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Burkholderia Infection
''Burkholderia'' is a genus of Pseudomonadota whose pathogenic members include the ''Burkholderia cepacia'' complex, which attacks humans and ''Burkholderia mallei'', responsible for glanders, a disease that occurs mostly in horses and related animals; ''Burkholderia pseudomallei'', causative agent of melioidosis; and '' Burkholderia cepacia'', an important pathogen of pulmonary infections in people with cystic fibrosis (CF). ''Burkholderia'' species is also found marine environment. S.I. Paul et al. (2021) isolated and characterized ''Burkholderia cepacia'' from marine sponges of the Saint Martin's Island of the Bay of Bengal, Bangladesh. The ''Burkholderia'' (previously part of ''Pseudomonas'') genus name refers to a group of virtually ubiquitous Gram-negative, obligately aerobic, rod-shaped bacteria that are motile by means of single or multiple polar flagella, with the exception of ''Burkholderia mallei'', which is nonmotile. Members belonging to the genus do not produce s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Agar Plate
An agar plate is a Petri dish that contains a growth medium solidified with agar, used to culture microorganisms. Sometimes selective compounds are added to influence growth, such as antibiotics. Individual microorganisms placed on the plate will grow into individual colonies, each a clone genetically identical to the individual ancestor organism (except for the low, unavoidable rate of mutation). Thus, the plate can be used either to estimate the concentration of organisms in a liquid culture or a suitable dilution of that culture using a colony counter, or to generate genetically pure cultures from a mixed culture of genetically different organisms. Several methods are available to plate out cells. One technique is known as "streaking". In this technique, a drop of the culture on the end of a thin, sterile loop of wire, sometimes known as an inoculator, is streaked across the surface of the agar leaving organisms behind, a higher number at the beginning of the streak and a l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bacillus (shape)
A bacillus (), also called a bacilliform bacterium or often just a rod (when the context makes the sense clear), is a rod-shaped bacterium or archaeon. Bacilli are found in many different taxonomic groups of bacteria. However, the name ''Bacillus'', capitalized and italicized, refers to a specific genus of bacteria. The name Bacilli, capitalized but not italicized, can also refer to a less specific taxonomic group of bacteria that includes two orders, one of which contains the genus ''Bacillus''. When the word is formatted with lowercase and not italicized, 'bacillus', it will most likely be referring to shape and not to the genus at all. Bacilliform bacteria are also often simply called rods when the bacteriologic context is clear. Bacilli usually divide in the same plane and are solitary, but can combine to form diplobacilli, streptobacilli, and palisades. * Diplobacilli: Two bacilli arranged side by side with each other. * Streptobacilli: Bacilli arranged in chains. * Coccobac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Paraburkholderia
''Paraburkholderia'' is a genus of Pseudomonadota that are gram negative, slightly curved rods that are motile by means of flagella. They have been reported to colonize endophytic tissues of hybrid spruce (Picea glauca x engelmannii) and lodgepole pine with a strong potential to perform biological nitrogen fixation and plant growth promotion. Unlike ''Burkholderia'' species, ''Paraburkholderia'' members are not commonly associated with human infection. ''Paraburkholderia'' members form a monophyletic clade within the Burkholderiaceae family, which is what prompted their distinction as a genus independent from ''Burkholderia'' species, in combination with the finding of robust conserved signature indels which are unique to ''Paraburkholderia'' species, and are lacking in members of the genus ''Burkholderia''. These CSIs distinguish the genus from all other bacteria. Additionally, the CSIs that were found to be shared by ''Burkholderia'' species are absent in ''Paraburkholderia'' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cornell University
Cornell University is a private statutory land-grant research university based in Ithaca, New York. It is a member of the Ivy League. Founded in 1865 by Ezra Cornell and Andrew Dickson White, Cornell was founded with the intention to teach and make contributions in all fields of knowledge—from the classics to the sciences, and from the theoretical to the applied. These ideals, unconventional for the time, are captured in Cornell's founding principle, a popular 1868 quotation from founder Ezra Cornell: "I would found an institution where any person can find instruction in any study." Cornell is ranked among the top global universities. The university is organized into seven undergraduate colleges and seven graduate divisions at its main Ithaca campus, with each college and division defining its specific admission standards and academic programs in near autonomy. The university also administers three satellite campuses, two in New York City and one in Education City, Qatar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Walter H
Walter may refer to: People * Walter (name), both a surname and a given name * Little Walter, American blues harmonica player Marion Walter Jacobs (1930–1968) * Gunther (wrestler), Austrian professional wrestler and trainer Walter Hahn (born 1987), who previously wrestled as "Walter" * Walter, standard author abbreviation for Thomas Walter (botanist) ( – 1789) Companies * American Chocolate, later called Walter, an American automobile manufactured from 1902 to 1906 * Walter Energy, a metallurgical coal producer for the global steel industry * Walter Aircraft Engines, Czech manufacturer of aero-engines Films and television * ''Walter'' (1982 film), a British television drama film * Walter Vetrivel, a 1993 Tamil crime drama film * ''Walter'' (2014 film), a British television crime drama * ''Walter'' (2015 film), an American comedy-drama film * ''Walter'' (2020 film), an Indian crime drama film * ''W*A*L*T*E*R'', a 1984 pilot for a spin-off of the TV series ''M*A*S*H'' * ''W ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biological Warfare
Biological warfare, also known as germ warfare, is the use of biological toxins or infectious agents such as bacteria, viruses, insects, and fungi with the intent to kill, harm or incapacitate humans, animals or plants as an act of war. Biological weapons (often termed "bio-weapons", "biological threat agents", or "bio-agents") are living organisms or replicating entities ( ''i.e.'' viruses, which are not universally considered "alive"). Entomological (insect) warfare is a subtype of biological warfare. Offensive biological warfare is prohibited under customary international humanitarian law and several international treaties. In particular, the 1972 Biological Weapons Convention (BWC) bans the development, production, acquisition, transfer, stockpiling and use of biological weapons. Therefore, the use of biological agents in armed conflict is a war crime. In contrast, defensive biological research for prophylactic, protective or other peaceful purposes is not proh ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antimicrobial Resistance
Antimicrobial resistance (AMR) occurs when microbes evolve mechanisms that protect them from the effects of antimicrobials. All classes of microbes can evolve resistance. Fungi evolve antifungal resistance. Viruses evolve antiviral resistance. Protozoa evolve antiprotozoal resistance, and bacteria evolve antibiotic resistance. Those bacteria that are considered extensively drug resistant (XDR) or totally drug-resistant (TDR) are sometimes called "superbugs".A.-P. Magiorakos, A. Srinivasan, R. B. Carey, Y. Carmeli, M. E. Falagas, C. G. Giske, S. Harbarth, J. F. Hinndler ''et al''Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria... Clinical Microbiology and Infection, Vol 8, Iss. 3 first published 27 July 2011 ia Wiley Online Library Retrieved 28 August 2020 Although antimicrobial resistance is a naturally-occurring process, it is often the result of improper usage of the drugs and management of the infections. Antibiotic resistance is a major subset o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anti-hemB RNA Motif
The anti-hemB RNA motif is a conserved RNA structure that was found in all known bacteria in the genus ''Burkholderia'', and in a variety of other betaproteobacteria. The anti-hemB RNA motif consists primarily of two stem-loops, followed by a predicted rho-independent transcription termination stem-loop. As anti-hemB RNAs are generally not located in a 5' UTR, the RNAs are presumed to be non-coding RNAs. The terminator stem-loop implies that anti-hemB RNAs are transcribed as independent molecules. The name "anti-hemB" is to distinguish the motif from its reverse complement, which was called the "hemB" motif, a motif that is often in the apparent 5' UTRs of ''hemB'' genes. It was considered ambiguous as to which of these orientations is correct, as both directions exhibit covariation (see secondary structure prediction), and both fold into plausible RNA structures. However, the anti-hemB was judged the more likely orientation, because it had fewer A-C base pair A base pair ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polychlorinated Biphenyl
Polychlorinated biphenyls (PCBs) are highly carcinogenic chemical compounds, formerly used in industrial and consumer products, whose production was banned in the United States by the Toxic Substances Control Act in 1979 and internationally by the Stockholm Convention on Persistent Organic Pollutants in 2001. They are organic chlorine compounds with the formula C12 H10−''x'' Cl''x''; they were once widely used in the manufacture of carbonless copy paper, as heat transfer fluids, and as dielectric and coolant fluids for electrical equipment. Because of their longevity, PCBs are still widely in use, even though their manufacture has declined drastically since the 1960s, when a host of problems were identified. With the discovery of PCBs' environmental toxicity, and classification as persistent organic pollutants, their production was banned by United States federal law in 1978, and by the Stockholm Convention on Persistent Organic Pollutants in 2001. The International Agency ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chronic Granulomatous Disease
Chronic granulomatous disease (CGD), also known as Bridges–Good syndrome, chronic granulomatous disorder, and Quie syndrome, is a diverse group of hereditary diseases in which certain cells of the immune system have difficulty forming the reactive oxygen compounds (most importantly the superoxide radical due to defective phagocyte NADPH oxidase) used to kill certain ingested pathogens. This leads to the formation of granulomas in many organs. CGD affects about 1 in 200,000 people in the United States, with about 20 new cases diagnosed each year. This condition was first discovered in 1950 in a series of 4 boys from Minnesota, and in 1957 it was named "a fatal granulomatosus of childhood" in a publication describing their disease. The underlying cellular mechanism that causes chronic granulomatous disease was discovered in 1967, and research since that time has further elucidated the molecular mechanisms underlying the disease. Bernard Babior made key contributions in linking the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pathogens
In biology, a pathogen ( el, πάθος, "suffering", "passion" and , "producer of") in the oldest and broadest sense, is any organism or agent that can produce disease. A pathogen may also be referred to as an infectious agent, or simply a germ. The term ''pathogen'' came into use in the 1880s. Typically, the term ''pathogen'' is used to describe an ''infectious'' microorganism or agent, such as a virus, bacterium, protozoan, prion, viroid, or fungus. Small animals, such as helminths and insects, can also cause or transmit disease. However, these animals are usually referred to as parasites rather than pathogens. The scientific study of microscopic organisms, including microscopic pathogenic organisms, is called microbiology, while parasitology refers to the scientific study of parasites and the organisms that host them. There are several pathways through which pathogens can invade a host. The principal pathways have different episodic time frames, but soil has the longest ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polyhydroxybutyrate
Polyhydroxybutyrate (PHB) is a polyhydroxyalkanoate (PHA), a polymer belonging to the polyesters class that are of interest as bio-derived and biodegradable plastics. The poly-3-hydroxybutyrate (P3HB) form of PHB is probably the most common type of polyhydroxyalkanoate, but other polymers of this class are produced by a variety of organisms: these include poly-4-hydroxybutyrate (P4HB), polyhydroxyvalerate (PHV), polyhydroxyhexanoate (PHH), polyhydroxyoctanoate (PHO) and their copolymers. Biosynthesis PHB is produced by microorganisms (such as '' Cupriavidus necator'', '' Methylobacterium rhodesianum'' or ''Bacillus megaterium'') apparently in response to conditions of physiological stress; mainly conditions in which nutrients are limited. The polymer is primarily a product of carbon assimilation (from glucose or starch) and is employed by microorganisms as a form of energy storage molecule to be metabolized when other common energy sources are not available. Microbial biosynthe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
