing features that include elongated cheek pouches extending to their shoulders, whi ...
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Squamous Cell Carcinoma
Squamous-cell carcinomas (SCCs), also known as epidermoid carcinomas, comprise a number of different types of cancer that begin in squamous cells. These cells form on the surface of the skin, on the lining of hollow organs in the body, and on the lining of the respiratory and digestive tracts. Common types include: * Squamous-cell skin cancer: A type of skin cancer * Squamous-cell carcinoma of the lung: A type of lung cancer * Squamous-cell thyroid carcinoma: A type of thyroid cancer * Esophageal squamous-cell carcinoma: A type of esophageal cancer * Squamous-cell carcinoma of the vagina: A type of vaginal cancer Despite sharing the name "squamous-cell carcinoma", the SCCs of different body sites can show differences in their presented symptoms, natural history, prognosis, and response to treatment. By body location Human papillomavirus infection has been associated with SCCs of the oropharynx, lung, fingers, and anogenital region. Head and neck cancer About 90% of ...
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