Bruce Colston Trapnell Jr
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Bruce Colston Trapnell Jr
Bruce Colston Trapnell Jr. (born 1982) is an assistant professor in the Department of Genome Sciences at the University of Washington. He was awarded the Overton Prize The ISCB Overton Prize is a Awards in Bioinformatics and Computational Biology, computational biology prize awarded annually for outstanding accomplishment by a scientist in the early to mid stage of his or her career. Laureates have made significan ... by the International Society for Computational Biology (ISCB) for “outstanding accomplishment in the early to mid stage of his career” in 2018. References {{DEFAULTSORT:Trapnell, Cole Living people American bioinformaticians Overton Prize winners 1982 births University of Washington faculty ...
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Intelligent Systems For Molecular Biology
Intelligent Systems for Molecular Biology (ISMB) is an annual academic conference on the subjects of bioinformatics and computational biology organised by the International Society for Computational Biology (ISCB). The principal focus of the conference is on the development and application of advanced computational methods for biological problems. The conference has been held every year since 1993 and has grown to become one of the largest and most prestigious meetings in these fields, hosting over 2,000 delegates in 2004. From the first meeting, ISMB has been held in locations worldwide; since 2007, meetings have been located in Europe and North America in alternating years. Since 2004, European meetings have been held jointly with the European Conference on Computational Biology (ECCB). The main ISMB conference is usually held over three days and consists of presentations, poster sessions and keynote talks. Most presentations are given in multiple parallel tracks; however, key ...
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TopHat (bioinformatics)
TopHat is an open-source bioinformatics tool for the throughput alignment of shotgun cDNA sequencing reads generated by transcriptomics technologies (e.g. RNA-Seq) using Bowtie first and then mapping to a reference genome to discover RNA splice sites ''de novo''. TopHat aligns RNA-Seq reads to mammalian-sized genomes. History TopHat was originally developed in 2009 by Cole Trapnell, Lior Pachter and Steven Salzberg at the Center for Bioinformatics and Computational Biology at the University of Maryland, College Park and at the Mathematics Department, UC Berkeley. TopHat2 was a collaborative effort of Daehwan Kim and Steven Salzberg, initially at the University of Maryland, College Park and later at the Center for Computational Biology at Johns Hopkins University. Kim re-wrote some of Trapnell's original TopHat code in C++ to make it much faster, and added many heuristics to improve its accuracy, in a collaboration with Cole Trapnell and others. Kim and Salzberg also developed TopH ...
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Overton Prize Winners
Overton may refer to: Places Canada * Overton, Nova Scotia United Kingdom * Overton, Aberdeen, a location * Overton, Frodsham, a location in Cheshire * Overton, Malpas, Cheshire * Overton, Gloucestershire, a hamlet in the parish of Arlingham * Overton, Greenock, Inverclyde * Overton, Hampshire * Overton, Lancashire * Overton, North Yorkshire * Overton, Shropshire * Overton, Staffordshire, a location * Overton, Swansea * Overton, West Yorkshire * Overton, a settlement in Cunninghamhead, Perceton and Annick Lodge, Ayrshire * Overton, an area of Halfway, South Lanarkshire * Overton Down, an experimental archaeology site * Overton or Overton-on-Dee, Wrexham * Cold Overton, Leicestershire * Market Overton, Rutland * West Overton, Wiltshire United States * Overton, Missouri * Overton, Nebraska * Overton, Nevada * Overton, Ohio * Overton, Texas * Overton, Virginia * Overton County, Tennessee * Overton Township, Bradford County, Pennsylvania * West Overton, Pennsylvania Other ...
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American Bioinformaticians
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer * B ...
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Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ...
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International Society For Computational Biology
The International Society for Computational Biology (ISCB) is a scholarly society for researchers in computational biology and bioinformatics. The society was founded in 1997 to provide a stable financial home for the Intelligent Systems for Molecular Biology (ISMB) conference and has grown to become a larger society working towards advancing understanding of living systems through computation and for communicating scientific advances worldwide. In addition to ISMB, the society also organizes a growing number of smaller, more regionally or topically focused conferences and presents a number of annual scientific achievement awards, including the Overton Prize and the ISCB Senior Scientist Awards. Overview Society membership reflects commitment toward the advancement of computational biology. The ISCB is an international non-profit organization whose members come from the global bioinformatics and computational biology communities. The ISCB serves its global membership by providing ...
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Genomics
Genomics is an interdisciplinary field of biology focusing on the structure, function, evolution, mapping, and editing of genomes. A genome is an organism's complete set of DNA, including all of its genes as well as its hierarchical, three-dimensional structural configuration. In contrast to genetics, which refers to the study of ''individual'' genes and their roles in inheritance, genomics aims at the collective characterization and quantification of ''all'' of an organism's genes, their interrelations and influence on the organism. Genes may direct the production of proteins with the assistance of enzymes and messenger molecules. In turn, proteins make up body structures such as organs and tissues as well as control chemical reactions and carry signals between cells. Genomics also involves the sequencing and analysis of genomes through uses of high throughput DNA sequencing and bioinformatics to assemble and analyze the function and structure of entire genomes. Advances in ...
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Overton Prize
The ISCB Overton Prize is a Awards in Bioinformatics and Computational Biology, computational biology prize awarded annually for outstanding accomplishment by a scientist in the early to mid stage of his or her career. Laureates have made significant contribution to the field of computational biology either through research, education, service, or a combination of the three. The prize was established by the International Society for Computational Biology (ISCB) in memory of a major contributor to the field of bioinformatics and member of the ISCB Board of Directors who died unexpectedly in 2000. The Overton Prize is traditionally awarded at the Intelligent Systems for Molecular Biology (ISMB) conference. Laureates Laureates include *2022 - *2021 - Barbara Engelhardt *2020 - *2019 - Christophe Dessimoz *2018 - Cole Trapnell *2017 - Christoph Bock *2016 - Debora Marks *2015 - Curtis Huttenhower *2014 - Dana Pe'er *2013 - Gonçalo Abecasis *2012 - Ziv Bar-Joseph *2011 - Olga Troya ...
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Bowtie (sequence Analysis)
Bowtie is a software package commonly used for sequence alignment and sequence analysis in bioinformatics. The source code for the package is distributed freely and compiled binaries are available for Linux, macOS and Windows platforms. As of 2017, the ''Genome Biology'' paper describing the original Bowtie method has been cited more than 11,000 times. Bowtie is open-source software and is currently maintained by Johns Hopkins University. History The Bowtie sequence aligner was originally developed by Ben Langmead ''et al.'' at the University of Maryland in 2009. The aligner is typically used with short reads and a large reference genome, or for whole genome analysis. Bowtie is promoted as "an ultrafast, memory-efficient short aligner for short DNA sequences." The speed increase of Bowtie is partly due to implementing the Burrows–Wheeler transform for aligning, which reduces the memory footprint (typically to around 2.2GB for the human genome); a similar method is used by t ...
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Transcriptomics
Transcriptomics technologies are the techniques used to study an organism's transcriptome, the sum of all of its RNA transcripts. The information content of an organism is recorded in the DNA of its genome and expressed through transcription. Here, mRNA serves as a transient intermediary molecule in the information network, whilst non-coding RNAs perform additional diverse functions. A transcriptome captures a snapshot in time of the total transcripts present in a cell. Transcriptomics technologies provide a broad account of which cellular processes are active and which are dormant. A major challenge in molecular biology is to understand how a single genome gives rise to a variety of cells. Another is how gene expression is regulated. The first attempts to study whole transcriptomes began in the early 1990s. Subsequent technological advances since the late 1990s have repeatedly transformed the field and made transcriptomics a widespread discipline in biological sciences. There ar ...
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Lior Pachter
Lior Samuel Pachter is a computational biologist. He works at the California Institute of Technology, where he is the Bren Professor of Computational Biology. He has widely varied research interests including genomics, combinatorics, computational geometry, machine learning, scientific computing, and statistics.. Early life and education Pachter was born in Israel and grew up in South Africa. He earned a bachelor's degree in mathematics from the California Institute of Technology in 1994. He completed his doctorate in mathematics from the Massachusetts Institute of Technology in 1999, supervised by Bonnie Berger, with Eric Lander and Daniel Kleitman as co-advisors. Career and research Pachter was with the University of California, Berkeley faculty from 1999 to 2018 and was given the Sackler Chair in 2012. As well as for his technical contributions, Pachter is known for using new media to promote open science and for a thought experiment he posted on his blog according to which ...
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Steven Salzberg
Steven Lloyd Salzberg (born 1960) is an American computational biologist and computer scientist who is a Bloomberg Distinguished Professor of Biomedical Engineering, Computer Science, and Biostatistics at Johns Hopkins University, where he is also Director of the Center for Computational Biology. Early life and education Salzberg was born in 1960 as one of four children to Herman Salzberg, a Distinguished Professor Emeritus of Psychology, and Adele Salzberg, a retired school teacher. Salzberg did his undergraduate studies at Yale University where he received his Bachelor of Arts degree in English in 1980. In 1981 he returned to Yale, and he received his Master of Science and Master of Philosophy degrees in Computer Science in 1982 and 1984, respectively. After several years in a startup company, he enrolled at Harvard University, where he earned a Ph.D. in Computer Science in 1989. Career After earning his Ph.D., Salzberg joined Johns Hopkins University as an Assistant Professo ...
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