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Antibe Therapeutics
Antibe Therapeutics is a Toronto-based pharmaceutical company that develops pain and inflammation-reducing drugs based on gaseous mediator technology. Antibe was founded by John L. Wallace, also a co-founder of NicOx, the first company to develop drugs utilizing gaseous mediators. Founded in 2009, the company listed on the TSX Venture Exchange in 2013 and was moved to the Toronto Stock Exchange in November 2020. In 2015, Antibe acquired Citagenix, a distributor involved in regenerative medicine. On June 1, 2020, the company announced positive results in the final Phase 2 trial of its first drug. Products The mechanism of action of Antibe's drugs is the delivery of minute amounts of hydrogen sulfide to sites of inflammation within the human body. Hydrogen sulfide has been shown to enhance the resolution of injury and repair of damage arising from tissue inflammation. Antibe's lead drug, otenaproxesul or ATB-346, is a hydrogen sulfide-releasing derivative of naproxen, a co ...
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Publicly Traded Corporation
A public company is a company whose ownership is organized via shares of share capital, stock which are intended to be freely traded on a stock exchange or in Over-the-counter (finance), over-the-counter markets. A public (publicly traded) company can be listed on a stock exchange (listing (finance), listed company), which facilitates the trade of shares, or not (unlisted public company). In some jurisdictions, public companies over a certain size must be listed on an exchange. In most cases, public companies are ''private'' enterprises in the ''private'' sector, and "public" emphasizes their reporting and trading on the public markets. Public companies are formed within the legal systems of particular states, and therefore have associations and formal designations which are distinct and separate in the polity in which they reside. In the United States, for example, a public company is usually a type of corporation (though a corporation need not be a public company), in the Unit ...
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Pre-clinical Development
In drug development, preclinical development, also termed preclinical studies or nonclinical studies, is a stage of research that begins before clinical trials (testing in humans) and during which important feasibility, iterative testing and drug safety data are collected, typically in laboratory animals. The main goals of preclinical studies are to determine a starting, safe dose for first-in-human study and assess potential toxicity of the product, which typically include new medical devices, prescription drugs, and diagnostics. Companies use stylized statistics to illustrate the risks in preclinical research, such as that on average, only one in every 5,000 compounds that enters drug discovery to the stage of preclinical development becomes an approved drug. Types of preclinical research Each class of product may undergo different types of preclinical research. For instance, drugs may undergo pharmacodynamics (what the drug does to the body) (PD), pharmacokinetics (wh ...
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University College, London
, mottoeng = Let all come who by merit deserve the most reward , established = , type = Public research university , endowment = £143 million (2020) , budget = £1.544 billion (2019/20) , chancellor = Anne, Princess Royal(as Chancellor of the University of London) , provost = Michael Spence , head_label = Chair of the council , head = Victor L. L. Chu , free_label = Visitor , free = Sir Geoffrey Vos , academic_staff = 9,100 (2020/21) , administrative_staff = 5,855 (2020/21) , students = () , undergrad = () , postgrad = () , coordinates = , campus = Urban , city = London, England , affiliations = , colours = Purple and blue celeste , nickname ...
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UCSD
The University of California, San Diego (UC San Diego or colloquially, UCSD) is a public university, public Land-grant university, land-grant research university in San Diego, California. Established in 1960 near the pre-existing Scripps Institution of Oceanography, UC San Diego is the southernmost of the ten campuses of the University of California, and offers over 200 undergraduate and graduate degree programs, enrolling 33,096 undergraduate and 9,872 graduate students. The university occupies near the coast of the Pacific Ocean, with the main campus resting on approximately . UC San Diego is ranked among the best universities in the world by major college and university rankings. UC San Diego consists of twelve undergraduate, graduate and professional schools as well as seven undergraduate residential colleges. It received over 140,000 applications for undergraduate admissions in Fall 2021, making it the second most applied-to university in the United States. UC San Diego H ...
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University Of Sao Paulo
A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. Universities typically offer both undergraduate and postgraduate Postgraduate or graduate education refers to academic or professional degrees, certificates, diplomas, or other qualifications pursued by post-secondary students who have earned an undergraduate ( bachelor's) degree. The organization and stru ... programs. In the United States, the designation is reserved for colleges that have a graduate school. The word ''university'' is derived from the Latin ''universitas magistrorum et scholarium'', which roughly means "community of teachers and scholars". The first universities were created in Europe by Catholic Church monks. The University of Bologna (''Università di Bologna''), founded in 1088, is the first university in the sense of: *Being a high degree-awarding institute. *Having independence from the ecclesiastic schools ...
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Gilberto De Nucci
Gilberto De Nucci (born 18 March 1958, Campinas) is a noted Brazilian physician, scientist and university professor in the field of pharmacology. Education He was born in Campinas, state of São Paulo (state), São Paulo, Brazil. His father was a well-known physician in the city. De Nucci studied medicine at the Faculdade de Medicina de Ribeirão Preto, Medical School of Ribeirão Preto of the University of São Paulo, in Ribeirão Preto (graduating in 1981), where he also did his initial scientific studies in the Department of Pharmacology. Soon after graduation he moved to London, England. He worked from 1982 to 1985 with Dr. John R. Vane, 1982 Nobel Prize in Physiology and Medicine, at the Wellcome Research Laboratories, in London, England. His doctoral studies were conducted at the Royal College of Surgeons of England, Royal College of Surgeons, University of London, in 1986, with Prof. Salvador Moncada. From 1986 to 1988 he was senior scientist at Saint Bartholomew's Hospital M ...
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University Of Naples
The University of Naples Federico II ( it, Università degli Studi di Napoli Federico II) is a public university in Naples, Italy. Founded in 1224, it is the oldest public non-sectarian university in the world, and is now organized into 26 departments. It was Europe's first university dedicated to training secular administrative staff, and is one of the oldest academic institutions in continuous operation. Federico II is the third University in Italy by number of students enrolled, but despite its size it is still one of the best universities in Italy and the world, in southern Italy it leads 1st Ranking since it started, being particularly notable for research; in 2015 it was ranked among the top 100 universities in the world by citations per paper. The university is named after its founder Frederick II. In October 2016 the university hosted the first ever Apple IOS Developer Academy and in 2018 the Cisco Digital Transformation Lab. History The university of Naples Federico II ...
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University Of Calgary
The University of Calgary (U of C or UCalgary) is a public research university located in Calgary, Alberta, Canada. The University of Calgary started in 1944 as the Calgary branch of the University of Alberta, founded in 1908, prior to being instituted into a separate, autonomous university in 1966. It is composed of 14 faculties and over 85 research institutes and centres. The main campus is located in the northwest quadrant of the city near the Bow River and a smaller south campus is located in the city centre. The main campus houses most of the research facilities and works with provincial and federal research and regulatory agencies, several of which are housed next to the campus such as the Geological Survey of Canada. The main campus covers approximately . A member of the U15, the University of Calgary is also one of Canada's top research universities (based on the number of Canada Research Chairs). The university has a sponsored research revenue of $380.4 million, wi ...
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Food And Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food safety, tobacco products, caffeine products, dietary supplements, Prescription drug, prescription and Over-the-counter drug, over-the-counter pharmaceutical drugs (medications), vaccines, biopharmaceuticals, blood transfusions, medical devices, electromagnetic radiation emitting devices (ERED), cosmetics, Animal feed, animal foods & feed and Veterinary medicine, veterinary products. The FDA's primary focus is enforcement of the Federal Food, Drug, and Cosmetic Act (FD&C), but the agency also enforces other laws, notably Section 361 of the Public Health Service Act, as well as associated regulations. Much of this regulatory-enforcement work is not d ...
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Pharmaceutical
A medication (also called medicament, medicine, pharmaceutical drug, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease. Drug therapy (pharmacotherapy) is an important part of the medical field and relies on the science of pharmacology for continual advancement and on pharmacy for appropriate management. Drugs are classified in multiple ways. One of the key divisions is by level of control, which distinguishes prescription drugs (those that a pharmacist dispenses only on the order of a physician, physician assistant, or qualified nurse) from over-the-counter drugs (those that consumers can order for themselves). Another key distinction is between traditional small molecule drugs, usually derived from chemical synthesis, and biopharmaceuticals, which include recombinant proteins, vaccines, blood products used therapeutically (such as IVIG), gene therapy, monoclonal antibodies and cell therapy (for instance, stem cell therapies) ...
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China
China, officially the People's Republic of China (PRC), is a country in East Asia. It is the world's most populous country, with a population exceeding 1.4 billion, slightly ahead of India. China spans the equivalent of five time zones and borders fourteen countries by land, the most of any country in the world, tied with Russia. Covering an area of approximately , it is the world's third largest country by total land area. The country consists of 22 provinces, five autonomous regions, four municipalities, and two Special Administrative Regions (Hong Kong and Macau). The national capital is Beijing, and the most populous city and financial center is Shanghai. Modern Chinese trace their origins to a cradle of civilization in the fertile basin of the Yellow River in the North China Plain. The semi-legendary Xia dynasty in the 21st century BCE and the well-attested Shang and Zhou dynasties developed a bureaucratic political system to serve hereditary monarchies, or dyna ...
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Nuance Pharma
Nuance may refer to: * Nuance Communications, company that sells voice and productivity software * Music: ** Nuance (American band) Nuance was an American dance music/ freestyle group. It was formed by the producer and arranger, Ron Dean Miller, and featured Vikki Love on vocals. They charted three hits on the US ''Billboard'' Hot Dance Music/Club Play chart in the 1980s, i ..., 1980s dance music group ** Nuance (Canadian band), 1980s pop rock group from Quebec {{Disambiguation ...
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