Bioinformatics Institute (Singapore)
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Bioinformatics Institute (Singapore)
The Bioinformatics Institute (Abbreviation: BII) is one of the Biomedical Sciences Institutes of the ''Agency for Science, Technology and Research, (A*STAR).'' BII was originally founded in 2001 by Dr Rajagopal as a support unit for Bioinformatics and IT service management. However, since August 2007, it has been redefined as a biological research organisation upon the arrival of the current executive director, Dr Frank Eisenhaber. BII focuses on "computationally biology-driven life science research aimed at the discovery of biomolecular mechanisms." BII also develops computer based research tools and performs experimental verifications in its own experimental facilities or by collaborating with appropriate groups. BII is home to the journal Scientific Phone Apps and Mobile Devices with SpringerNature. There are currently four research divisions in BII: *Biomolecular Sequence to Function *Biomolecular Modelling and Design *Imaging Informatics *Translational Research Under Dr. S ...
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Agency For Science, Technology And Research
The Agency for Science, Technology and Research (A*STAR) is a statutory board under the Ministry of Trade and Industry of Singapore. The agency supports R&D that is aligned to areas of competitive advantage and national needs for Singapore. These span the four technology domains of Manufacturing, Trade and Connectivity, Human Health and Potential, Urban Solutions and Sustainability, and Smart Nation and Digital Economy set out under the nation's five-year R&D plan (RIE2025). The agency's research institutes are located mostly in Biopolis and Fusionopolis. The total strength of the A*STAR community, including scientists and researchers, technical and non-technical staff, and industry development and commercialization staff is approximately at 5,400. History A*STAR was established on 11 January 1991. It was formerly known as the National Science and Technology Board (NSTB) until January 2002. On 29 October 2003, Singapore's hub for the biomedical sciences, Biopolis, was ...
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Bioinformatics
Bioinformatics () is an interdisciplinary field that develops methods and software tools for understanding biological data, in particular when the data sets are large and complex. As an interdisciplinary field of science, bioinformatics combines biology, chemistry, physics, computer science, information engineering, mathematics and statistics to analyze and interpret the biological data. Bioinformatics has been used for '' in silico'' analyses of biological queries using computational and statistical techniques. Bioinformatics includes biological studies that use computer programming as part of their methodology, as well as specific analysis "pipelines" that are repeatedly used, particularly in the field of genomics. Common uses of bioinformatics include the identification of candidates genes and single nucleotide polymorphisms (SNPs). Often, such identification is made with the aim to better understand the genetic basis of disease, unique adaptations, desirable properties (e ...
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IT Service Management
Information technology service management (ITSM) is the activities that are performed by an organization to design, build, deliver, operate and control information technology (IT) services offered to customers. Differing from more technology-oriented IT management approaches like network management and IT systems management, IT service management is characterized by adopting a process approach towards management, focusing on customer needs and IT services for customers rather than IT systems, and stressing continual improvement. The CIO WaterCoolers' annual ITSM report states that business uses ITSM "mostly in support of customer experience (35%) and service quality (48%)." Context As a discipline, ITSM has ties and common interests with other IT and general management approaches, information security management and software engineering. Consequently, IT service management frameworks have been influenced by other standards and adopted concepts from them, e.g. CMMI, ISO 9000 ...
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Springer Nature
Springer Nature or the Springer Nature Group is a German-British academic publishing company created by the May 2015 merger of Springer Science+Business Media and Holtzbrinck Publishing Group's Nature Publishing Group, Palgrave Macmillan, and Macmillan Education. History The company originates from a number of journals and publishing houses, notably Springer-Verlag, which was founded in 1842 by Julius Springer in Berlin (the grandfather of Bernhard Springer who founded Springer Publishing in 1950 in New York), Nature Publishing Group which has published ''Nature (journal) , Nature'' since 1869, and Macmillan Education, which goes back to Macmillan Publishers founded in 1843. Springer Nature was formed in 2015 by the merger of Nature Publishing Group, Palgrave Macmillan and Macmillan Education (held by Holtzbrinck Publishing Group) with Springer Science+Business Media (held by BC Partners). Plans for the merger were first announced on 15 January 2015. The transaction was concluded ...
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GISAID
GISAID (Global Initiative on Sharing Avian Influenza Data) is a global science initiative and primary source established in 2008 that provides open access to genomic data of influenza viruses and the coronavirus responsible for the COVID-19 pandemic. On January 10, 2020, the first whole-genome sequences of SARS-CoV-2 were made available on GISAID, which enabled global responses to the pandemic, including the development of the first vaccines and diagnostic tests to detect SARS-CoV-2. The database has become the world's largest repository for SARS-CoV-2 sequences. GISAID facilitates genomic epidemiology and real-time surveillance to monitor the emergence of new COVID-19 viral strains across the planet. Since its establishment as an alternative to sharing avian influenza data via conventional public-domain archives, GISAID has been recognized for incentivizing rapid exchange of outbreak data during the H1N1 pandemic in 2009, the H7N9 epidemic in 2013, and the COVID-19 pandemic in e ...
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COVID-19
Coronavirus disease 2019 (COVID-19) is a contagious disease caused by a virus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first known case was COVID-19 pandemic in Hubei, identified in Wuhan, China, in December 2019. The disease quickly spread worldwide, resulting in the COVID-19 pandemic. The symptoms of COVID‑19 are variable but often include fever, cough, headache, fatigue, breathing difficulties, Anosmia, loss of smell, and Ageusia, loss of taste. Symptoms may begin one to fourteen days incubation period, after exposure to the virus. At least a third of people who are infected Asymptomatic, do not develop noticeable symptoms. Of those who develop symptoms noticeable enough to be classified as patients, most (81%) develop mild to moderate symptoms (up to mild pneumonia), while 14% develop severe symptoms (dyspnea, Hypoxia (medical), hypoxia, or more than 50% lung involvement on imaging), and 5% develop critical symptoms (respiratory failure ...
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Genetics Or Genomics Research Institutions
Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinians, Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today, is a somewhat ambiguous definition of what is referred to as a gene. Phenotypic trait, Trait inheritance and Molecular genetics, molecular inheritance mechanisms of genes are still primary principles of genetics in the 21st century, but modern genetics has expanded to study the function and behavior of genes. Gene structure and function, variation, and distribution are studied within the context of the Cell (biolo ...
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