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Astrid Research
AstridBio Ltd. is a privately held Biotechnology company with office in Hungary. AstridBio's focus is biobanking software development, data management and analysis for genomics research. Its clients include academic research institutes, pharmaceutical and biotech companies. Products * SmartBiobank is a free, online biobank software designed to help clinicians, lab biologists and researchers to integrate translational research elements into one single system. SmartBiobank can store, manage and analyze biospecimen data, clinical data as well as experimental data. It supports the establishment of population or clinical biobanks as well as patient registries. * Disease Discovery Suites are based on the type of disease that is the focus of the investigation: chronic, rare, malignant and infectious diseases. The purpose of the suites is the biological interpretation of structured NGS data - assisting the researcher in revealing the genetic background of diseases or providing an answer ...
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Privately Held Company
A privately held company (or simply a private company) is a company whose shares and related rights or obligations are not offered for public subscription or publicly negotiated in the respective listed markets, but rather the company's stock is offered, owned, traded, exchanged privately, or Over-the-counter (finance), over-the-counter. In the case of a closed corporation, there are a relatively small number of shareholders or company members. Related terms are closely-held corporation, unquoted company, and unlisted company. Though less visible than their public company, publicly traded counterparts, private companies have major importance in the world's economy. In 2008, the 441 list of largest private non-governmental companies by revenue, largest private companies in the United States accounted for ($1.8 trillion) in revenues and employed 6.2 million people, according to ''Forbes''. In 2005, using a substantially smaller pool size (22.7%) for comparison, the 339 companies on ...
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Transcriptomics
Transcriptomics technologies are the techniques used to study an organism's transcriptome, the sum of all of its RNA transcripts. The information content of an organism is recorded in the DNA of its genome and expressed through transcription. Here, mRNA serves as a transient intermediary molecule in the information network, whilst non-coding RNAs perform additional diverse functions. A transcriptome captures a snapshot in time of the total transcripts present in a cell. Transcriptomics technologies provide a broad account of which cellular processes are active and which are dormant. A major challenge in molecular biology is to understand how a single genome gives rise to a variety of cells. Another is how gene expression is regulated. The first attempts to study whole transcriptomes began in the early 1990s. Subsequent technological advances since the late 1990s have repeatedly transformed the field and made transcriptomics a widespread discipline in biological sciences. There ar ...
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Biotechnology Companies Of Hungary
Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used by Károly Ereky in 1919, meaning the production of products from raw materials with the aid of living organisms. Definition The concept of biotechnology encompasses a wide range of procedures for modifying living organisms according to human purposes, going back to domestication of animals, cultivation of the plants, and "improvements" to these through breeding programs that employ artificial selection and hybridization. Modern usage also includes genetic engineering as well as cell and tissue culture technologies. The American Chemical Society defines biotechnology as the application of biological organisms, systems, or processes by various industries to learning about the science of life and the improvement of the value of materials an ...
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Bioinformatics Companies
{{Dynamic list This is a list of bioinformatics companies that have articles at Wikipedia: * Applied Maths provides the software suite BioNumerics * Astrid Research * BIOBASE * BioBam Bioinformatics creator of Blast2GO * Biomax Informatics AG bioinformatics services. * Biovia (formerly Accelrys). * Chemical Computing Group MOE software for structural modelling * CLC Bio Bioinformatics workbenches. * DNASTAR provides DNA sequence assembly and analysis. * Gene Codes Corporation * Genedata software for data analysis and storage. * GeneTalk web-based services. * GenoCAD * Genomatix * Genostar provides streamlined bioinformatics. * Inte:Ligand * Integromics * Invitae * Invitrogen creator of Vector NTI * Leidos Biomedical Research Inc. formerly SAIC. Services are aimed at the Federal Government market. * MacVector * QIAGEN Silicon Valley (formerly Ingenuity Systems) * Qlucore * Phalanx Biotech Group * SimBioSys created the eHITS software * SRA International services aimed ...
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List Of Bioinformatics Companies
{{Dynamic list This is a list of bioinformatics companies that have articles at Wikipedia: * Applied Maths provides the software suite BioNumerics * Astrid Research * BIOBASE * BioBam Bioinformatics creator of Blast2GO * Biomax Informatics AG bioinformatics services. * Biovia (formerly Accelrys). * Chemical Computing Group MOE software for structural modelling * CLC Bio Bioinformatics workbenches. * DNASTAR provides DNA sequence assembly and analysis. * Gene Codes Corporation * Genedata software for data analysis and storage. * GeneTalk web-based services. * GenoCAD * Genomatix * Genostar provides streamlined bioinformatics. * Inte:Ligand * Integromics * Invitae * Invitrogen creator of Vector NTI * Leidos Biomedical Research Inc. formerly SAIC. Services are aimed at the Federal Government market. * MacVector * QIAGEN Silicon Valley (formerly Ingenuity Systems) * Qlucore * Phalanx Biotech Group * SimBioSys created the eHITS software * SRA International services aim ...
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Data Visualization
Data and information visualization (data viz or info viz) is an interdisciplinary field that deals with the graphic representation of data and information. It is a particularly efficient way of communicating when the data or information is numerous as for example a time series. It is also the study of visual representations of abstract data to reinforce human cognition. The abstract data include both numerical and non-numerical data, such as text and geographic information. It is related to infographics and scientific visualization. One distinction is that it's information visualization when the spatial representation (e.g., the page layout of a graphic design) is chosen, whereas it's scientific visualization when the spatial representation is given. From an academic point of view, this representation can be considered as a mapping between the original data (usually numerical) and graphic elements (for example, lines or points in a chart). The mapping determines how the attri ...
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Data Integration
Data integration involves combining data residing in different sources and providing users with a unified view of them. This process becomes significant in a variety of situations, which include both commercial (such as when two similar companies need to merge their databases) and scientific (combining research results from different bioinformatics repositories, for example) domains. Data integration appears with increasing frequency as the volume (that is, big data) and the need to share existing data explodes. It has become the focus of extensive theoretical work, and numerous open problems remain unsolved. Data integration encourages collaboration between internal as well as external users. The data being integrated must be received from a heterogeneous database system and transformed to a single coherent data store that provides synchronous data across a network of files for clients. A common use of data integration is in data mining when analyzing and extracting informati ...
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Metabolomics
Metabolomics is the scientific study of chemical processes involving metabolites, the small molecule substrates, intermediates, and products of cell metabolism. Specifically, metabolomics is the "systematic study of the unique chemical fingerprints that specific cellular processes leave behind", the study of their small-molecule metabolite profiles. The metabolome represents the complete set of metabolites in a biological cell, tissue, organ, or organism, which are the end products of cellular processes. Messenger RNA (mRNA), gene expression data, and proteomics, proteomic analyses reveal the set of gene products being produced in the cell, data that represents one aspect of cellular function. Conversely, metabolic profiling can give an instantaneous snapshot of the physiology of that cell, and thus, metabolomics provides a direct "functional readout of the physiological state" of an organism. There are indeed quantifiable correlations between the metabolome and the other cellular ...
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Proteomics
Proteomics is the large-scale study of proteins. Proteins are vital parts of living organisms, with many functions such as the formation of structural fibers of muscle tissue, enzymatic digestion of food, or synthesis and replication of DNA. In addition, other kinds of proteins include antibodies that protect an organism from infection, and hormones that send important signals throughout the body. The proteome is the entire set of proteins produced or modified by an organism or system. Proteomics enables the identification of ever-increasing numbers of proteins. This varies with time and distinct requirements, or stresses, that a cell or organism undergoes. Proteomics is an interdisciplinary domain that has benefited greatly from the genetic information of various genome projects, including the Human Genome Project. It covers the exploration of proteomes from the overall level of protein composition, structure, and activity, and is an important component of functional genomics. ...
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Metagenomics
Metagenomics is the study of genetic material recovered directly from environmental or clinical samples by a method called sequencing. The broad field may also be referred to as environmental genomics, ecogenomics, community genomics or microbiomics. While traditional microbiology and microbial genome sequencing and genomics rely upon cultivated clonal cultures, early environmental gene sequencing cloned specific genes (often the 16S rRNA gene) to produce a profile of diversity in a natural sample. Such work revealed that the vast majority of microbial biodiversity had been missed by cultivation-based methods. Because of its ability to reveal the previously hidden diversity of microscopic life, metagenomics offers a powerful lens for viewing the microbial world that has the potential to revolutionize understanding of the entire living world. As the price of DNA sequencing continues to fall, metagenomics now allows microbial ecology to be investigated at a much greater scale ...
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Epigenomics
Epigenomics is the study of the complete set of epigenetic modifications on the genetic material of a cell, known as the epigenome. The field is analogous to genomics and proteomics, which are the study of the genome and proteome of a cell. Epigenetic modifications are reversible modifications on a cell's DNA or histones that affect gene expression without altering the DNA sequence. Epigenomic maintenance is a continuous process and plays an important role in stability of eukaryotic genomes by taking part in crucial biological mechanisms like DNA repair. Plant flavones are said to be inhibiting epigenomic marks that cause cancers. Two of the most characterized epigenetic modifications are DNA methylation and histone modification. Epigenetic modifications play an important role in gene expression and regulation, and are involved in numerous cellular processes such as in differentiation/development and tumorigenesis. The study of epigenetics on a global level has been made possible o ...
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Genomics
Genomics is an interdisciplinary field of biology focusing on the structure, function, evolution, mapping, and editing of genomes. A genome is an organism's complete set of DNA, including all of its genes as well as its hierarchical, three-dimensional structural configuration. In contrast to genetics, which refers to the study of ''individual'' genes and their roles in inheritance, genomics aims at the collective characterization and quantification of ''all'' of an organism's genes, their interrelations and influence on the organism. Genes may direct the production of proteins with the assistance of enzymes and messenger molecules. In turn, proteins make up body structures such as organs and tissues as well as control chemical reactions and carry signals between cells. Genomics also involves the sequencing and analysis of genomes through uses of high throughput DNA sequencing and bioinformatics to assemble and analyze the function and structure of entire genomes. Advances in ...
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