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Anthelminthic
Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. They may also be called vermifuges (those that stun) or vermicides (those that kill). Anthelmintics are used to treat people who are infected by helminths, a condition called helminthiasis. These drugs are also used to treat infected animals. Pills containing anthelmintics are used in mass deworming campaigns of school-aged children in many developing countries. The drugs of choice for soil-transmitted helminths are mebendazole and albendazole; for schistosomiasis and tapeworms it is praziquantel. Types Antiparasitics that specifically target worms of the genus ''Ascaris'' are called ascaricides. * Benzimidazoles: ** Albendazole – effective against threadworms, roundworms, whipworms, tapeworms, hookworms ** Mebendazole – effective against va ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anthelmintic Effect Of Papain On Heligmosomoides Bakeri
Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. They may also be called vermifuges (those that stun) or vermicides (those that kill). Anthelmintics are used to treat people who are infected by helminths, a condition called helminthiasis. These drugs are also used to treat infected animals. Pills containing anthelmintics are used in mass deworming campaigns of school-aged children in many developing countries. The drugs of choice for soil-transmitted helminths are mebendazole and albendazole; for schistosomiasis and tapeworms it is praziquantel. Types Antiparasitics that specifically target worms of the genus ''Ascaris'' are called ascaricides. * Benzimidazoles: ** Albendazole – effective against threadworms, roundworms, whipworms, tapeworms, hookworms ** Mebendazole – effective against va ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tapeworms
Cestoda is a class of parasitic worms in the flatworm phylum (Platyhelminthes). Most of the species—and the best-known—are those in the subclass Eucestoda; they are ribbon-like worms as adults, known as tapeworms. Their bodies consist of many similar units known as proglottids—essentially packages of eggs which are regularly shed into the environment to infect other organisms. Species of the other subclass, Cestodaria, are mainly fish infecting parasites. All cestodes are parasitic; many have complex life histories, including a stage in a definitive (main) host in which the adults grow and reproduce, often for years, and one or two intermediate stages in which the larvae develop in other hosts. Typically the adults live in the digestive tracts of vertebrates, while the larvae often live in the bodies of other animals, either vertebrates or invertebrates. For example, '' Diphyllobothrium'' has at least two intermediate hosts, a crustacean and then one or more freshwater fi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hookworms
Hookworms are intestinal, blood-feeding, parasitic roundworms that cause types of infection known as helminthiases. Hookworm infection is found in many parts of the world, and is common in areas with poor access to adequate water, sanitation, and hygiene. In humans, infections are caused by two main species of roundworm, belonging to the genera ''Ancylostoma'' and '' Necator''. In other animals the main parasites are species of ''Ancylostoma''. Species The two most common types of hookworm that infect humans are ''Ancylostoma duodenale'' and ''Necator americanus''. Hookworm species that are known to infect domestic cats are ''Ancylostoma braziliense'' and ''Ancylostoma tubaeforme''. Wild cats are infected by ''Ancylostoma pluridentatum''. Dogs are commonly infected by ''Ancylostoma caninum'', but may also be infected by ''Uncinaria stenocephala'' and ''Ancylostoma braziliense''. In Asia, ''Ancylostoma ceylanicum'' is endemic among dogs and cats and infects humans. Cattle ar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Helminthiasis
Helminthiasis, also known as worm infection, is any macroparasitic disease of humans and other animals in which a part of the body is infected with parasitic worms, known as helminths. There are numerous species of these parasites, which are broadly classified into tapeworms, flukes, and roundworms. They often live in the gastrointestinal tract of their hosts, but they may also burrow into other organs, where they induce physiological damage. Soil-transmitted helminthiasis and schistosomiasis are the most important helminthiases, and are among the neglected tropical diseases. These group of helminthiases have been targeted under the joint action of the world's leading pharmaceutical companies and non-governmental organizations through a project launched in 2012 called the London Declaration on Neglected Tropical Diseases, which aims to control or eradicate certain neglected tropical diseases by 2020. Helminthiasis has been found to result in poor birth outcome, poor cogniti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Whipworms
''Trichuris trichiura, Trichocephalus trichiuris'' or whipworm, is a parasitic roundworm (a type of helminth) that causes trichuriasis (a type of helminthiasis which is one of the neglected tropical diseases) when it infects a human large intestine. It is commonly known as the ''whipworm'' which refers to the shape of the worm; it looks like a whip with wider "handles" at the posterior end. Life cycle The female ''T. trichiura'' produces 2,000–10,000 single-celled eggs per day. Eggs are deposited from human feces to soil where, after two to three weeks, they become embryonated and enter the "infective" stage. These embryonated infective eggs are ingested by hand-mouth or through formites and hatch in the human small intestine, exploiting the intestinal microflora as a stimulus to hatching. This is the location of growth and molting. The infective larvae penetrate the villi and continue to develop in the small intestine. The young worms move to the caecum and penetrate the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mass Deworming
Mass deworming, also called preventive chemotherapy, is the process of treating large numbers of people, particularly children, for helminthiasis (for example soil-transmitted helminths (STH)) and schistosomiasis in areas with a high prevalence of these conditions. It involves treating everyone – often all children who attend schools, using existing infrastructure to save money – rather than testing first and then only treating selectively. Serious side effects have not been reported when administering the medication to those without worms, and testing for the infection is many times more expensive than treating it. Therefore, for the same amount of money, mass deworming can treat more people more cost-effectively than selective deworming. Mass deworming is one example of mass drug administration. Mass deworming of children can be carried out by administering mebendazole and albendazole which are two types of anthelmintic drug. The cost of providing one tablet every six to twel ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mebendazole
Mebendazole (MBZ), sold under the brand name Vermox among others, is a medication used to treat a number of parasitic worm infestations. This includes ascariasis, pinworm infection, hookworm infections, guinea worm infections, hydatid disease, and giardia, among others. It is taken by mouth. Mebendazole is usually well tolerated. Common side effects include headache, vomiting, and ringing in the ears. If used at large doses it may cause bone marrow suppression. It is unclear if it is safe in pregnancy. Mebendazole is a broad-spectrum antihelminthic agent of the benzimidazole type. Mebendazole came into use in 1971, after it was developed by Janssen Pharmaceutica in Belgium. It is on the World Health Organization's List of Essential Medicines. Mebendazole is available as a generic medication. Medical use Mebendazole is a highly effective, broad-spectrum antihelmintic indicated for the treatment of nematode infestations, including roundworm, hookworm, whipworm, threadworm (pinw ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thiabendazole
Tiabendazole (INN, BAN), also known as thiabendazole (AAN, USAN) or TBZ and the trade names Mintezol, Tresaderm, and Arbotect, is a preservative, an antifungal agent, and an antiparasitic agent. Uses Preservative Tiabendazole is used primarily to control mold, blight, and other fungal diseases in fruits (e.g. oranges) and vegetables; it is also used as a prophylactic treatment for Dutch elm disease. Tiabendazole is also used as a food additive, a preservative with E number E233 (INS number 233). For example, it is applied to bananas to ensure freshness, and is a common ingredient in the waxes applied to the skins of citrus fruits. It is not approved as a food additive in the EU, Australia and New Zealand. Use in treatment of aspergillosis has been reported. It is also used in anti-fungal wallboards as a mixture with azoxystrobin. Parasiticide As an antiparasitic, tiabendazole is able to control roundworms (such as those causing strongyloidiasis), hookworms, and other ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brugia Timori
''Brugia timori'' is a filarial (arthropod-borne) nematode (roundworm) which causes the disease "Timor filariasis", or "Timorian filariasis". While this disease was first described in 1965, the identity of ''Brugia timori'' as the causative agent was not known until 1977. In that same year, '' Anopheles barbirostris'' was shown to be its primary vector. There is no known animal reservoir host. Signs and symptoms Like other human filariasis infections, ''Brugia timori'' filariasis causes acute fever and chronic lymphedema. The life cycle of ''Brugia timori'' is very similar to that of ''Wuchereria bancrofti'' and ''Brugia malayi'', leading to nocturnal periodicity of the disease symptoms. Eosinophilia is common during acute stages of infection. So far ''Brugia timori'' has only been found in the Lesser Sunda Islands of Indonesia. It is locally confined to areas inhabited by its mosquito vector, which breeds in rice fields. One study of the prevalence of infection in Mainang v ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brugia Malayi
''Brugia malayi'' is a filarial (arthropod-borne) nematode (roundworm), one of the three causative agents of lymphatic filariasis in humans. Lymphatic filariasis, also known as elephantiasis, is a condition characterized by swelling of the lower limbs. The two other filarial causes of lymphatic filariasis are ''Wuchereria bancrofti'' and '' Brugia timori'', which both differ from ''B. malayi'' morphologically, symptomatically, and in geographical extent. ''B. malayi'' is transmitted by '' Mansonia'' mosquitoes and is restricted to South and Southeast Asia. It is one of the tropical diseases targeted for elimination by the year 2020 by the World Health Organization, which has spurred vaccine and drug development, as well as new methods of vector control. Signs and symptoms ''B. malayi'' is one of the causative agents of lymphatic filariasis, a condition marked by infection and swelling of the lymphatic system. The disease is primarily caused by the presence of worms in the lympha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wuchereria Bancrofti
''Wuchereria bancrofti'' is a filarial (arthropod-borne) nematode (roundworm) that is the major cause of lymphatic filariasis. It is one of the three parasitic worms, together with ''Brugia malayi'' and '' B. timori'', that infect the lymphatic system to cause lymphatic filariasis. These filarial worms are spread by a variety of mosquito vector species. ''W. bancrofti'' is the most prevalent of the three and affects over 120 million people, primarily in Central Africa and the Nile delta, South and Central America, the tropical regions of Asia including southern China, and the Pacific islands. If left untreated, the infection can develop into lymphatic filariasis. In rare conditions, it also causes tropical pulmonary eosinophilia. No vaccine is commercially available, but high rates of cure have been achieved with various antifilarial regimens and lymphatic filariasis is the target of the World Health Organization Global Program to Eliminate Lymphatic Filariasis with the aim to erad ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diethylcarbamazine
Diethylcarbamazine is a medication used in the treatment of filariasis including lymphatic filariasis, tropical pulmonary eosinophilia, and loiasis. It may also be used for prevention of loiasis in those at high risk. While it has been used for onchocerciasis (river blindness), ivermectin is preferred. It is taken by mouth. Common side effects include itching, facial swelling, headaches, and feeling tired. Other side effects include vision loss and dizziness. It is a recommended treatment in pregnancy and appears to be safe for the baby. The World Health Organization; however, recommends waiting until after pregnancy for treatment when feasible. It is made from 4-methyl-piperazine. Diethylcarbamazine was discovered in 1947 by Yellapragada Subbarow. It is on the World Health Organization's List of Essential Medicines. It is not commercially available in the United States but can be acquired from the Centers for Disease Control and Prevention. Medical uses Diethylcarbamazine is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
