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Biomedical Primate Research Centre
The Biomedical Primate Research Centre (BPRC) is Europe's largest primate animal testing research centre. It is a scientific research institute that performs research that contributes to the identification and development of new medicines against deadly diseases. It is located in Rijswijk (South Holland) and employs about 110 people. The BPRC is funded by the Dutch Ministry of Education, Culture and Science. Before it became an independent foundation on December 7, 1994, it was part of the Netherlands Organisation for Applied Scientific Research. The main research areas are Immunobiology, Parasitology, Virology, Ethology and Alternatives for Animal Research. The BPRC houses rhesus macaques and marmosets to be used in biomedical research involving AIDS, malaria, hepatitis, tuberculosis and auto-immune diseases. In 2002 the Dutch government forbade any further testing on chimpanzees, though it allowed trials already in progress to end. In 2015, BPRC was reported to use about 20 ...
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Animal Testing On Non-human Primates
Experiments involving non-human primates (NHPs) include toxicity testing for medical and non-medical substances; studies of infectious disease, such as HIV and hepatitis; neurological studies; behavior and cognition; reproduction; genetics; and xenotransplantation. Around 65,000 NHPs are used every year in the United States, and around 7,000 across the European Union. Most are purpose-bred, while some are caught in the wild."Animals used in research"
, U.S. Department of Agriculture, p. 10
Their use is controversial. According to the , NHPs are used because their brains share structural and functional features wi ...
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Common Chimpanzee
The chimpanzee (''Pan troglodytes''), also known as simply the chimp, is a species of Hominidae, great ape native to the forest and savannah of tropical Africa. It has four confirmed subspecies and a fifth proposed subspecies. When its close relative the bonobo was more commonly known as the pygmy chimpanzee, this species was often called the common chimpanzee or the robust chimpanzee. The chimpanzee and the bonobo are the only species in the genus Pan (genus), ''Pan''. Evidence from fossils and DNA sequencing shows that ''Pan'' is a sister taxon to the Human evolution, human lineage and is humans' closest living relative. The chimpanzee is covered in coarse black hair, but has a bare face, fingers, toes, palms of the hands, and soles of the feet. It is larger and more Robustness (morphology), robust than the bonobo, weighing for males and for females and standing . The chimpanzee lives in groups that range in size from 15 to 150 members, although individuals travel and forag ...
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Primate Research Centers
Primates are a diverse order of mammals. They are divided into the strepsirrhines, which include the lemurs, galagos, and lorisids, and the haplorhines, which include the tarsiers and the simians (monkeys and apes, the latter including humans). Primates arose 85–55 million years ago first from small terrestrial mammals, which adapted to living in the trees of tropical forests: many primate characteristics represent adaptations to life in this challenging environment, including large brains, visual acuity, color vision, a shoulder girdle allowing a large degree of movement in the shoulder joint, and dextrous hands. Primates range in size from Madame Berthe's mouse lemur, which weighs , to the eastern gorilla, weighing over . There are 376–524 species of living primates, depending on which classification is used. New primate species continue to be discovered: over 25 species were described in the 2000s, 36 in the 2010s, and three in the 2020s. Primates have large brain ...
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Organizations Established In 1994
An organization or organisation (Commonwealth English; see spelling differences), is an entity—such as a company, an institution, or an association—comprising one or more people and having a particular purpose. The word is derived from the Greek word ''organon'', which means tool or instrument, musical instrument, and organ. Types There are a variety of legal types of organizations, including corporations, governments, non-governmental organizations, political organizations, international organizations, armed forces, charities, not-for-profit corporations, partnerships, cooperatives, and educational institutions, etc. A hybrid organization is a body that operates in both the public sector and the private sector simultaneously, fulfilling public duties and developing commercial market activities. A voluntary association is an organization consisting of volunteers. Such organizations may be able to operate without legal formalities, depending on jurisdiction, includ ...
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Animal Testing
Animal testing, also known as animal experimentation, animal research, and ''in vivo'' testing, is the use of non-human animals in experiments that seek to control the variables that affect the behavior or biological system under study. This approach can be contrasted with field studies in which animals are observed in their natural environments or habitats. Experimental research with animals is usually conducted in universities, medical schools, pharmaceutical companies, defense establishments, and commercial facilities that provide animal-testing services to the industry. The focus of animal testing varies on a continuum from pure research, focusing on developing fundamental knowledge of an organism, to applied research, which may focus on answering some questions of great practical importance, such as finding a cure for a disease. Examples of applied research include testing disease treatments, breeding, defense research, and toxicology, including cosmetics testing. In edu ...
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Animal Rights
Animal rights is the philosophy according to which many or all sentient animals have moral worth that is independent of their utility for humans, and that their most basic interests—such as avoiding suffering—should be afforded the same consideration as similar interests of human beings. Broadly speaking, and particularly in popular discourse, the term "animal rights" is often used synonymously with "animal protection" or "animal liberation". More narrowly, "animal rights" refers to the idea that many animals have fundamental rights to be treated with respect as individuals—rights to life, liberty, and freedom from torture that may not be overridden by considerations of aggregate welfare. Many advocates for animal rights oppose the assignment of moral value and fundamental protections on the basis of species membership alone. This idea, known as speciesism, is considered by them to be a prejudice as irrational as any other. They maintain that animals should no long ...
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Vice News
Vice News (stylized as VICE News) is Vice Media's current affairs channel, producing daily documentary essays and video through its website and YouTube channel. It promotes itself on its coverage of "under-reported stories". Vice News was created in December 2013 and is based in New York City, though it has bureaus worldwide. History Before Vice News was founded, ''Vice'' published news documentaries and news reports from around the world through its YouTube channel alongside other programs. ''Vice'' had reported on events such as crime in Venezuela, the Israeli–Palestinian conflict, protests in Turkey, the North Korean and Iranian regimes, the Uyghur genocide, and the Syrian Civil War through their own YouTube channel and website. After the creation of Vice News as a separate division, its reporting greatly increased with worldwide coverage starting immediately with videos published on YouTube and articles on its website daily. In December 2013, Vice Media expanded its in ...
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Monkey
Monkey is a common name that may refer to most mammals of the infraorder Simiiformes, also known as the simians. Traditionally, all animals in the group now known as simians are counted as monkeys except the apes, which constitutes an incomplete paraphyletic grouping; however, in the broader sense based on cladistics, apes (Hominoidea) are also included, making the terms ''monkeys'' and ''simians'' synonyms in regards to their scope. In 1812, Geoffroy grouped the apes and the Cercopithecidae group of monkeys together and established the name Catarrhini, "Old World monkeys", ("''singes de l'Ancien Monde''" in French). The extant sister of the Catarrhini in the monkey ("singes") group is the Platyrrhini (New World monkeys). Some nine million years before the divergence between the Cercopithecidae and the apes, the Platyrrhini emerged within "monkeys" by migration to South America likely by ocean. Apes are thus deep in the tree of extant and extinct monkeys, and any of the ...
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Auto-immune
In immunology, autoimmunity is the system of immune responses of an organism against its own healthy cells, tissues and other normal body constituents. Any disease resulting from this type of immune response is termed an "autoimmune disease". Prominent examples include celiac disease, post-infectious IBS, diabetes mellitus type 1, Henoch–Schönlein purpura (HSP) sarcoidosis, systemic lupus erythematosus (SLE), Sjögren syndrome, eosinophilic granulomatosis with polyangiitis, Hashimoto's thyroiditis, Graves' disease, idiopathic thrombocytopenic purpura, Addison's disease, rheumatoid arthritis (RA), ankylosing spondylitis, polymyositis (PM), dermatomyositis (DM), Alopecia Areata and multiple sclerosis (MS). Autoimmune diseases are very often treated with steroids. Autoimmunity means presence of antibodies or T cells that react with self-protein and is present in all individuals, even in normal health state. It causes autoimmune diseases if self-reactivity can lead to tissue d ...
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Rijswijk
Rijswijk (), formerly known as Ryswick ( ) in English, is a city and municipality in the western Netherlands, in the province of South Holland. Its population was in , and it has an area of , of which is water. The municipality also includes the former villages 't Haantje and Sion, currently also known as Rijswijk-Buiten. Demographics 62% Dutch background, 38% No Dutch background History Archeological excavations indicate that this area of the coastal dunes was already inhabited some 5500 years ago. The formation of the village Rijswijk took place in the 13th century, and its history was dominated by presence of mansions and estates of the nobility and affluent. Among the many country estates known to have been in Rijswijk are: * Arentsburg * Burchvliet * Cromvliet * Den Burgh * De Voorde * Drievliet * 's-Gravenmade * Haag- en Delftzicht * Hilvoorde * Hoekenburg * Hofrust * Hoornwijk * Huis te Werve * Huis ter Nieuwburg * Leeuwendaal * Oversteen * Overvoorde * Schoonoord ...
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Tuberculosis
Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in which case it is known as latent tuberculosis. Around 10% of latent infections progress to active disease which, if left untreated, kill about half of those affected. Typical symptoms of active TB are chronic cough with blood-containing mucus, fever, night sweats, and weight loss. It was historically referred to as consumption due to the weight loss associated with the disease. Infection of other organs can cause a wide range of symptoms. Tuberculosis is spread from one person to the next through the air when people who have active TB in their lungs cough, spit, speak, or sneeze. People with Latent TB do not spread the disease. Active infection occurs more often in people with HIV/AIDS and in those who smoke. Diagnosis of active TB is ...
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Hepatitis
Hepatitis is inflammation of the liver tissue. Some people or animals with hepatitis have no symptoms, whereas others develop yellow discoloration of the skin and whites of the eyes (jaundice), poor appetite, vomiting, tiredness, abdominal pain, and diarrhea. Hepatitis is ''acute'' if it resolves within six months, and '' chronic'' if it lasts longer than six months. Acute hepatitis can resolve on its own, progress to chronic hepatitis, or (rarely) result in acute liver failure. Chronic hepatitis may progress to scarring of the liver (cirrhosis), liver failure, and liver cancer. Hepatitis is most commonly caused by the virus ''hepatovirus A'', '' B'', '' C'', '' D'', and '' E''. Other viruses can also cause liver inflammation, including cytomegalovirus, Epstein–Barr virus, and yellow fever virus. Other common causes of hepatitis include heavy alcohol use, certain medications, toxins, other infections, autoimmune diseases, and non-alcoholic steatohepatitis (NASH). Hepa ...
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