Australian Phytochemical Survey
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Australian Phytochemical Survey
The Australian Phytochemical Survey was a collaborative study of the chemical constituents of native plants in Australia and Papua New Guinea which was conducted by CSIRO as well as chemists within the Australian university system. The project was primarily based around a broad search across a range of Australian ecosystems and plant species for new medicinal drugs as well as additional studies on plants which were poisonous to livestock. The survey was active from 1946 until 1974 with pharmacological testing of alkaloids initially being carried out by F.H. Shaw at the University of Melbourne. The Australian Phytochemical Survey later also fostered collaborations with Smith, Kline & French, a pharmaceutical company from Philadelphia as well as National Institutes of Health Clinical Center in Bethesda, Maryland which was established in relation to the screening and study of potential anti-tumour agents arising through the survey. The survey was initiated as a search for chemical cons ...
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CSIRO
The Commonwealth Scientific and Industrial Research Organisation (CSIRO) is an Australian Government The Australian Government, also known as the Commonwealth Government, is the national government of Australia, a federal parliamentary constitutional monarchy. Like other Westminster-style systems of government, the Australian Government ... agency responsible for scientific research. CSIRO works with leading organisations around the world. From its headquarters in Canberra, CSIRO maintains more than 50 sites across Australia and in France, Chile and the United States, employing about 5,500 people. Federally funded scientific research began in Australia years ago. The Advisory Council of Science and Industry was established in 1916 but was hampered by insufficient available finance. In 1926 the research effort was reinvigorated by establishment of the Council for Scientific and Industrial Research (CSIR), which strengthened national science leadership and increased ...
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Alkaloids
Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds with neutral and even weakly acidic properties. Some synthetic compounds of similar structure may also be termed alkaloids. In addition to carbon, hydrogen and nitrogen, alkaloids may also contain oxygen, sulfur and, more rarely, other elements such as chlorine, bromine, and phosphorus.Chemical Encyclopedia: alkaloids
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Alkaloids are produced by a large variety of organisms including , ,

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University Of Melbourne
The University of Melbourne is a public research university located in Melbourne, Australia. Founded in 1853, it is Australia's second oldest university and the oldest in Victoria. Its main campus is located in Parkville, an inner suburb north of Melbourne's central business district, with several other campuses located across Victoria. Incorporated in the 19th century by the colony of Victoria, the University of Melbourne is one of Australia's six sandstone universities and a member of the Group of Eight, Universitas 21, Washington University's McDonnell International Scholars Academy, and the Association of Pacific Rim Universities. Since 1872, many residential colleges have become affiliated with the university, providing accommodation for students and faculty, and academic, sporting and cultural programs. There are ten colleges located on the main campus and in nearby suburbs. The university comprises ten separate academic units and is associated with numerous institut ...
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Smith, Kline & French
Smith, Kline & French (SKF) was an American pharmaceutical company. History In 1830, John K. Smith opened a drugstore in Philadelphia, and his younger brother, George, joined him in 1841 to form John K Smith & Co. In 1865, Mahlon Kline joined ''Smith and Shoemaker'', as John K Smith and Co had become in the meantime, as a bookkeeper. In 1875, he took on additional responsibilities as a salesman and added many new and large accounts, as a reward the company, Mahlon K Smith and Company, was renamed into Smith, Kline and Company. In 1891, Smith, Kline and Company acquired French, Richards and Company, founded in 1844 by Clayton French and William Richards, which provided the company with a greater portfolio of consumer brands. In 1929 ''Smith, Kline and French Company'' was renamed into ''Smith Kline and French Laboratories'' and the company put more focus on research in order to sustain its business. In 1932, SKF chemist Gordon Alles was awarded a patent for amphetamine. In 19 ...
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Philadelphia
Philadelphia, often called Philly, is the largest city in the Commonwealth of Pennsylvania, the sixth-largest city in the U.S., the second-largest city in both the Northeast megalopolis and Mid-Atlantic regions after New York City. Since 1854, the city has been coextensive with Philadelphia County, the most populous county in Pennsylvania and the urban core of the Delaware Valley, the nation's seventh-largest and one of world's largest metropolitan regions, with 6.245 million residents . The city's population at the 2020 census was 1,603,797, and over 56 million people live within of Philadelphia. Philadelphia was founded in 1682 by William Penn, an English Quaker. The city served as capital of the Pennsylvania Colony during the British colonial era and went on to play a historic and vital role as the central meeting place for the nation's founding fathers whose plans and actions in Philadelphia ultimately inspired the American Revolution and the nation's inde ...
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National Institutes Of Health Clinical Center
The NIH Clinical Center is a hospital solely dedicated to clinical research at the National Institutes of Health campus in Bethesda, Maryland. The Clinical Center, known as Building 10, consists of the original part of the hospital, the Warren Grant Magnuson Clinical Center, and the newest addition, the Mark O. Hatfield Clinical Research Center. The two parts are connected to form one large building. Since the hospital's opening in 1953, NIH scientists have worked with volunteer patients to create medical innovations. Clinical Center successes include pioneering the cure of cancerous solid tumors with chemotherapy; the use of nitroglycerin to treat heart attacks; identifying a genetic component in schizophrenia; conducting the first successful replacement of a mitral valve to treat heart disease; and the creation of blood tests to identify both Acquired Immune Deficiency Syndrome (AIDS) and hepatitis. In October 2014, Clinical Center staff successfully treated one of the first fe ...
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Bethesda, Maryland
Bethesda () is an unincorporated, census-designated place in southern Montgomery County, Maryland. It is located just northwest of Washington, D.C. It takes its name from a local church, the Bethesda Meeting House (1820, rebuilt 1849), which in turn took its name from Jerusalem's Pool of Bethesda. The National Institutes of Health's main campus and the Walter Reed National Military Medical Center are in Bethesda, in addition to a number of corporate and government headquarters. As an unincorporated community, Bethesda has no official boundaries. According to the 2020 U.S. census, the community had a total population of 68,056. History Bethesda is located in a region that was populated by the Piscataway and Nacotchtank tribes at the time of European colonization. Fur trader Henry Fleet became the first European to visit the area, reaching it by sailing up the Potomac River. He stayed with the Piscataway tribe from 1623 to 1627, either as a guest or prisoner (historical accounts ...
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Organic Chemistry
Organic chemistry is a subdiscipline within chemistry involving the scientific study of the structure, properties, and reactions of organic compounds and organic materials, i.e., matter in its various forms that contain carbon atoms.Clayden, J.; Greeves, N. and Warren, S. (2012) ''Organic Chemistry''. Oxford University Press. pp. 1–15. . Study of structure determines their structural formula. Study of properties includes physical and chemical properties, and evaluation of chemical reactivity to understand their behavior. The study of organic reactions includes the chemical synthesis of natural products, drugs, and polymers, and study of individual organic molecules in the laboratory and via theoretical ( in silico) study. The range of chemicals studied in organic chemistry includes hydrocarbons (compounds containing only carbon and hydrogen) as well as compounds based on carbon, but also containing other elements, especially oxygen, nitrogen, sulfur, phosphorus (included in ...
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Papua New Guinea
Papua New Guinea (abbreviated PNG; , ; tpi, Papua Niugini; ho, Papua Niu Gini), officially the Independent State of Papua New Guinea ( tpi, Independen Stet bilong Papua Niugini; ho, Independen Stet bilong Papua Niu Gini), is a country in Oceania that comprises the eastern half of the island of New Guinea and its offshore islands in Melanesia (a region of the southwestern Pacific Ocean north of Australia). Its capital, located along its southeastern coast, is Port Moresby. The country is the world's third largest island country, with an area of . At the national level, after being ruled by three external powers since 1884, including nearly 60 years of Australian administration starting during World War I, Papua New Guinea established its sovereignty in 1975. It became an independent Commonwealth realm in 1975 with Elizabeth II as its queen. It also became a member of the Commonwealth of Nations in its own right. There are 839 known languages of Papua New Guinea, one of ...
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Phytochemicals
Phytochemicals are chemical compounds produced by plants, generally to help them resist fungi, bacteria and plant virus infections, and also consumption by insects and other animals. The name comes . Some phytochemicals have been used as poisons and others as traditional medicine. As a term, ''phytochemicals'' is generally used to describe plant compounds that are under research with unestablished effects on health, and are not scientifically defined as essential nutrients. Regulatory agencies governing food labeling in Europe and the United States have provided guidance for industry to limit or prevent health claims about phytochemicals on food product or nutrition labels. Definition Phytochemicals are chemicals of plant origin. Phytochemicals (from Greek ''phyto'', meaning "plant") are chemicals produced by plants through primary or secondary metabolism. They generally have biological activity in the plant host and play a role in plant growth or defense against competitors ...
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