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Aspergillus Tubingensis
''Aspergillus tubingensis'' is a darkly pigmented species of fungus in the genus ''Aspergillus'' section Nigri. It is often confused with ''Aspergillus niger'' due to their similar morphology and habitat. ''A. tubingensis'' is often involved in food spoilage of fruits and wheat, and industrial fermentation. This species is a rare agent of opportunistic infection. Background ''Aspergillus tubingensis'' was first discovered by Raoul Mosseray in 1934. The conidia are heavily roughened, 3-5 µm in diameter. Whitish to pink sclerotia ranging from 0.5-0.8 mm in diameter are often produced. ''A. tubingensis'' exists exclusively as an asexual fungus but is understood to be phylogenetically closely related to the other so-called black Aspergilli and sexual states in the genus '' Petromyces''. The production of Ochratoxin A (OTA) was previously thought to be a variable character dependent on strain; however, the production of OTA is thought to be a consistent feature with prior ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Czapek Medium
Czapek medium, also called Czapek's agar (CZA) or Czapek-Dox medium, is a growth medium for propagating fungi and other organisms in a laboratory. It was named after its inventors, Czech botanist Friedrich Johann Franz Czapek (May 16, 1868 – July 31, 1921) and American chemist Arthur Wayland Dox (September 19, 1882 – 1954). It was developed to grow ''Aspergillus niger'' and '' Penicillium camemberti''. It works well for many saprophytic fungi and soil bacteria such as species of ''Aspergillus'', '' Candida'', ''Penicillium'', and ''Paecilomyces''. Friedrich Czapek's original recipe is as follows: *1000 g distilled water *30 g cane sugar – energy source and sole source of carbon *1 g dipotassium phosphate – buffering agent *0.5 g magnesium sulfate – source of cations *0.5 g potassium chloride – source of essential ions *0.01 g iron sulfate – source of cations Arthur Wayland Dox added 2 g of sodium nitrate in his version, to p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Croatia
, image_flag = Flag of Croatia.svg , image_coat = Coat of arms of Croatia.svg , anthem = "Lijepa naša domovino"("Our Beautiful Homeland") , image_map = , map_caption = , capital = Zagreb , coordinates = , largest_city = capital , official_languages = Croatian , languages_type = Writing system , languages = Latin , ethnic_groups = , ethnic_groups_year = 2021 , religion = , religion_year = 2021 , demonym = , government_type = Unitary parliamentary republic , leader_title1 = President , leader_name1 = Zoran Milanović , leader_title2 = Prime Minister , leader_name2 = Andrej Plenković , leader_title3 = Speaker of Parliament , leader_name3 = Gordan Jandroković , legislature = Sabor , sovereignty_type ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
China
China, officially the People's Republic of China (PRC), is a country in East Asia. It is the world's most populous country, with a population exceeding 1.4 billion, slightly ahead of India. China spans the equivalent of five time zones and borders fourteen countries by land, the most of any country in the world, tied with Russia. Covering an area of approximately , it is the world's third largest country by total land area. The country consists of 22 provinces, five autonomous regions, four municipalities, and two Special Administrative Regions (Hong Kong and Macau). The national capital is Beijing, and the most populous city and financial center is Shanghai. Modern Chinese trace their origins to a cradle of civilization in the fertile basin of the Yellow River in the North China Plain. The semi-legendary Xia dynasty in the 21st century BCE and the well-attested Shang and Zhou dynasties developed a bureaucratic political system to serve hereditary monarchies, or dyna ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thailand
Thailand ( ), historically known as Siam () and officially the Kingdom of Thailand, is a country in Southeast Asia, located at the centre of the Indochinese Peninsula, spanning , with a population of almost 70 million. The country is bordered to the north by Myanmar and Laos, to the east by Laos and Cambodia, to the south by the Gulf of Thailand and Malaysia, and to the west by the Andaman Sea and the extremity of Myanmar. Thailand also shares maritime borders with Vietnam to the southeast, and Indonesia and India to the southwest. Bangkok is the nation's capital and largest city. Tai peoples migrated from southwestern China to mainland Southeast Asia from the 11th century. Indianised kingdoms such as the Mon, Khmer Empire and Malay states ruled the region, competing with Thai states such as the Kingdoms of Ngoenyang, Sukhothai, Lan Na and Ayutthaya, which also rivalled each other. European contact began in 1511 with a Portuguese diplomatic mission to Ayutthaya, w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chiang Mai
Chiang Mai (, from th, เชียงใหม่ , nod, , เจียงใหม่ ), sometimes written as Chiengmai or Chiangmai, is the largest city in northern Thailand, the capital of Chiang Mai province and the second largest city in Thailand. It is north of Bangkok in a mountainous region called the Thai highlands and has a population of 1.19 million people as of 2022, which is more than 66 percent of the total population of Chiang Mai province (1.8 million). Chiang Mai (meaning "New City" in Thai) was founded in 1296 as the new capital of Lan Na, succeeding the former capital, Chiang Rai. The city's location on the Ping River (a major tributary of the Chao Phraya River) and its proximity to major trading routes contributed to its historic importance. The city (''thesaban nakhon'', Thesaban#City-municipality, "city municipality") of Chiang Mai officially only covers most parts (40,2 km²) of the Mueang Chiang Mai district in the city centre and has a pop ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Water Activity
Water activity (''aw'') is the partial vapor pressure of water in a solution divided by the standard state partial vapor pressure of water. In the field of food science, the standard state is most often defined as pure water at the same temperature. Using this particular definition, pure distilled water has a water activity of exactly one. Water activity is the thermodynamic activity of water as solvent and the relative humidity of the surrounding air after equilibration. As temperature increases, ''aw'' typically increases, except in some products with crystalline salt or sugar. Water migrates from areas of high ''aw'' to areas of low ''aw''. For example, if honey (''aw'' ≈ 0.6) is exposed to humid air (''aw'' ≈ 0.7), the honey absorbs water from the air. If salami (''aw'' ≈ 0.87) is exposed to dry air (''aw'' ≈ 0.5), the salami dries out, which could preserve it or spoil it. Lower ''aw'' substances tend to support fewer microorganisms since these get desiccated by th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ochratoxin
Ochratoxins are a group of mycotoxins produced by some ''Aspergillus'' species (mainly ''A. ochraceus'' and A. ''carbonarius'', but also by 33% of ''A. niger'' industrial strains) and some ''Penicillium'' species, especially ''P. verrucosum''. Ochratoxin A is the most prevalent and relevant fungal toxin of this group, while ochratoxins B and C are of lesser importance. Ochratoxin A is known to occur in commodities such as cereals, coffee, dried fruit, and red wine. It is possibly a human carcinogen and is of special interest as it can be accumulated in the meat of animals. Exposure to ochratoxins through diet can cause acute toxicity in mammalian kidneys. Exposure to ochratoxin A has been associated with Balkan endemic nephropathy, a kidney disease with high mortality in people living near tributaries of the Danube River in Eastern Europe. It has been suggested that carriers of alleles associated with phenylketonuria may have been protected from spontaneous abortion caused by ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mycotoxin
A mycotoxin (from the Greek μύκης , "fungus" and τοξίνη , "toxin") is a toxic secondary metabolite produced by organisms of kingdom Fungi and is capable of causing disease and death in both humans and other animals. The term 'mycotoxin' is usually reserved for the toxic chemical products produced by fungi that readily colonize crops. Examples of mycotoxins causing human and animal illness include aflatoxin, citrinin, fumonisins, ochratoxin A, patulin, trichothecenes, zearalenone, and ergot alkaloids such as ergotamine. One mold species may produce many different mycotoxins, and several species may produce the same mycotoxin. Production Most fungi are aerobic (use oxygen) and are found almost everywhere in extremely small quantities due to the diminute size of their spores. They consume organic matter wherever humidity and temperature are sufficient. Where conditions are right, fungi proliferate into colonies and mycotoxin levels become high. The reason for the product ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ultraviolet
Ultraviolet (UV) is a form of electromagnetic radiation with wavelength from 10 nanometer, nm (with a corresponding frequency around 30 Hertz, PHz) to 400 nm (750 Hertz, THz), shorter than that of visible light, but longer than X-rays. UV radiation is present in sunlight, and constitutes about 10% of the total electromagnetic radiation output from the Sun. It is also produced by electric arcs and specialized lights, such as mercury-vapor lamps, tanning lamps, and black lights. Although long-wavelength ultraviolet is not considered an ionizing radiation because its photons lack the energy to ionization, ionize atoms, it can cause chemical reactions and causes many substances to glow or fluorescence, fluoresce. Consequently, the chemical and biological effects of UV are greater than simple heating effects, and many practical applications of UV radiation derive from its interactions with organic molecules. Short-wave ultraviolet light damages DNA and sterilizes surf ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
β-tubulin
Tubulin in molecular biology can refer either to the tubulin protein superfamily of globular proteins, or one of the member proteins of that superfamily. α- and β-tubulins polymerize into microtubules, a major component of the eukaryotic cytoskeleton. Microtubules function in many essential cellular processes, including mitosis. Discovery and development of tubulin inhibitors, Tubulin-binding drugs kill cancerous cells by inhibiting microtubule dynamics, which are required for DNA segregation and therefore cell division. #Eukaryotic, In eukaryotes, there are six members of the tubulin superfamily, although not all are present in all species.Turk E, Wills AA, Kwon T, Sedzinski J, Wallingford JB, Stearns "Zeta-Tubulin Is a Member of a Conserved Tubulin Module and Is a Component of the Centriolar Basal Foot in Multiciliated Cells"Current Biology (2015) 25:2177-2183. Both α and β tubulins have a mass of around 50 kDa and are thus in a similar range compared to actin (with a mass o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Calmodulin
Calmodulin (CaM) (an abbreviation for calcium-modulated protein) is a multifunctional intermediate calcium-binding messenger protein expressed in all eukaryotic cells. It is an intracellular target of the secondary messenger Ca2+, and the binding of Ca2+ is required for the activation of calmodulin. Once bound to Ca2+, calmodulin acts as part of a calcium signal transduction pathway by modifying its interactions with various target proteins such as kinases or phosphatases. Structure Calmodulin is a small, highly conserved protein that is 148 amino acids long (16.7 kDa). The protein has two approximately symmetrical globular domains (the N- and C- domains) each containing a pair of EF hand motifs separated by a flexible linker region for a total of four Ca2+ binding sites, two in each globular domain. In the Ca2+-free state, the helices that form the four EF-hands are collapsed in a compact orientation, and the central linker is disordered; in the Ca2+-saturated state, th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
