Aconitum Soongaricum
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Aconitum Soongaricum
''Aconitum soongaricum'' is a poisonous perennial herbaceous plant species of the genus ''Aconitum''. Distribution and habitat ''Aconitum soongaricum'' is endemic to Kashmir.,''Wang Wencai (王文采), Michael J. Warnock''Aconitum soongoricum Flora of China China, Kyrgyzstan, Kazakhstan (the Dzungarian Alatau, Trans-Ili Alatau and Tarbagatai Mountains), at elevations of 2,500–3,000 meters. The specific name ''soongaricum'' means 'native to Dzungaria' - a region currently forming the northern part of Xinjiang in NW China, but bearing a name meaning 'land of the left-hand (i.e. 'western') Mongols'. Toxicity All parts of the plant contain alkaloids associated with aconitic acid (primarily aconitine), but their concentration depends on the phase of vegetation. Spring shoots before flowering are the richest in alkaloids. Uses ''Aconitum soongaricum'' has anti-inflammatory, antimicrobial, narcotic, antitumor, analgesic and antispasmodic effects. The action is due to alkaloids ...
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Carl Linnaeus
Carl Linnaeus (; 23 May 1707 – 10 January 1778), also known after his ennoblement in 1761 as Carl von Linné Blunt (2004), p. 171. (), was a Swedish botanist, zoologist, taxonomist, and physician who formalised binomial nomenclature, the modern system of naming organisms. He is known as the "father of modern taxonomy". Many of his writings were in Latin; his name is rendered in Latin as and, after his 1761 ennoblement, as . Linnaeus was born in Råshult, the countryside of Småland, in southern Sweden. He received most of his higher education at Uppsala University and began giving lectures in botany there in 1730. He lived abroad between 1735 and 1738, where he studied and also published the first edition of his ' in the Netherlands. He then returned to Sweden where he became professor of medicine and botany at Uppsala. In the 1740s, he was sent on several journeys through Sweden to find and classify plants and animals. In the 1750s and 1760s, he continued to collect an ...
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Dzungaria
Dzungaria (; from the Mongolian language, Mongolian words , meaning 'left hand') is a geographical subregion in Northwest China that corresponds to the northern half of Xinjiang. It is thus also known as Beijiang, which means "Northern Xinjiang". Bounded by the Altai Mountains to the north and the Tian Shan mountain range to the south, Dzungaria covers approximately , and borders Kazakhstan to the west and Mongolia to the east. In contexts prior to the mid-18th century Dzungar genocide, the term "Dzungaria" could cover a wider area, conterminous with the Oirats, Oirat-led Dzungar Khanate. Although Dzungaria is geographically, historically, and ethnically distinct from the Tarim Basin (or Nanjiang, ), the Manchu people, Manchu-led Qing dynasty integrated both areas into one province, Xinjiang. Dzungaria is Xinjiang's center of heavy industry, generates most of the region's GDP, and houses its political capital Ürümqi (Oirat language, Oirat for 'beautiful pasture'). As such, Dzun ...
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Analgesic
An analgesic drug, also called simply an analgesic (American English), analgaesic (British English), pain reliever, or painkiller, is any member of the group of drugs used to achieve relief from pain (that is, analgesia or pain management). It is typically used to induce cooperation with a medical procedure. Analgesics are conceptually distinct from anesthetics, which temporarily reduce, and in some instances eliminate, sensation, although analgesia and anesthesia are neurophysiologically overlapping and thus various drugs have both analgesic and anesthetic effects. Analgesic choice is also determined by the type of pain: For neuropathic pain, traditional analgesics are less effective, and there is often benefit from classes of drugs that are not normally considered analgesics, such as tricyclic antidepressants and anticonvulsants. Various analgesics, such as many NSAIDs, are available over the counter in most countries, whereas various others are prescription drugs owing ...
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Antitumor
Cancer can be treated by surgery, chemotherapy, radiation therapy, hormonal therapy, targeted therapy (including immunotherapy such as monoclonal antibody therapy) and synthetic lethality, most commonly as a series of separate treatments (e.g. chemotherapy before surgery). The choice of therapy depends upon the location and grade of the tumor and the stage of the disease, as well as the general state of the patient (performance status). Cancer genome sequencing helps in determining which cancer the patient exactly has for determining the best therapy for the cancer. A number of experimental cancer treatments are also under development. Under current estimates, two in five people will have cancer at some point in their lifetime. Complete removal of the cancer without damage to the rest of the body (that is, achieving cure with near-zero adverse effects) is the ideal, if rarely achieved, goal of treatment and is often the goal in practice. Sometimes this can be accomplished by sur ...
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Narcotic
The term narcotic (, from ancient Greek ναρκῶ ''narkō'', "to make numb") originally referred medically to any psychoactive compound with numbing or paralyzing properties. In the United States, it has since become associated with opiates and opioids, commonly morphine and heroin, as well as derivatives of many of the compounds found within raw opium latex. The primary three are morphine, codeine, and thebaine (while thebaine itself is only very mildly psychoactive, it is a crucial precursor in the vast majority of semi-synthetic opioids, such as oxycodone or hydrocodone). Legally speaking, the term "narcotic" may be imprecisely defined and typically has negative connotations. When used in a legal context in the U.S., a narcotic drug is totally prohibited, such as heroin, or one that is used in violation of legal regulation (in this word sense, equal to any controlled substance or illicit drug). In the medical community, the term is more precisely defined and genera ...
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Antimicrobial
An antimicrobial is an agent that kills microorganisms or stops their growth. Antimicrobial medicines can be grouped according to the microorganisms they act primarily against. For example, antibiotics are used against bacteria, and antifungals are used against fungi. They can also be classified according to their function. Agents that kill microbes are microbicides, while those that merely inhibit their growth are called bacteriostatic agents. The use of antimicrobial medicines to treat infection is known as antimicrobial chemotherapy, while the use of antimicrobial medicines to prevent infection is known as antimicrobial prophylaxis. The main classes of antimicrobial agents are disinfectants (non-selective agents, such as bleach), which kill a wide range of microbes on non-living surfaces to prevent the spread of illness, antiseptics (which are applied to living tissue and help reduce infection during surgery), and antibiotics (which destroy microorganisms within the body). The ...
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Anti-inflammatory
Anti-inflammatory is the property of a substance or treatment that reduces inflammation or swelling. Anti-inflammatory drugs, also called anti-inflammatories, make up about half of analgesics. These drugs remedy pain by reducing inflammation as opposed to opioids, which affect the central nervous system to block pain signaling to the brain. Nonsteroidal anti-inflammatory drugs Nonsteroidal anti-inflammatory drugs (NSAIDs) alleviate pain by counteracting the cyclooxygenase (COX) enzyme. On its own, COX enzyme synthesizes prostaglandins, creating inflammation. In whole, the NSAIDs prevent the prostaglandins from ever being synthesized, reducing or eliminating the inflammation and resulting pain. Some common examples of NSAIDs are aspirin, ibuprofen, and naproxen. The newer specific COX-inhibitors are not classified together with the traditional NSAIDs, even though they presumably share the same mode of action. On the other hand, there are analgesics that are commonly associat ...
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Aconitine
Aconitine is an alkaloid toxin produced by various plant species belonging to the genus '' Aconitum'' (family Ranunculaceae), known also commonly by the names wolfsbane and monkshood. Monkshood is notorious for its toxic properties. Aconitine is also present in Yunnan Baiyao, a proprietary traditional Chinese medicine. Uses Aconitine was previously used as an antipyretic and analgesic and still has some limited application in herbal medicine, although the narrow therapeutic index makes calculating appropriate dosage difficult. Structure and reactivity Biologically active isolates from '' Aconitum'' and ''Delphinium'' plants are classified as norditerpenoid alkaloids, which are further subdivided based on the presence or absence of the C18 carbon. Aconitine is a C19-norditerpenoid, based on its presence of this C18 carbon. It is barely soluble in water, but very soluble in organic solvents such as chloroform or diethyl ether. Aconitine is also soluble in mixtures of alcohol an ...
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Aconitic Acid
Aconitic acid is an organic acid. The two isomers are ''cis''-aconitic acid and ''trans''-aconitic acid. The conjugate base of ''cis''-aconitic acid, ''cis''-aconitate is an intermediate in the isomerization of citrate to isocitrate in the citric acid cycle. It is acted upon by the enzyme aconitase. Aconitic acid can be synthesized by dehydration of citric acid using sulfuric acid Sulfuric acid (American spelling and the preferred IUPAC name) or sulphuric acid ( Commonwealth spelling), known in antiquity as oil of vitriol, is a mineral acid composed of the elements sulfur, oxygen and hydrogen, with the molecular formu ...: :(HO2CCH2)2C(OH)CO2H → HO2CCH=C(CO2H)CH2CO2H + H2O A mixture of isomers are generated in this way. It was first prepared by thermal dehydration. References {{Citric acid cycle Tricarboxylic acids Enoic acids ...
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Mongols
The Mongols ( mn, Монголчууд, , , ; ; russian: Монголы) are an East Asian ethnic group native to Mongolia, Inner Mongolia in China and the Buryatia Republic of the Russian Federation. The Mongols are the principal member of the large family of Mongolic peoples. The Oirats in Western Mongolia as well as the Buryats and Kalmyks of Russia are classified either as distinct ethno-linguistic groups or subgroups of Mongols. The Mongols are bound together by a common heritage and ethnic identity. Their indigenous dialects are collectively known as the Mongolian language. The ancestors of the modern-day Mongols are referred to as Proto-Mongols. Definition Broadly defined, the term includes the Mongols proper (also known as the Khalkha Mongols), Buryats, Oirats, the Kalmyk people and the Southern Mongols. The latter comprises the Abaga Mongols, Abaganar, Aohans, Baarins, Chahars, Eastern Dorbets, Gorlos Mongols, Jalaids, Jaruud, Kharchins, Khishig ...
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Xinjiang
Xinjiang, SASM/GNC: ''Xinjang''; zh, c=, p=Xīnjiāng; formerly romanized as Sinkiang (, ), officially the Xinjiang Uygur Autonomous Region (XUAR), is an autonomous region of the People's Republic of China (PRC), located in the northwest of the country at the crossroads of Central Asia and East Asia. Being the largest province-level division of China by area and the 8th-largest country subdivision in the world, Xinjiang spans over and has about 25 million inhabitants. Xinjiang borders the countries of Mongolia, Russia, Kazakhstan, Kyrgyzstan, Tajikistan, Afghanistan, Pakistan and India. The rugged Karakoram, Kunlun and Tian Shan mountain ranges occupy much of Xinjiang's borders, as well as its western and southern regions. The Aksai Chin and Trans-Karakoram Tract regions, both administered by China, are claimed by India. Xinjiang also borders the Tibet Autonomous Region and the provinces of Gansu and Qinghai. The most well-known route of the historic Silk Ro ...
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Tarbagatai Mountains
The Tarbagatai Mountains ( mn, , , translit. ''Tarvagatai nuruu'', literally: "range with marmots"; ; kk, Тарбағатай жотасы, ''Tarbağatai jotasy'') are a range of mountains located in the north-western parts of Xinjiang, China, and the Abai Region of East Kazakhstan. The name of the mountain derived from Mongolian word: in Traditional Mongolian alphabet: mn, ( "tarvaga", meaning "marmot") with suffix mn, ( "-tai"; literally "to have" or "with"). Many Tarbagan marmot live in this mountain range. Their name does not have a direct translation from the English in Mongolian, as it would mean "marmot's marmot". An eastern extension of the Tarbagatai is the Saur Range. Drainage As it is common for mountain ranges, there is more precipitation in the Tarbagatai mountains than in the adjacent flatlands. The mountains are thus an important watershed. Streams from the northern slopes of the Tarbagatai flow into Lake Zaysan, which eventually drains (via the Irtysh ...
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