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Buckley's
W. K. Buckley Limited is a corporation operating in Canada that manufactures medicines for health problems such as the common cold. They also have children's medicine which are sold under the brand Jack & Jill. The company is located in Mississauga, Ontario. It is a subsidiary of Novartis. The company was founded in 1919 by William Knapp Buckley (1890 - 1978), In 1978, after W. K. Buckley's death, his adopted son Frank Buckley became the president of the company. In the mid-1980s, Frank became spokesperson promoting the "It Tastes Awful. And It Works." slogan, which became very successful. Novartis purchased ownership of the Buckley's brand and formulas in 2002. The remaining Buckley company, William Knapp Limited, which provides Marketing consultancy services, is led by David Rieger, the Vice President of Marketing reporting directly to Frank Buckley. Prior to this position, Mr. Rieger held a number of other senior positions with the Buckley organization and with the Novartis c ...
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Francis Buckley
Francis "Frank" C. Buckley, (April 8, 1921 – February 1, 2016) was president and spokesperson for the Buckley's company, founded by his adoptive father W.K. Buckley, in 1920. In 2005, the company was sold to Novartis. In 2003, he was made a Member of the Order of Canada for being "an inspiring example of how one can positively influence the lives of many". Life Buckley was born in Toronto, Ontario, Canada in 1921 and adopted by William Buckley, who had founded Buckley's Company in 1920; one year prior to Francis' adoption. He attended St. Michael's College School and graduated from the University of Toronto in 1942 with a bachelor's degree in commerce and finance. Shortly after graduating from college Buckley enlisted in the Royal Navy Fleet Air Arm as a carrier-based fighter pilot and served in World War II World War II or the Second World War, often abbreviated as WWII or WW2, was a world war that lasted from 1939 to 1945. It involved the vast majority o ...
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Novartis
Novartis AG is a Swiss-American multinational pharmaceutical corporation based in Basel, Switzerland and Cambridge, Massachusetts, United States (global research).name="novartis.com">https://www.novartis.com/research-development/research-locations It is one of the largest pharmaceutical companies in the world. Novartis manufactures the drugs clozapine (Clozaril), diclofenac (Voltaren; sold to GlaxoSmithKline in 2015 deal), carbamazepine (Tegretol), valsartan (Diovan), imatinib mesylate (Gleevec/Glivec), cyclosporine (Neoral/Sandimmune), letrozole (Femara), methylphenidate (Ritalin; production ceased 2020), terbinafine (Lamisil), deferasirox (Exjade), and others. In March 1996, the companies Ciba-Geigy and Sandoz merged to form Novartis; the pharmaceutical and agrochemical divisions of both companies formed Novartis as an independent entity. Other Ciba-Geigy and Sandoz businesses were sold, or, like Ciba Specialty Chemicals, spun off as independent companies. The Sandoz ...
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Ammonium Carbonate
Ammonium carbonate is a salt with the chemical formula (NH4)2CO3. Since it readily degrades to gaseous ammonia and carbon dioxide upon heating, it is used as a leavening agent and also as smelling salt. It is also known as baker's ammonia and is a predecessor to the more modern leavening agents baking soda and baking powder. It is a component of what was formerly known as sal volatile and salt of hartshorn, and produces a pungent smell when baked. Production Ammonium carbonate is produced by combining carbon dioxide and aqueous ammonia. About 80,000 tons/year were produced as of 1997. An orthorhombic monohydrate is known. It crystallizes in an ammonia solution exposed in a carbon dioxide-rich atmosphere. Decomposition Ammonium carbonate slowly decomposes at standard temperature and pressure through two pathways. Thus any initially pure sample of ammonium carbonate will soon become a mixture including various byproducts. Ammonium carbonate can spontaneously decompose into ammo ...
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Corporation
A corporation is an organization—usually a group of people or a company—authorized by the state to act as a single entity (a legal entity recognized by private and public law "born out of statute"; a legal person in legal context) and recognized as such in law for certain purposes. Early incorporated entities were established by charter (i.e. by an ''ad hoc'' act granted by a monarch or passed by a parliament or legislature). Most jurisdictions now allow the creation of new corporations through registration. Corporations come in many different types but are usually divided by the law of the jurisdiction where they are chartered based on two aspects: by whether they can issue stock, or by whether they are formed to make a profit. Depending on the number of owners, a corporation can be classified as ''aggregate'' (the subject of this article) or '' sole'' (a legal entity consisting of a single incorporated office occupied by a single natural person). One of the most at ...
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Cough
A cough is a sudden expulsion of air through the large breathing passages that can help clear them of fluids, irritants, foreign particles and microbes. As a protective reflex, coughing can be repetitive with the cough reflex following three phases: an inhalation, a forced exhalation against a closed glottis, and a violent release of air from the lungs following opening of the glottis, usually accompanied by a distinctive sound. Frequent coughing usually indicates the presence of a disease. Many viruses and bacteria benefit, from an evolutionary perspective, by causing the host to cough, which helps to spread the disease to new hosts. Most of the time, irregular coughing is caused by a respiratory tract infection but can also be triggered by choking, smoking, air pollution, asthma, gastroesophageal reflux disease, post-nasal drip, chronic bronchitis, lung tumors, heart failure and medications such as angiotensin-converting-enzyme inhibitors (ACE inhibitors). Treatment sho ...
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Antitussive
Cold medicines are a group of medications taken individually or in combination as a treatment for the symptoms of the common cold and similar conditions of the upper respiratory tract. The term encompasses a broad array of drugs, including analgesics, antihistamines and decongestants, among many others. It also includes drugs which are marketed as cough suppressants or antitussives, but their effectiveness in reducing cough symptoms is unclear or minimal. While they have been used by 10% of American children in any given week, they are not recommended in Canada or the United States in children six years or younger because of lack of evidence showing effect and concerns of harm. In 2020, one version containing codeine and guaifenesin was the 377th most commonly prescribed medication in the United States with more than 400thousand prescriptions. Types There are a number of different cough and cold medications, which may be used for various coughing symptoms. The commercially ...
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Capsicum
''Capsicum'' () is a genus of flowering plants in the nightshade family Solanaceae, native to the Americas, cultivated worldwide for their chili pepper or bell pepper fruit. Etymology and names The generic name may come from Latin , meaning 'box', presumably alluding to the pods; or possibly from the Greek word , 'to gulp'. The name "pepper" comes from the similarity of piquance (spiciness or "heat") of the flavor to that of black pepper, '' Piper nigrum'', although there is no botanical relationship with it or with Sichuan pepper. The original term, ''chilli'' (now ''chile'' in Mexico) came from the Nahuatl word ''chīlli'', denoting a larger ''Capsicum'' variety cultivated at least since 3000 BC, as evidenced by remains found in pottery from Puebla and Oaxaca. Different varieties were cultivated in South America, where they are known as ''ajíes'' (singular ''ají''), from the Quechua term for ''Capsicum''. The fruit (technically berries in the strict botanic ...
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Tincture
A tincture is typically an extract of plant or animal material dissolved in ethanol (ethyl alcohol). Solvent concentrations of 25–60% are common, but may run as high as 90%.Groot Handboek Geneeskrachtige Planten by Geert Verhelst In chemistry, a tincture is a solution that has ethanol as its solvent. In herbal medicine, alcoholic tinctures are made with various ethanol concentrations, which should be at least 20% alcohol for preservation purposes. Other solvents for producing tinctures include vinegar, glycerol (also called glycerine), diethyl ether and propylene glycol, not all of which can be used for internal consumption. Ethanol has the advantage of being an excellent solvent for both acidic and basic (alkaline) constituents. A tincture using glycerine is called a glycerite. Glycerine is generally a poorer solvent than ethanol. Vinegar, being acidic, is a better solvent for obtaining alkaloids but a poorer solvent for acidic components. For individuals who choose not t ...
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Pine Oil
Pine oil is an essential oil obtained from a variety of species of pine, particularly ''Pinus sylvestris''. Typically, parts of the trees that are not used for lumber - stumps, etc. - are ground and subjected to steam distillation. As of 1995, synthetic pine oil was the "biggest single turpentine derivative." Synthetic pine oils accounted for 90% of sales as of 2000. Composition Pine oil is a higher boiling fraction from turpentine. Both synthetic and natural pine oil consists mainly of α-terpineol, a C10 alcohol (b.p. 214–217 °C).''Merck Index'', 11th Edition, 7416. p. 1182 The detailed composition of natural pine oil depends on many factors, such as the species of the host plant. Synthetic pine oil is obtained by treating pinene with water in the presence of a catalytic amount of sulfuric acid. This treatment results in hydration of the alkene and rearrangement of the pinene skeleton, yielding terpineols. Uses Industrially, pine oil was once used in froth flotatio ...
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Balsam Fir
''Abies balsamea'' or balsam fir is a North American fir, native to most of eastern and central Canada (Newfoundland west to central Alberta) and the northeastern United States (Minnesota east to Maine, and south in the Appalachian Mountains to West Virginia). Description Balsam fir is a small to medium-size evergreen tree typically tall, occasionally reaching a height of . The narrow conic crown consists of dense, dark-green leaves. The bark on young trees is smooth, grey, and with resin blisters (which tend to spray when ruptured), becoming rough and fissured or scaly on old trees. The leaves are flat and needle-like, long, dark green above often with a small patch of stomata near the tip, and two white stomatal bands below, and a slightly notched tip. They are arranged spirally on the shoot, but with the leaf bases twisted so that the leaves appear to be in two more-or-less horizontal rows on either side of the shoot. The needles become shorter and thicker the higher they a ...
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Menthol
Menthol is an organic compound, more specifically a monoterpenoid, made synthetically or obtained from the oils of corn mint, peppermint, or other mints. It is a waxy, clear or white crystalline substance, which is solid at room temperature and melts slightly above. The main form of menthol occurring in nature is (−)-menthol, which is assigned the (1''R'',2''S'',5''R'') configuration. Menthol has local anesthetic and counterirritant qualities, and it is widely used to relieve minor throat irritation. Menthol also acts as a weak κ-opioid receptor agonist. Structure Natural menthol exists as one pure stereoisomer, nearly always the (1''R'',2''S'',5''R'') form (bottom left corner of the diagram below). The eight possible stereoisomers are: : In the natural compound, the isopropyl group is in the '' trans'' orientation to both the methyl and hydroxyl groups. Thus, it can be drawn in any of the ways shown: : The (+)- and (−)- enantiomers of menthol are the most stab ...
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