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Blue Brain
The Blue Brain Project is a Swiss brain research initiative that aims to create a digital reconstruction of the mouse brain. The project was founded in May 2005 by the Brain and Mind Institute of ''École Polytechnique Fédérale de Lausanne'' (EPFL) in Switzerland. Its mission is to use biologically-detailed digital reconstructions and simulations of the mammalian brain to identify the fundamental principles of brain structure and function. The project is headed by the founding director Henry Markram—who also launched the European Human Brain Project—and is co-directed by Felix Schürmann, Adriana Salvatore and Sean Hill. Using a Blue Gene supercomputer running Michael Hines's NEURON, the simulation involves a biologically realistic model of neurons and an empirically reconstructed model connectome. There are a number of collaborations, including the Cajal Blue Brain, which is coordinated by the Supercomputing and Visualization Center of Madrid (CeSViMa), and others run by ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brain And Mind Institute
A brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals. It is located in the head, usually close to the sensory organs for senses such as vision. It is the most complex organ in a vertebrate's body. In a human, the cerebral cortex contains approximately 14–16 billion neurons, and the estimated number of neurons in the cerebellum is 55–70 billion. Each neuron is connected by synapses to several thousand other neurons. These neurons typically communicate with one another by means of long fibers called axons, which carry trains of signal pulses called action potentials to distant parts of the brain or body targeting specific recipient cells. Physiologically, brains exert centralized control over a body's other organs. They act on the rest of the body both by generating patterns of muscle activity and by driving the secretion of chemicals called hormones. This centralized control allows rapid and coordinated responses ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Synapse
In the nervous system, a synapse is a structure that permits a neuron (or nerve cell) to pass an electrical or chemical signal to another neuron or to the target effector cell. Synapses are essential to the transmission of nervous impulses from one neuron to another. Neurons are specialized to pass signals to individual target cells, and synapses are the means by which they do so. At a synapse, the plasma membrane of the signal-passing neuron (the ''presynaptic'' neuron) comes into close apposition with the membrane of the target (''postsynaptic'') cell. Both the presynaptic and postsynaptic sites contain extensive arrays of Molecular biology, molecular machinery that link the two membranes together and carry out the signaling process. In many synapses, the presynaptic part is located on an axon and the postsynaptic part is located on a dendrite or soma (biology), soma. Astrocytes also exchange information with the synaptic neurons, responding to synaptic activity and, in turn, r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
GitHub
GitHub, Inc. () is an Internet hosting service for software development and version control using Git. It provides the distributed version control of Git plus access control, bug tracking, software feature requests, task management, continuous integration, and wikis for every project. Headquartered in California, it has been a subsidiary of Microsoft since 2018. It is commonly used to host open source software development projects. As of June 2022, GitHub reported having over 83 million developers and more than 200 million repositories, including at least 28 million public repositories. It is the largest source code host . History GitHub.com Development of the GitHub.com platform began on October 19, 2007. The site was launched in April 2008 by Tom Preston-Werner, Chris Wanstrath, P. J. Hyett and Scott Chacon after it had been made available for a few months prior as a beta release. GitHub has an annual keynote called GitHub Universe. Organizat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Open-source Software
Open-source software (OSS) is computer software that is released under a license in which the copyright holder grants users the rights to use, study, change, and distribute the software and its source code to anyone and for any purpose. Open-source software may be developed in a collaborative public manner. Open-source software is a prominent example of open collaboration, meaning any capable user is able to participate online in development, making the number of possible contributors indefinite. The ability to examine the code facilitates public trust in the software. Open-source software development can bring in diverse perspectives beyond those of a single company. A 2008 report by the Standish Group stated that adoption of open-source software models has resulted in savings of about $60 billion per year for consumers. Open source code can be used for studying and allows capable end users to adapt software to their personal needs in a similar way user scripts a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
FAIR Data
FAIR data are data which meet principles of findability, accessibility, interoperability, and reusability (FAIR). The acronym and principles were defined in a March 2016 paper in the journal '' Scientific Data'' by a consortium of scientists and organizations. The FAIR principles emphasize machine-actionability (i.e., the capacity of computational systems to find, access, interoperate, and reuse data with none or minimal human intervention) because humans increasingly rely on computational support to deal with data as a result of the increase in volume, complexity, and creation speed of data. Material was copied from this source, which is available under Creative Commons Attribution 4.0 International License The abbreviation is sometimes used to indicate that the dataset or database in question complies with the FAIR principles and also carries an explicit data‑capable open license. FAIR principles, as published by GO FAIR Acceptance and implementation of FAIR data ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Knowledge Graph
The Google Knowledge Graph is a knowledge base from which Google serves relevant information in an infobox beside its search results. This allows the user to see the answer in a glance. The data is generated automatically from a variety of sources, covering places, people, businesses, and more. The information covered by Google's Knowledge Graph grew quickly after launch, tripling its size within seven months (covering 570 million entities and 18 billion facts). By mid-2016, Google reported that it held 70 billion facts and answered "roughly one-third" of the 100 billion monthly searches they handled. By May 2020, this had grown to 500 billion facts on 5 billion entities. There is no official documentation of how the Google Knowledge Graph is implemented. According to Google, its information is retrieved from many sources, including the ''CIA World Factbook'' and Wikipedia. It is used to answer direct spoken questions in Google Assistant and Google Home voice queries. It h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Semantic Web (journal)
''Semantic Web - Interoperability, Usability, Applicability'' is a bimonthly peer-reviewed scientific journal published by IOS Press. It was established in 2010 and covers the foundations and applications of semantic web technologies and linked data. The journal uses an open peer-review process. The journal publishes its metadata online in the form of Linked Data and provides scientometrics such as the geographic distribution of authors, citation networks, trends in research topics over time, and so forth. The editors-in-chief are Pascal Hitzler (Kansas State University) and Krzysztof Janowicz (University of California, Santa Barbara). The journal originally combined freely available author-versions of accepted papers with a subscription model and optional open access to published versions (green open access together with hybrid open access). In October 2019 the journal announced that it will go full (gold) open access and full open access was implemented 1 January 2020. Startin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ScienceDaily
''Science Daily'' is an American website launched in 1995 that aggregates press releases and publishes lightly edited press releases (a practice called churnalism) about science, similar to Phys.org and EurekAlert!. The site was founded by married couple Dan and Michele Hogan in 1995; Dan Hogan formerly worked in the public affairs department of Jackson Laboratory The Jackson Laboratory (often abbreviated as JAX) is an independent, non-profit biomedical research institution which was founded by a eugenicist. It employs more than 3,000 employees in Bar Harbor, Maine; Sacramento, California; Farmington, ... writing press releases. The site makes money from selling advertisements. As of 2010, the site said that it had grown "from a two-person operation to a full-fledged news business with worldwide contributors". At the time, it was run out of the Hogans' home, had no reporters, and only reprinted press releases. In 2012, Quantcast ranked it at 614 with 2.6 million U.S ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Algebraic Topology
Algebraic topology is a branch of mathematics that uses tools from abstract algebra to study topological spaces. The basic goal is to find algebraic invariants that classify topological spaces up to homeomorphism, though usually most classify up to homotopy equivalence. Although algebraic topology primarily uses algebra to study topological problems, using topology to solve algebraic problems is sometimes also possible. Algebraic topology, for example, allows for a convenient proof that any subgroup of a free group is again a free group. Main branches of algebraic topology Below are some of the main areas studied in algebraic topology: Homotopy groups In mathematics, homotopy groups are used in algebraic topology to classify topological spaces. The first and simplest homotopy group is the fundamental group, which records information about loops in a space. Intuitively, homotopy groups record information about the basic shape, or holes, of a topological space. Homology ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neural Clique
Neural cliques are network-level memory coding units in the hippocampus. They are functionally organized in a categorical and hierarchical manner. Researchers investigating the role of neural cliques have gained insight into the process of storing memories in the brain. Research evidence suggests that memory of events is achieved not through memorization of exact event details but through recreation of select images based on cognitive significance. This process enables the brain to exhibit large storage capacity and facilitates the capacity for abstract reasoning and generalization. Although several studies converges in the demonstration that real-time patterns of memory traces and sensory inputs are retained in the form of neural cliques, the topic is currently in active research in order to fully understand this biological code. History Hebb proposed in 1949 that information in the brain would need to involve the coordinated activity of multiple neuronal cells, termed engrams o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
