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Bubble Oxygenator
A bubble oxygenator is an early implementation of the oxygenator used for cardiopulmonary bypass. It has since been supplanted by the membrane oxygenator as a result of advances in material science. Some continue to promote it as a low-cost alternative allowing greater self-sufficiency. History Cardiac surgery, Open-heart surgery developed rapidly beginning in the 1950s, and many methods were developed for oxygenating blood outside the body. A bubble oxygenator was introduced in 1950 by Clark, Gollan, and Gupta. The method faced initial skepticism but in 1956 the University of Minnesota's Richard DeWall, De-Wall-C. Walton Lillehei, Lillehei bubble oxygenator was demonstrated to be relatively simple, inexpensive, and easy to operate. The device faced competition from membrane oxygenators, which arrived within the same decade and were found to provide better oxygenation for periods over eight hours, and other advantages beyond six hours. However, most cardiac surgery, open-heart op ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oxygenator
An oxygenator is a medical device that is capable of exchanging oxygen and carbon dioxide in the blood of human patient during surgical procedures that may necessitate the interruption or cessation of blood flow in the body, a critical organ or great blood vessel. These organs can be the heart, lungs or liver, while the great vessels can be the aorta, pulmonary artery, pulmonary veins or vena cava. Usage An oxygenator is typically utilized by a perfusionist in cardiac surgery in conjunction with the heart-lung machine. However, oxygenators can also be utilized in extracorporeal membrane oxygenation in neonatal intensive care units by nurses. For most cardiac operations such as coronary artery bypass grafting, the cardiopulmonary bypass is performed using a heart-lung machine (or cardiopulmonary bypass machine). The heart-lung machine serves to replace the work of the heart during the open bypass surgery. The machine replaces both the heart's pumping action and the lungs' gas exc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cardiopulmonary Bypass
Cardiopulmonary bypass (CPB) is a technique in which a machine temporarily takes over the function of the heart and lungs during surgery, maintaining the circulation of blood and oxygen to the body. The CPB pump itself is often referred to as a heart–lung machine or "the pump". Cardiopulmonary bypass pumps are operated by perfusionists. CPB is a form of extracorporeal circulation. Extracorporeal membrane oxygenation is generally used for longer-term treatment. CPB mechanically circulates and oxygenates blood for the body while bypassing the heart and lungs. It uses a heart–lung machine to maintain perfusion to other body organs and tissues while the surgeon works in a bloodless surgical field. The surgeon places a cannula in the right atrium, vena cava, or femoral vein to withdraw blood from the body. Venous blood is removed from the body by the cannula and then filtered, cooled or warmed, and oxygenated before it is returned to the body by a mechanical pump. The cannula used ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Membrane Oxygenator
A membrane oxygenator is a device used to add oxygen to, and remove carbon dioxide from the blood. It can be used in two principal modes: to imitate the function of the lungs in cardiopulmonary bypass (CPB), and to oxygenate blood in longer term life support, termed extracorporeal membrane oxygenation (ECMO). A membrane oxygenator consists of a thin gas-permeable membrane separating the blood and gas flows in the CPB circuit; oxygen diffuses from the gas side into the blood, and carbon dioxide diffuses from the blood into the gas for disposal. History The history of the oxygenator, or artificial lung, dates back to 1885, with the first demonstration of a disc oxygenator, on which blood was exposed to the atmosphere on rotating discs by Von Frey and Gruber. These pioneers noted the dangers of blood streaming, foaming and clotting. In the 1920s and 30s, research into developing extracorporeal oxygenation continued. Working independently, Brukhonenko in the USSR and John Heysha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cardiac Surgery
Cardiac surgery, or cardiovascular surgery, is surgery on the heart or great vessels performed by cardiac surgeons. It is often used to treat complications of ischemic heart disease (for example, with coronary artery bypass grafting); to correct congenital heart disease; or to treat valvular heart disease from various causes, including endocarditis, Rheumatic fever, rheumatic heart disease, and atherosclerosis. It also includes heart transplantation. History 19th century The earliest operations on the pericardium (the sac that surrounds the heart) took place in the 19th century and were performed by Francisco Romero (surgeon), Francisco Romero (1801) in the city of Almería (Spain), Dominique Jean Larrey (1810), Henry Dalton (1891), and Daniel Hale Williams (1893). The first surgery on the heart itself was performed by Axel Cappelen on 4 September 1895 at Rikshospitalet in Kristiania, now Oslo. Cappelen ligature (medicine), ligated a bleeding coronary circulation, coronary ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Richard DeWall
Richard A. DeWall (1926-2016), was an American cardiothoracic surgeon who in 1955 created the first workable, portable bubble oxygenator that removed bubbles, thus avoiding gas embolism during cardiopulmonary bypass. Later, he wrote the original plans for what became the Wright State University School of Medicine. Early life and education Richard Alison DeWall was born on 16 December 1926 to Grace Gardner and Herman Harvey DeWall in Appleton, Minnesota. After serving in the U.S. Navy until October 1945, he graduated from the University of Minnesota in 1949 and subsequently gained his MD in 1953. Career John Gibbon had invented the heart-lung bypass machine and performed the first repair of the heart from the inside of the heart, using extracorporal perfusion in 1953. In 1955, John W. Kirklin, who was a surgeon also researching heart-lung machines, was successful in using Gibbon’s modified heart-lung machine via a pump-oxygenator. Soon C. Walton Lillehei, who worked nearb ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cardiac Surgery
Cardiac surgery, or cardiovascular surgery, is surgery on the heart or great vessels performed by cardiac surgeons. It is often used to treat complications of ischemic heart disease (for example, with coronary artery bypass grafting); to correct congenital heart disease; or to treat valvular heart disease from various causes, including endocarditis, Rheumatic fever, rheumatic heart disease, and atherosclerosis. It also includes heart transplantation. History 19th century The earliest operations on the pericardium (the sac that surrounds the heart) took place in the 19th century and were performed by Francisco Romero (surgeon), Francisco Romero (1801) in the city of Almería (Spain), Dominique Jean Larrey (1810), Henry Dalton (1891), and Daniel Hale Williams (1893). The first surgery on the heart itself was performed by Axel Cappelen on 4 September 1895 at Rikshospitalet in Kristiania, now Oslo. Cappelen ligature (medicine), ligated a bleeding coronary circulation, coronary ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Microporous Material
A microporous material is a material containing pores with diameters less than 2 nm. Examples of microporous materials include zeolites and metal-organic frameworks. Porous materials are classified into several kinds by their size. The recommendations of a panel convened by the International Union of Pure and Applied Chemistry (IUPAC) are: See page 1745. *Microporous materials have pore diameters of less than 2 nm. *Mesoporous materials have pore diameters between 2 nm and 50 nm. *Macroporous materials have pore diameters of greater than 50 nm. Micropores may be defined differently in other contexts. For example, in the context of porous aggregations such as soil, micropores are defined as cavities with sizes less than 30 μm. Uses in laboratories Microporous materials are often used in laboratory environments to facilitate contaminant-free exchange of gases. Mold spores, bacteria, and other airborne contaminants will become trapped, while gases are ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
