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Atropa
''Atropa'' is a genus of flowering plants in the nightshade family, Solanaceae: tall, calcicole, herbaceous perennials (rhizomatous hemicryptophytes), bearing large leaves and glossy berries particularly dangerous to children, due to their combination of an attractive, cherry-like appearance with a high toxicity. Atropa species favour temperate climates and alkaline soils, often growing in light shade in woodland environments associated with limestone hills and mountains. Their seeds can remain viable in the soil for long periods, germinating when the soil of sites in which plants once grew (but from which plants have long been absent) is disturbed by human activity or by natural causes, e.g. the windthrow of trees (a property shared by the seeds of other Solanaceae in tribe Hyoscyameae e.g. those of Hyoscyamus spp., the henbanes). The best-known member of the genus Atropa is deadly nightshade ('' A. belladonna'') - the poisonous plant ''par excellence'' in the minds of many. The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Atropa Baetica
''Atropa baetica'' is one of Europe's rarest wildflowers. A close relative of the infamous deadly nightshade (''Atropa belladonna'') its specific name derives from that of the Roman province of Hispania Baetica, while its common name refers to the Spanish region of Andalucía – both designating the area in the south of Spain where it is most frequently encountered. It is an attractive, perennial herbaceous plant bearing infundibuliform (i.e. funnel-shaped), yellow or greenish flowers and shiny, black berries. Like the other three (generally accepted) species of Atropa, it is an extremely poisonous plant, containing a variety of tropane alkaloids with anticholinergic, deliriant, antispasmodic and mydriatic properties. Although most populations of the plant are to be found in Spain, it is not wholly confined to the Iberian Peninsula of Europe, occurring also in certain localities in Morocco (e.g. the Talassemtane National Park) and Algeria in the Atlas Mountains (Rif, Tell Atlas a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Atropa Belladonna
''Atropa belladonna'', commonly known as belladonna or deadly nightshade, is a toxic perennial herbaceous plant in the nightshade family Solanaceae, which also includes tomatoes, potatoes, and eggplant (aubergine). It is native to Europe, North Africa, and Western Asia. Its distribution extends from Great Britain in the west to western Ukraine and the Iranian province of Gilan in the east. It is also naturalised or introduced in some parts of Canada and the United States. The foliage and berries are extremely toxic when ingested, containing tropane alkaloids. These toxins include atropine, scopolamine, and hyoscyamine, which cause delirium and hallucinations, and are also used as pharmaceutical anticholinergics. Tropane alkaloids are of common occurrence not only in the Old World tribes Hyoscyameae (to which the genus Atropa belongs) and Mandragoreae, but also in the New World tribe Datureae - all of which belong to the subfamily Solanoideae of the plant family Solanaceae. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Solanaceae
The Solanaceae , or nightshades, are a family of flowering plants that ranges from annual and perennial herbs to vines, lianas, epiphytes, shrubs, and trees, and includes a number of agricultural crops, medicinal plants, spices, weeds, and ornamentals. Many members of the family contain potent alkaloids, and some are highly toxic, but many—including tomatoes, potatoes, eggplant, bell and chili peppers—are used as food. The family belongs to the order Solanales, in the asterid group and class Magnoliopsida ( dicotyledons). The Solanaceae consists of about 98 genera and some 2,700 species, with a great diversity of habitats, morphology and ecology. The name Solanaceae derives from the genus ''Solanum''. The etymology of the Latin word is unclear. The name may come from a perceived resemblance of certain solanaceous flowers to the sun and its rays. At least one species of ''Solanum'' is known as the "sunberry". Alternatively, the name could originate from the Latin verb ''sol ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Atropa Acuminata
''Atropa acuminata'', also known as maitbrand or Indian belladonna, is a close relative of deadly nightshade of Europe and North Africa and, like it, is an extremely poisonous plant valued in medicine for its richness in tropane alkaloids with anticholinergic, deliriant, antispasmodic and mydriatic properties. The specific name ''acuminata'' signifies acuminate i.e. 'tapering to a long point' - in reference to the distinctive shape of the leaves. ''Atropa acuminata'' is native to the Himalayas, being found in Eastern Afghanistan, the North of India and Pakistan : from Balochistan in the West to Kashmir in the East, in an area including also Himachal Pradesh, Uttarakhand (part of Uttar Pradesh until the year 2000) and Pakistan's Azad Jammu and Kashmir. The plant described under the name ''Atropa acuminata'' Royle ex Miers (which may be referable to A. acuminata Royle ex Lindl.) is found also in Eastern Iran and Mongolia Mongolia; Mongolian script: , , ; lit. "Mongol Nation" ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Deliriant
Deliriants are a subclass of hallucinogen. The term was coined in the early 1980s to distinguish these drugs from psychedelics and dissociatives such as LSD and ketamine, respectively, due to their primary effect of causing delirium, as opposed to the more lucid and less disturbed states produced by other types of hallucinogens.Duncan, D. F., and Gold, R. S. (1982). Drugs and the Whole Person. New York: John Wiley & Sons The term generally refers to anticholinergic drugs, which are substances that inhibit the function of the neurotransmitter acetylcholine. Common examples of deliriants include plants of the genera ''Datura'' and ''Brugmansia'' (both containing scopolamine) as well as higher than recommended dosages of diphenhydramine (Benadryl). A number of plant deliriants such as that of the Solanaceae family, particularly in the Americas have been used by some indigenous cultures to reach delirious and altered states for traditions or rituals, such as rites of passage, divin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Atropine
Atropine is a tropane alkaloid and anticholinergic medication used to treat certain types of nerve agent and pesticide poisonings as well as some types of slow heart rate, and to decrease saliva production during surgery. It is typically given intravenously or by injection into a muscle. Eye drops are also available which are used to treat uveitis and early amblyopia. The intravenous solution usually begins working within a minute and lasts half an hour to an hour. Large doses may be required to treat some poisonings. Common side effects include a dry mouth, large pupils, urinary retention, constipation, and a fast heart rate. It should generally not be used in people with angle closure glaucoma. While there is no evidence that its use during pregnancy causes birth defects, that has not been well studied. It is likely safe during breastfeeding. It is an antimuscarinic (a type of anticholinergic) that works by inhibiting the parasympathetic nervous system. Atropine occurs n ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mandragora Officinarum
''Mandragora officinarum'' is the type species of the plant genus '' Mandragora'' in the nightshade family Solanaceae. It is often known as mandrake, although this name is also used for other plants. , sources differed significantly in the species they use for ''Mandragora'' plants native to the Mediterranean region. The main species found around the Mediterranean is called ''Mandragora autumnalis'', the autumn mandrake. In a broader circumscription, all the plants native to the regions around the Mediterranean Sea are placed in ''M. officinarum'', which thus includes ''M. autumnalis''. The names autumn mandrake and Mediterranean mandrake are then used. Whatever the circumscription, ''Mandragora officinarum'' is a perennial herbaceous plant with ovate leaves arranged in a rosette, a thick upright root, often branched, and bell-shaped flowers followed by yellow or orange berries. Because mandrakes contain deliriant hallucinogenic tropane alkaloids (atropine, scopolamine, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hyoscyamine
Hyoscyamine (also known as daturine or duboisine) is a naturally occurring tropane alkaloid and plant toxin. It is a secondary metabolite found in certain plants of the family Solanaceae, including henbane, mandrake, angel's trumpets, jimsonweed, tomato, the sorcerers' tree, and deadly nightshade. It is the levorotary isomer of atropine (third of the three major nightshade alkaloids) and thus sometimes known as levo-atropine. Brand names for hyoscyamine include Symax, HyoMax, Anaspaz, Egazil, Buwecon, Cystospaz, Levsin, Levbid, Levsinex, Donnamar, NuLev, Spacol T/S, and Neoquess. Uses Hyoscyamine is used to provide symptomatic relief of spasms caused by various lower abdominal and bladder disorders including peptic ulcers, irritable bowel syndrome, diverticulitis, pancreatitis, colic, and interstitial cystitis. It has also been used to relieve some heart problems, control some of the symptoms of Parkinson's disease, as well as for control of abnormal respiratory symptoms and " ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Scopolamine
Scopolamine, also known as hyoscine, or Devil's Breath, is a natural or synthetically produced tropane alkaloid and anticholinergic drug that is formally used as a medication for treating motion sickness and postoperative nausea and vomiting. It is also sometimes used before surgery to decrease saliva. When used by injection, effects begin after about 20 minutes and last for up to 8 hours. It may also be used orally and as a transdermal patch since it has been long known to have transdermal bioavailability Scopolamine is in the antimuscarinic family of drugs and works by blocking some of the effects of acetylcholine within the nervous system. Scopolamine was first written about in 1881 and started to be used for anesthesia around 1900. Scopolamine is also the main active component produced by certain plants of the nightshade family, which historically have been used as psychoactive drugs (known as ''deliriants'') due to their antimuscarinic-induced hallucinogenic eff ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Solanum
''Solanum'' is a large and diverse genus of flowering plants, which include three food crops of high economic importance: the potato, the tomato and the eggplant (aubergine, brinjal). It is the largest genus in the nightshade family Solanaceae, comprising around 1,500 species. It also contains the so-called horse nettles (unrelated to the genus of true nettles, ''Urtica''), as well as numerous plants cultivated for their ornamental flowers and fruit. ''Solanum'' species show a wide range of growth habits, such as annuals and perennials, vines, subshrubs, shrubs, and small trees. Many formerly independent genera like '' Lycopersicon'' (the tomatoes) and ''Cyphomandra'' are now included in ''Solanum'' as subgenera or sections. Thus, the genus today contains roughly 1,500–2,000 species. Name The generic name was first used by Pliny the Elder (AD 23–79) for a plant also known as , most likely ''S. nigrum''. Its derivation is uncertain, possibly stemming from the Latin word ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tropane Alkaloid
Tropane alkaloids are a class of bicyclic [3.2.1] alkaloids and secondary metabolites that contain a tropane ring in their chemical structure. Tropane alkaloids occur naturally in many members of the plant family Solanaceae. Certain tropane alkaloids such as cocaine and scopolamine are notorious for their psychoactive effects, related usage and cultural associations. Particular tropane alkaloids such as these have pharmacological properties and can act as anticholinergics or stimulants. Classification Anticholinergics Anticholinergic drugs and deliriants: * Atropine, racemate, racemic hyoscyamine, from the deadly nightshade (''Atropa belladonna'') * Hyoscyamine, the ''levo''-isomer of atropine, from henbane (''Hyoscyamus niger''), mandrake (''Mandragora officinarum'') and the sorcerers' tree (''Latua pubiflora''). * Hyoscine hydrobromide, Scopolamine, from henbane and ''Datura'' species (Jimson weed) All three acetylcholine-inhibiting chemicals can also be found in the leave ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anticholinergic
Anticholinergics (anticholinergic agents) are substances that block the action of the neurotransmitter called acetylcholine (ACh) at synapses in the central and peripheral nervous system. These agents inhibit the parasympathetic nervous system by selectively blocking the binding of ACh to its receptor in nerve cells. The nerve fibers of the parasympathetic system are responsible for the involuntary movement of smooth muscles present in the gastrointestinal tract, urinary tract, lungs, sweat glands, and many other parts of the body. In broad terms, anticholinergics are divided into two categories in accordance with their specific targets in the central and peripheral nervous system and at the neuromuscular junction: antimuscarinic agents, and antinicotinic agents ( ganglionic blockers, neuromuscular blockers). The term "anticholinergic" is typically used to refer to antimuscarinics which competitively inhibit the binding of ACh to muscarinic acetylcholine receptors; such agen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
