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Beano (dietary Supplement)
Beano is an enzyme-based dietary supplement that is used to reduce gas in the digestive tract, thereby improving digestion and reducing bloating, discomfort, and flatulence caused by gas. It contains the enzyme alpha-galactosidase (α-GAL). It was introduced as a liquid, but that has been discontinued and it is now available only as tablets and strawberry-flavored "Meltaways". Beano is marketed and distributed by Prestige Brands Holdings, Inc. Mechanism of action Beano contains the enzyme α-GAL, which is derived from the fungus ''Aspergillus niger''. The enzyme works in the digestive tract to break down the complex or branching sugars (polysaccharides and oligosaccharides) in foods such as legumes (beans and peanuts) and cruciferous vegetables (cauliflower, broccoli, cabbage, and brussels sprouts, among others). The enzyme breaks those complex sugars into simple sugars, making these foods somewhat more digestible, and reducing intestinal gas. The polysaccharides and oligosac ...
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Beano OTC
Beano may refer to: Arts and entertainment * Beano, another name for the American version of Bingo, a game of chance * Beano, a character on the American television sitcom ''Out of This World'' * ''The Beano'', a British children's comic featuring mainly humour * ''The Beano Album'', colloquial name for '' Blues Breakers with Eric Clapton'', a 1966 album by John Mayall and the Bluesbreakers People * Beano Cook (1931–2012), ESPN sports commentator * Brian McDonald (Gaelic footballer) (born 1980), Gaelic footballer nicknamed "Beano" Other uses * Beano (dietary supplement), used to prevent flatulence * Beanos, a former second-hand record shop, once the largest in Europe, located in Croydon, England * T13 Beano Grenade, an experimental hand grenade * Beano, short for bean-feast A bean-feast, also known as beano in Britain, is an informal term for a celebratory meal or party, especially an annual summer dinner given by an employer to their employees. Its probable origin is th ...
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Brussels Sprouts
The Brussels sprout is a member of the Gemmifera cultivar group of cabbages (''Brassica oleracea''), grown for its edible buds. The leaf vegetables are typically 1.5–4.0 cm (0.6–1.6 in) in diameter and resemble miniature cabbages. The Brussels sprout has long been popular in Brussels, Belgium, from which it gained its name. Etymology Although native to the Mediterranean region with other cabbage species, Brussels sprouts first appeared in northern Europe during the 5th century, later being cultivated in the 13th century near Brussels, Belgium, from which they derived their name. Its Group (horticulture), group name Gemmifera (or lowercase and italicized ''gemmifera'' as a variety (botany), variety name) means ' (bud-producing). Cultivation Forerunners to modern Brussels sprouts were probably cultivated in Ancient Rome. Brussels sprouts as they are now known were grown possibly as early as the 13th century in what is now Belgium. The first written reference dates ...
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Block Drug
Block Drug Company was a pharmaceutical company based in Minneapolis, Minnesota, United States, that specialized in dental care products. Its most popular products included Polident denture cleanser, Poli-Grip denture adhesive, Dentu-Creme denture toothpaste, Nytol sleeping pill, Tegrin medicated shampoo for psoriasis, Lava hand soaps (acquired from Procter & Gamble), Beano and Phazyme anti-gas products, Balmex diaper rash ointments, and Sensodyne desensitizing toothpaste.The Gale Group. ''International Directory of Company Histories'', republished a"Block Drug Company, Inc.: Information from Answers.com" Answers Corporation. GlaxoSmithKline purchased the company for $1.24 billion in 2001.GlaxoSmithKline Compl ...
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GlaxoSmithKline
GSK plc, formerly GlaxoSmithKline plc, is a British multinational pharmaceutical and biotechnology company with global headquarters in London, England. Established in 2000 by a merger of Glaxo Wellcome and SmithKline Beecham. GSK is the tenth largest pharmaceutical company and #294 on the 2022 ''Fortune'' Global 500, ranked behind other pharmaceutical companies China Resources, Sinopharm, Johnson & Johnson, Pfizer, Roche, AbbVie, Novartis, Bayer, and Merck. The company has a primary listing on the London Stock Exchange and is a constituent of the FTSE 100 Index. , it had a market capitalisation of £70 billion, the eighth largest on the London Stock Exchange. It has a secondary listing on the New York Stock Exchange. The company developed the first malaria vaccine, RTS,S, which it said in 2014 it would make available for five percent above cost. Legacy products developed at GSK include several listed in the World Health Organization's List of Essential Medicines, such ...
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Ig Nobel Prize
The Ig Nobel Prize ( ) is a satiric prize awarded annually since 1991 to celebrate ten unusual or trivial achievements in scientific research. Its aim is to "honor achievements that first make people laugh, and then make them think." The name of the award is a pun on the Nobel Prize, which it parodies, and on the word '' ignoble'' ("not noble"). Organized by the scientific humor magazine, '' Annals of Improbable Research'' (AIR), the Ig Nobel Prizes are presented by Nobel laureates in a ceremony at the Sanders Theater, Harvard University, and are followed by the winners' public lectures at the Massachusetts Institute of Technology. History The Ig Nobels were created in 1991 by Marc Abrahams, editor and co-founder of the '' Annals of Improbable Research'', a former editor-in-chief of the ''Journal of Irreproducible Results'' who has been master of ceremonies at all awards ceremonies. Awards were presented at that time for discoveries "that cannot, or should not, be reproduced ...
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Fart Proudly
"Fart Proudly" (also called "A Letter to a Royal Academy about farting", and "To the Royal Academy of Farting") is the popular name of an essay about flatulence written by Benjamin Franklin  1781 while he was living abroad as United States Ambassador to France. It is an example of flatulence humor. Description "A Letter to a Royal Academy" was composed in response to a call for scientific papers from the Royal Academy of Brussels. Franklin believed that the various academic societies in Europe were increasingly pretentious and concerned with the impractical. Revealing his "bawdy, scurrilous side," Franklin responded with an essay suggesting that research and practical reasoning be undertaken into methods of improving the odor of human flatulence. The essay was never submitted but was sent as a letter to Richard Price, a Welsh philosopher and Unitarian minister in England with whom Franklin had an ongoing correspondence. The text of the essay's introduction reads in par ...
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Benjamin Franklin
Benjamin Franklin ( April 17, 1790) was an American polymath who was active as a writer, scientist, inventor, statesman, diplomat, printer, publisher, and political philosopher. Encyclopædia Britannica, Wood, 2021 Among the leading intellectuals of his time, Franklin was one of the Founding Fathers of the United States, a drafter and signer of the United States Declaration of Independence, and the first United States Postmaster General. As a scientist, he was a major figure in the American Enlightenment and the history of physics for his studies of electricity, and for charting and naming the current still known as the Gulf Stream. As an inventor, he is known for the lightning rod, bifocals, and the Franklin stove, among others. He founded many civic organizations, including the Library Company, Philadelphia's first fire department, and the University of Pennsylvania. Isaacson, 2004, p. Franklin earned the title of "The First American" for his early and indefa ...
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Acarbose
Acarbose (INN) is an anti-diabetic drug used to treat diabetes mellitus type 2 and, in some countries, prediabetes. It is a generic sold in Europe and China as Glucobay (Bayer AG), in North America as Precose (Bayer Pharmaceuticals), and in Canada as Prandase (Bayer AG). It is cheap and popular in China, but not in the U.S. One physician explains the use in the U.S. is limited because it is not potent enough to justify the side effects of diarrhea and flatulence. However, a recent large study concludes "acarbose is effective, safe and well tolerated in a large cohort of Asian patients with type 2 diabetes." A possible explanation for the differing opinions is an observation that acarbose is significantly more effective in patients eating a relatively high carbohydrate Eastern diet. It is a starch blocker, and inhibits alpha glucosidase, an intestinal enzyme that releases glucose from larger carbohydrates. It is composed of an acarviosin moiety with a maltose at the reducing ter ...
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Randomized Controlled Trials
A randomized controlled trial (or randomized control trial; RCT) is a form of scientific experiment used to control factors not under direct experimental control. Examples of RCTs are clinical trials that compare the effects of drugs, surgical techniques, medical devices, diagnostic procedures or other medical treatments. Participants who enroll in RCTs differ from one another in known and unknown ways that can influence study outcomes, and yet cannot be directly controlled. By randomly allocating participants among compared treatments, an RCT enables ''statistical control'' over these influences. Provided it is designed well, conducted properly, and enrolls enough participants, an RCT may achieve sufficient control over these confounding factors to deliver a useful comparison of the treatments studied. Definition and examples An RCT in clinical research typically compares a proposed new treatment against an existing standard of care; these are then termed the 'experimental' a ...
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Fermentation (biochemistry)
Fermentation is a metabolic process that produces chemical changes in organic substrates through the action of enzymes. In biochemistry, it is narrowly defined as the extraction of energy from carbohydrates in the absence of oxygen. In food production, it may more broadly refer to any process in which the activity of microorganisms brings about a desirable change to a foodstuff or beverage. The science of fermentation is known as zymology. In microorganisms, fermentation is the primary means of producing adenosine triphosphate (ATP) by the degradation of organic nutrients anaerobically. Humans have used fermentation to produce foodstuffs and beverages since the Neolithic age. For example, fermentation is used for preservation in a process that produces lactic acid found in such sour foods as pickled cucumbers, kombucha, kimchi, and yogurt, as well as for producing alcoholic beverages such as wine and beer. Fermentation also occurs within the gastrointestinal tracts of all an ...
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Intestinal Flora
Gut microbiota, gut microbiome, or gut flora, are the microorganisms, including bacteria, archaea, fungi, and viruses that live in the digestive tracts of animals. The gastrointestinal metagenome is the aggregate of all the genomes of the gut microbiota. The gut is the main location of the human microbiome. The gut microbiota has broad impacts, including effects on colonization, resistance to pathogens, maintaining the intestinal epithelium, metabolizing dietary and pharmaceutical compounds, controlling immune function, and even behavior through the gut–brain axis. The microbial composition of the gut microbiota varies across regions of the digestive tract. The colon contains the highest microbial density recorded in any habitat on Earth, representing between 300 and 1000 different species. Bacteria are the largest and to date, best studied component and 99% of gut bacteria come from about 30 or 40 species. Up to 60% of the dry mass of feces is bacteria. Over 99% of the bact ...
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Large Intestine
The large intestine, also known as the large bowel, is the last part of the gastrointestinal tract and of the digestive system in tetrapods. Water is absorbed here and the remaining waste material is stored in the rectum as feces before being removed by defecation. The colon is the longest portion of the large intestine, and the terms are often used interchangeably but most sources define the large intestine as the combination of the cecum, colon, rectum, and anal canal. Some other sources exclude the anal canal. In humans, the large intestine begins in the right iliac region of the pelvis, just at or below the waist, where it is joined to the end of the small intestine at the cecum, via the ileocecal valve. It then continues as the colon ascending the abdomen, across the width of the abdominal cavity as the transverse colon, and then descending to the rectum and its endpoint at the anal canal. Overall, in humans, the large intestine is about long, which is about one-fi ...
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