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Anthony John Clark
Anthony John Clark OBE FRSE (18 September 1951 – 12 August 2004) was an English molecular biologist who was a founder of applying molecular technology to farm animals. He was director of the Roslin Institute from 2002 to 2004. Background Born in Blackpool, Clark's family moved to Lincolnshire and he was educated at Barton Grammar School. He graduated with a degree in natural sciences from Christ's College, Cambridge, a constituent college of the University of Cambridge. He then completed a Masters degree at the University of Western Ontario, with a thesis on the regulation of development in a mudsnail. His PhD on Satellite DNA was conducted at the Medical Research Council (MRC) Unit in Edinburgh. Career After achieving his doctorate, Clark joined John Bishop's team at the Institute of Genetics, University of Edinburgh, where he carried out research into the genes in the liver of mice. In 1985 he was appointed to the Animal Breeding Research Organisation (subsequently ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
John Clark Aka Dr ANthony John Clark
John is a common English name and surname: * John (given name) * John (surname) John may also refer to: New Testament Works * Gospel of John, a title often shortened to John * First Epistle of John, often shortened to 1 John * Second Epistle of John, often shortened to 2 John * Third Epistle of John, often shortened to 3 John People * John the Baptist (died c. AD 30), regarded as a prophet and the forerunner of Jesus Christ * John the Apostle (lived c. AD 30), one of the twelve apostles of Jesus * John the Evangelist, assigned author of the Fourth Gospel, once identified with the Apostle * John of Patmos, also known as John the Divine or John the Revelator, the author of the Book of Revelation, once identified with the Apostle * John the Presbyter, a figure either identified with or distinguished from the Apostle, the Evangelist and John of Patmos Other people with the given name Religious figures * John, father of Andrew the Apostle and Saint Peter * Pope John ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tracy (sheep)
Tracy (1990 – 1997) was a transgenically modified sheep created by scientists at Scotland's Roslin Institute to produce the human protein alpha 1-antitrypsin, a substance regarded in the 1990s as a potential pharmaceutical for the treatments of cystic fibrosis and emphysema. Notably, she is the first transgenic farm mammal ever created. Alpha 1-antitrypsin comprised 50% of the total protein in Tracy's milk, a remarkably high level maintained after lactation. Similar levels were detected in the milk produced by her granddaughters. A deficiency in this protein in humans can produce lung diseases, and its artificial creation was thought to be a potential success in the diseases' treatment. Clinical trials for the engineered protein in 1998 revealed that it developed breathing problems in patients, and research for the milk as a remedy for the diseases has not continued since then.{{cite book, last1=Newton PhD, first1=David E., title=DNA Technology: A Reference Handbook, date=12 N ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2004 Deaths
This is a list of deaths of notable people, organised by year. New deaths articles are added to their respective month (e.g., Deaths in ) and then linked here. 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 See also * Lists of deaths by day The following pages, corresponding to the Gregorian calendar, list the historical events, births, deaths, and holidays and observances of the specified day of the year: Footnotes See also * Leap year * List of calendars * List of non-standard ... * Deaths by year {{DEFAULTSORT:deaths by year ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1951 Births
Events January * January 4 – Korean War: Third Battle of Seoul – Chinese and North Korean forces capture Seoul for the second time (having lost the Second Battle of Seoul in September 1950). * January 9 – The Government of the United Kingdom announces abandonment of the Tanganyika groundnut scheme for the cultivation of peanuts in the Tanganyika Territory, with the writing off of £36.5M debt. * January 15 – In a court in West Germany, Ilse Koch, The "Witch of Buchenwald", wife of the commandant of the Buchenwald concentration camp, is sentenced to life imprisonment. * January 20 – Winter of Terror: Avalanches in the Alps kill 240 and bury 45,000 for a time, in Switzerland, Austria and Italy. * January 21 – Mount Lamington in Papua New Guinea erupts catastrophically, killing nearly 3,000 people and causing great devastation in Oro Province. * January 25 – Dutch author Anne de Vries releases the first volume of his children's novel '' Journey Through ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
British Biologists
British may refer to: Peoples, culture, and language * British people, nationals or natives of the United Kingdom, British Overseas Territories, and Crown Dependencies. ** Britishness, the British identity and common culture * British English, the English language as spoken and written in the United Kingdom or, more broadly, throughout the British Isles * Celtic Britons, an ancient ethno-linguistic group * Brittonic languages, a branch of the Insular Celtic language family (formerly called British) ** Common Brittonic, an ancient language Other uses *''Brit(ish)'', a 2018 memoir by Afua Hirsch *People or things associated with: ** Great Britain, an island ** United Kingdom, a sovereign state ** Kingdom of Great Britain (1707–1800) ** United Kingdom of Great Britain and Ireland (1801–1922) See also * Terminology of the British Isles * Alternative names for the British * English (other) * Britannic (other) * British Isles * Brit (other) * Briton (d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alumni Of Christ's College, Cambridge
Alumni (singular: alumnus (masculine) or alumna (feminine)) are former students of a school, college, or university who have either attended or graduated in some fashion from the institution. The feminine plural alumnae is sometimes used for groups of women. The word is Latin and means "one who is being (or has been) nourished". The term is not synonymous with "graduate"; one can be an alumnus without graduating ( Burt Reynolds, alumnus but not graduate of Florida State, is an example). The term is sometimes used to refer to a former employee or member of an organization, contributor, or inmate. Etymology The Latin noun ''alumnus'' means "foster son" or "pupil". It is derived from PIE ''*h₂el-'' (grow, nourish), and it is a variant of the Latin verb ''alere'' "to nourish".Merriam-Webster: alumnus .. Separate, but from the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Isle Of Colonsay
Colonsay (; gd, Colbhasa; sco, Colonsay) is an island in the Inner Hebrides of Scotland, located north of Islay and south of Mull. The ancestral home of Clan Macfie and the Colonsay branch of Clan MacNeil, it is in the council area of Argyll and Bute and has an area of . Aligned on a south-west to north-east axis, it measures in length and reaches at its widest point. Geology The Colonsay Group, which takes its name from the island, is an estimated sequence of mildly metamorphosed Neoproterozoic sedimentary rocks that also outcrop on the islands of Islay and Oronsay and the surrounding seabed. The sequence has been correlated with the Grampian Group, the oldest part of the Dalradian Supergroup. It includes the metawackes of the Oronsay Greywacke Formation, the sandstones of the Dun Gallain Grit Formation, the metasandstones and metamudstones of the Machrins Arkose, Kilchattan and Milbuie formations, the sandstones and phyllites of the Kiloran Flags Formation and the phyl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Edinburgh
Edinburgh ( ; gd, Dùn Èideann ) is the capital city of Scotland and one of its 32 Council areas of Scotland, council areas. Historically part of the county of Midlothian (interchangeably Edinburghshire before 1921), it is located in Lothian on the southern shore of the Firth of Forth. Edinburgh is Scotland's List of towns and cities in Scotland by population, second-most populous city, after Glasgow, and the List of cities in the United Kingdom, seventh-most populous city in the United Kingdom. Recognised as the capital of Scotland since at least the 15th century, Edinburgh is the seat of the Scottish Government, the Scottish Parliament and the Courts of Scotland, highest courts in Scotland. The city's Holyrood Palace, Palace of Holyroodhouse is the official residence of the Monarchy of the United Kingdom, British monarchy in Scotland. The city has long been a centre of education, particularly in the fields of medicine, Scots law, Scottish law, literature, philosophy, the sc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Canada
Canada is a country in North America. Its ten provinces and three territories extend from the Atlantic Ocean to the Pacific Ocean and northward into the Arctic Ocean, covering over , making it the world's second-largest country by total area. Its southern and western border with the United States, stretching , is the world's longest binational land border. Canada's capital is Ottawa, and its three largest metropolitan areas are Toronto, Montreal, and Vancouver. Indigenous peoples have continuously inhabited what is now Canada for thousands of years. Beginning in the 16th century, British and French expeditions explored and later settled along the Atlantic coast. As a consequence of various armed conflicts, France ceded nearly all of its colonies in North America in 1763. In 1867, with the union of three British North American colonies through Confederation, Canada was formed as a federal dominion of four provinces. This began an accretion of provinces an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Helen Clark (oral Historian)
Helen Clark (8 August 1952 – 14 August 2015) was one of the pioneers of Oral History in Scotland. Biography Helen Clark was born in Lewisham Hospital, London to parents Sheila, a teacher, and Geoffrey Banfield, a manager with Esso Petroleum. She studied Education and History at Cambridge University and in 1973, during her third year there, she met her future husband, Anthony John Clark, a scientist from Lincolnshire, who later became director of the Roslin Institute and was awarded an OBE. With John she had two children Charlie (born 1989) and Laurie (born 1991). After John's death in 2004 she married Jim Kendall in 2011. Helen died on 14 August 2015 after a two-year illness with Motor Neurone Disease. She created a blog to chart her progress and share its effects with others. Career Helen moved to Edinburgh in 1977 where she volunteered at the National Museum before getting her first job as an Art Assistant at the Royal Scottish Museum, now the National Museum of Scot ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cystic Fibrosis
Cystic fibrosis (CF) is a rare genetic disorder that affects mostly the lungs, but also the pancreas, liver, kidneys, and intestine. Long-term issues include difficulty breathing and coughing up mucus as a result of frequent lung infections. Other signs and symptoms may include sinus infections, poor growth, fatty stool, clubbing of the fingers and toes, and infertility in most males. Different people may have different degrees of symptoms. Cystic fibrosis is inherited in an autosomal recessive manner. It is caused by the presence of mutations in both copies of the gene for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. Those with a single working copy are carriers and otherwise mostly healthy. CFTR is involved in the production of sweat, digestive fluids, and mucus. When the CFTR is not functional, secretions which are usually thin instead become thick. The condition is diagnosed by a sweat test and genetic testing. Screening of infants at bi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alpha 1-antitrypsin
Alpha-1 antitrypsin or α1-antitrypsin (A1AT, α1AT, A1A, or AAT) is a protein belonging to the serpin superfamily. It is encoded in humans by the ''SERPINA1'' gene. A protease inhibitor, it is also known as alpha1–proteinase inhibitor (A1PI) or alpha1-antiproteinase (A1AP) because it inhibits various proteases (not just trypsin). In older biomedical literature it was sometimes called serum trypsin inhibitor (STI, dated terminology), because its capability as a trypsin inhibitor was a salient feature of its early study. As a type of enzyme inhibitor, it protects tissues from enzymes of inflammatory cells, especially neutrophil elastase, and has a reference range in blood of 0.9–2.3 g/L (in the US the reference range is expressed as mg/dL or micromoles), but the concentration can rise manyfold upon acute inflammation. When the blood contains inadequate amounts of A1AT or functionally defective A1AT (such as in alpha-1 antitrypsin deficiency), neutrophil elastase is excessi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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