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Angelo DiGeorge
Angelo Mario DiGeorge (April 15, 1921 – October 11, 2009) was an Italian American physician and pediatric endocrinologist from Philadelphia who pioneered the research on the autosomal dominant immunodeficiency now commonly referred to as DiGeorge syndrome. Early life and education DiGeorge was the son of two Italian immigrants, Antonio DiGiorgio and his wife Emilia (née Taraborelli). He was born in South Philadelphia on April 15, 1921. His teacher at primary school changed his Italian surname DiGiorgio into the "American" DiGeorge. He graduated at the top of his class from South Philadelphia High School for Boys in 1939 and was awarded the White Williams Scholarship at the Temple University, where he graduated with distinction in chemistry in 1943. DiGeorge received his medical degree with honors from Temple University School of Medicine in 1946, and completed his internship at Temple University Hospital. He then left Philadelphia from 1947 to 1949 to serve as captain and Chie ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Philadelphia
Philadelphia, often called Philly, is the largest city in the Commonwealth of Pennsylvania, the sixth-largest city in the U.S., the second-largest city in both the Northeast megalopolis and Mid-Atlantic regions after New York City. Since 1854, the city has been coextensive with Philadelphia County, the most populous county in Pennsylvania and the urban core of the Delaware Valley, the nation's seventh-largest and one of world's largest metropolitan regions, with 6.245 million residents . The city's population at the 2020 census was 1,603,797, and over 56 million people live within of Philadelphia. Philadelphia was founded in 1682 by William Penn, an English Quaker. The city served as capital of the Pennsylvania Colony during the British colonial era and went on to play a historic and vital role as the central meeting place for the nation's founding fathers whose plans and actions in Philadelphia ultimately inspired the American Revolution and the nation's inde ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Board Of Pediatrics
The American Board of Pediatrics (ABP) was founded in 1933. It is one of the 24 certifying boards of the American Board of Medical Specialties (ABMS). The ABP is an independent and nonprofit organization. The ABP's mission is to advance child health by certifying pediatricians who meet standards of excellence and are committed to continuous learning and improvement. Certificates awarded The ABP awards certificates in the following pediatric subspecialty areas: * General Pediatrics * Adolescent Medicine * Cardiology * Child Abuse Pediatrics *Critical Care Medicine * Developmental-Behavioral Pediatrics * Emergency Medicine * Endocrinology * Gastroenterology * Hematology-Oncology * Hospital Medicine * Infectious Diseases * Neonatal-Perinatal Medicine * Nephrology * Pulmonology * Rheumatology The American Board of Pediatrics also awards certificates in conjunction with other specialty boards. Those certificates include: * Hospice and Palliative Medicine * Medical Toxicology * Pedi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Philadelphia Phillies
The Philadelphia Phillies are an American professional baseball team based in Philadelphia. They compete in Major League Baseball (MLB) as a member of the National League (NL) National League East, East division. Since 2004, the team's home stadium has been Citizens Bank Park, located in the South Philadelphia Sports Complex. Founded in 1883, the Philadelphia Phillies are the oldest continuous same-name, same-city franchise in all of American professional sports. The Phillies have won two World Series championships (against the Kansas City Royals in and the Tampa Bay Rays in ), eight National League pennants (the first of which came in 1915), and made 15 playoff appearances. As of November 6, 2022, the team has played 21,209 games, winning 10,022 games and losing 11,187. Since the first modern World Series was played in , the Phillies have played 120 consecutive seasons and 140 seasons since the team's 1883 establishment. Before the Phillies won their first World Series in 19 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stamp Collecting
Stamp collecting is the collecting of postage stamps and related objects. It is an area of philately, which is the study (or combined study and collection) of stamps. It has been one of the world's most popular hobbies since the late nineteenth century with the rapid growth of the postal service, as a never-ending stream of new stamps was produced by countries that sought to advertise their distinctiveness through their stamps. Collecting Stamp collecting is generally accepted as one of the areas that make up the wider subject of philately, which is the study of stamps. A philatelist may, but does not have to, collect stamps. It is not uncommon for the term ''philatelist'' to be used to mean a stamp collector. Many casual stamp collectors accumulate stamps for sheer enjoyment and relaxation without worrying about the tiny details. The creation of a large or comprehensive collection, however, generally requires some philatelic knowledge and will usually contain areas of philate ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Politics
Politics (from , ) is the set of activities that are associated with making decisions in groups, or other forms of power relations among individuals, such as the distribution of resources or status. The branch of social science that studies politics and government is referred to as political science. It may be used positively in the context of a "political solution" which is compromising and nonviolent, or descriptively as "the art or science of government", but also often carries a negative connotation.. The concept has been defined in various ways, and different approaches have fundamentally differing views on whether it should be used extensively or limitedly, empirically or normatively, and on whether conflict or co-operation is more essential to it. A variety of methods are deployed in politics, which include promoting one's own political views among people, negotiation with other political subjects, making laws, and exercising internal and external force, including wa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Performing Arts
The performing arts are arts such as music, dance, and drama which are performed for an audience. They are different from the visual arts, which are the use of paint, canvas or various materials to create physical or static art objects. Performing arts include a range of disciplines which are performed in front of a live audience, including theatre, music, and dance. Theatre, music, dance, object manipulation, and other kinds of performances are present in all human cultures. The history of music and dance date to pre-historic times whereas circus skills date to at least Ancient Egypt. Many performing arts are performed professionally. Performance can be in purpose-built buildings, such as theatres and opera houses, on open air stages at festivals, on stages in tents such as circuses or on the street. Live performances before an audience are a form of entertainment. The development of audio and video recording has allowed for private consumption of the performing arts. The pe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gardening
Gardening is the practice of growing and cultivating plants as part of horticulture. In gardens, ornamental plants are often grown for their flowers, foliage, or overall appearance; useful plants, such as root vegetables, leaf vegetables, fruits, and herbs, are grown for consumption, for use as dyes, or for medicinal or cosmetic use. Gardening ranges in scale from fruit orchards, to long boulevard plantings with one or more different types of shrubs, trees, and herbaceous plants, to residential back gardens including lawns and foundation plantings, all the way to container gardens grown inside or outside. Gardening may be very specialized, with only one type of plant grown, or involve a variety of plants in mixed plantings. It involves an active participation in the growing of plants, and tends to be labor-intensive, which differentiates it from farming or forestry. History Ancient times Forest gardening, a forest-based food production system, is the world's oldest form ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetic Disorder
A genetic disorder is a health problem caused by one or more abnormalities in the genome. It can be caused by a mutation in a single gene (monogenic) or multiple genes (polygenic) or by a chromosomal abnormality. Although polygenic disorders are the most common, the term is mostly used when discussing disorders with a single genetic cause, either in a gene or chromosome. The mutation responsible can occur spontaneously before embryonic development (a ''de novo'' mutation), or it can be Heredity, inherited from two parents who are carriers of a faulty gene (autosomal recessive inheritance) or from a parent with the disorder (autosomal dominant inheritance). When the genetic disorder is inherited from one or both parents, it is also classified as a hereditary disease. Some disorders are caused by a mutation on the X chromosome and have X-linked inheritance. Very few disorders are inherited on the Y linkage, Y chromosome or Mitochondrial disease#Causes, mitochondrial DNA (due to t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Intellectual Disability
Intellectual disability (ID), also known as general learning disability in the United Kingdom and formerly mental retardation,Rosa's Law, Pub. L. 111-256124 Stat. 2643(2010). is a generalized neurodevelopmental disorder characterized by significantly impaired intellectual and adaptive functioning. It is defined by an IQ under 70, in addition to deficits in two or more adaptive behaviors that affect everyday, general living. Intellectual functions are defined under DSM-V as reasoning, problem‑solving, planning, abstract thinking, judgment, academic learning, and learning from instruction and experience, and practical understanding confirmed by both clinical assessment and standardized tests. Adaptive behavior is defined in terms of conceptual, social, and practical skills involving tasks performed by people in their everyday lives. Intellectual disability is subdivided into syndromic intellectual disability, in which intellectual deficits associated with other medical and be ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cleft Palate
A cleft lip contains an opening in the upper lip that may extend into the nose. The opening may be on one side, both sides, or in the middle. A cleft palate occurs when the palate (the roof of the mouth) contains an opening into the nose. The term orofacial cleft refers to either condition or to both occurring together. These disorders can result in feeding problems, speech problems, hearing problems, and frequent ear infections. Less than half the time the condition is associated with other disorders. Cleft lip and palate are the result of tissues of the face not joining properly during development. As such, they are a type of birth defect. The cause is unknown in most cases. Risk factors include smoking during pregnancy, diabetes, obesity, an older mother, and certain medications (such as some used to treat seizures). Cleft lip and cleft palate can often be diagnosed during pregnancy with an ultrasound exam. A cleft lip or palate can be successfully treated with surgery. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Parathyroid Gland
Parathyroid glands are small endocrine glands in the neck of humans and other tetrapods. Humans usually have four parathyroid glands, located on the back of the thyroid gland in variable locations. The parathyroid gland produces and secretes parathyroid hormone in response to a low blood calcium, which plays a key role in regulating the amount of calcium in the blood and within the bones. Parathyroid glands share a similar blood supply, venous drainage, and lymphatic drainage to the thyroid glands. Parathyroid glands are derived from the epithelial lining of the third and fourth pharyngeal pouches, with the superior glands arising from the fourth pouch and the inferior glands arising from the higher third pouch. The relative position of the inferior and superior glands, which are named according to their final location, changes because of the migration of embryological tissues. Hyperparathyroidism and hypoparathyroidism, characterized by alterations in the blood calcium levels ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thymus
The thymus is a specialized primary lymphoid organ of the immune system. Within the thymus, thymus cell lymphocytes or ''T cells'' mature. T cells are critical to the adaptive immune system, where the body adapts to specific foreign invaders. The thymus is located in the upper front part of the chest, in the anterior superior mediastinum, behind the sternum, and in front of the heart. It is made up of two lobes, each consisting of a central medulla and an outer cortex, surrounded by a capsule. The thymus is made up of immature T cells called thymocytes, as well as lining cells called epithelial cells which help the thymocytes develop. T cells that successfully develop react appropriately with MHC immune receptors of the body (called ''positive selection'') and not against proteins of the body (called ''negative selection''). The thymus is largest and most active during the neonatal and pre-adolescent periods. By the early teens, the thymus begins to decrease in size and a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
