|
Anne E. Carpenter
Anne E. Carpenter is an American scientist in the field of image analysis for cell biology and artificial intelligence for drug discovery. She is the co-creator of CellProfiler, open-source software for high-throughput biological image analysis, and a co-inventor of the Cell Painting assay, a method for image-based profiling. She is an Institute Scientist and Senior Director of the Imaging Platform at the Broad Institute. Education & early career Undergraduate training Carpenter received her B.Sc. in Biological Sciences in 1997 from Purdue University, West Lafayette. During this time, she spent a summer in 1996 as an HHMI Undergraduate Research Fellow in the laboratory of Robert E. Malone at the University of Iowa, working on the control of recombination in yeast. Following her graduation, she spent a summer working on enhancers in Drosophila neural development as a research assistant in the laboratory of Chris Q. Doe, then at the University of Illinois, Urbana-Champaign. G ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kalamazoo, Michigan
Kalamazoo ( ) is a city in the southwest region of the U.S. state of Michigan. It is the county seat of Kalamazoo County. At the 2010 census, Kalamazoo had a population of 74,262. Kalamazoo is the major city of the Kalamazoo-Portage Metropolitan Statistical Area, which had a population of 335,340 in 2015. Kalamazoo is equidistant from Chicago and Detroit, being about 140 miles (225 kilometers) away from both. One of Kalamazoo's most notable features is the Kalamazoo Mall, an outdoor pedestrian shopping mall. The city created the mall in 1959 by closing part of Burdick Street to auto traffic, although two of the mall's four blocks have been reopened to auto traffic since 1999. Kalamazoo is home to Western Michigan University, a large public university, Kalamazoo College, a private liberal arts college, and Kalamazoo Valley Community College, a two-year community college. Name origin Originally known as Bronson (after founder Titus Bronson) in the township of Arcadia, the na ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chris Q
Chris is a short form of various names including Christopher, Christian, Christina, Christine, and Christos. Chris is also used as a name in its own right, however it is not as common. People with the given name *Chris Abani (born 1966), Nigerian author *Chris Abrahams (born 1961), Sydney-based jazz pianist *Chris Adams (other), multiple people *Chris Adcock (born 1989), English internationally elite badminton player *Chris Albright (born 1979), American former soccer player *Chris Alcaide (1923–2004), American actor *Chris Amon (1943–2016), former New Zealand motor racing driver *Chris Andersen (born 1978), American basketball player * Chris Anderson (other), multiple people *Chris Angel (wrestler) (born 1982), Puerto Rican professional wrestler *Chris Anker Sørensen (born 1984), Danish cycler *Chris Anstey (born 1975), Australian basketball player * Chris Anthony, American voice actress *Chris Antley (1966–2000), champion American jockey *Chris Arche ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biologists
A biologist is a scientist who conducts research in biology. Biologists are interested in studying life on Earth, whether it is an individual cell, a multicellular organism, or a community of interacting populations. They usually specialize in a particular branch (e.g., molecular biology, zoology, and evolutionary biology) of biology and have a specific research focus (e.g., studying malaria or cancer). Biologists who are involved in basic research have the aim of advancing knowledge about the natural world. They conduct their research using the scientific method, which is an empirical method for testing hypotheses. Their discoveries may have applications for some specific purpose such as in biotechnology, which has the goal of developing medically useful products for humans. In modern times, most biologists have one or more academic degrees such as a bachelor's degree plus an advanced degree like a master's degree or a doctorate. Like other scientists, biologists can be found w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Computer Scientists
Computer science is the study of computation, automation, and information. Computer science spans theoretical disciplines (such as algorithms, theory of computation, information theory, and automation) to practical disciplines (including the design and implementation of hardware and software). Computer science is generally considered an area of academic research and distinct from computer programming. Algorithms and data structures are central to computer science. The theory of computation concerns abstract models of computation and general classes of problems that can be solved using them. The fields of cryptography and computer security involve studying the means for secure communication and for preventing security vulnerabilities. Computer graphics and computational geometry address the generation of images. Programming language theory considers different ways to describe computational processes, and database theory concerns the management of repositories of data. Human ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Microarrays
A microarray is a multiplex lab-on-a-chip. Its purpose is to simultaneously detect the expression of thousands of genes from a sample (e.g. from a tissue). It is a two-dimensional array on a solid substrate—usually a glass slide or silicon thin-film cell—that assays (tests) large amounts of biological material using high-throughput screening miniaturized, multiplexed and parallel processing and detection methods. The concept and methodology of microarrays was first introduced and illustrated in antibody microarrays (also referred to as antibody matrix) by Tse Wen Chang in 1983 in a scientific publication and a series of patents. The "gene chip" industry started to grow significantly after the 1995 ''Science Magazine'' article by the Ron Davis and Pat Brown labs at Stanford University. With the establishment of companies, such as Affymetrix, Agilent, Applied Microarrays, Arrayjet, Illumina, and others, the technology of DNA microarrays has become the most sophisticated and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MIT Computer Science And Artificial Intelligence Laboratory
Computer Science and Artificial Intelligence Laboratory (CSAIL) is a research institute at the Massachusetts Institute of Technology (MIT) formed by the 2003 merger of the Laboratory for Computer Science (LCS) and the Artificial Intelligence Laboratory (AI Lab). Housed within the Ray and Maria Stata Center, CSAIL is the largest on-campus laboratory as measured by research scope and membership. It is part of the Schwarzman College of Computing but is also overseen by the MIT Vice President of Research. Research activities CSAIL's research activities are organized around a number of semi-autonomous research groups, each of which is headed by one or more professors or research scientists. These groups are divided up into seven general areas of research: * Artificial intelligence * Computational biology * Graphics and vision * Language and learning * Theory of computation * Robotics * Systems (includes computer architecture, databases, distributed systems, networks and networked sy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polina Golland
Polina Golland (born 1971) is an Israeli-American computer scientist specializing in medical image computing and biomedical image analysis. She is Henry Ellis Warren (1894) Professor of Electrical Engineering and Computer Science at the Massachusetts Institute of Technology (MIT), and heads the medical vision group at the MIT Computer Science and Artificial Intelligence Laboratory. Education and career After studying computer science at the Technion – Israel Institute of Technology and earning bachelor's and master's degrees there, Golland went to the Massachusetts Institute of Technology for doctoral study, earning a Ph.D. in 2001 with the dissertation ''Statistical Shape Analysis Of Anatomical Structures'' supervised by Eric Grimson. She joined the MIT faculty in 2003. Recognition Golland was named Henry Ellis Warren (1894) Professor in 2018. She was elected as a Fellow of the American Institute for Medical and Biological Engineering The American Institute for Medical and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Whitehead Institute
Whitehead Institute for Biomedical Research is a non-profit research institute located in Cambridge, Massachusetts, United States that is dedicated to improving human health through basic biomedical research. It was founded as a fiscally independent entity from the Massachusetts Institute of Technology (MIT), where its 18 members all hold faculty appointments in the MIT Department of Biology or the MIT Department of Bioengineering. Two members (Rudolf Jaenisch, 2010, and Robert Weinberg, 1997) are National Medal of Science recipients; ten have been elected to the National Academy of Sciences; and four have been elected to the National Academy of Medicine; six are Howard Hughes Medical Institute Investigators. In September 2019, Ruth Lehmann was announced as the new director of the Whitehead Institute for Biomedical Research, commencing July 2020 and succeeding David Page. History Whitehead Institute was founded in 1982 by industrialist and philanthropist Edwin C. “Jack” ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cell Nucleus
The cell nucleus (pl. nuclei; from Latin or , meaning ''kernel'' or ''seed'') is a membrane-bound organelle found in eukaryotic cells. Eukaryotic cells usually have a single nucleus, but a few cell types, such as mammalian red blood cells, have no nuclei, and a few others including osteoclasts have many. The main structures making up the nucleus are the nuclear envelope, a double membrane that encloses the entire organelle and isolates its contents from the cellular cytoplasm; and the nuclear matrix, a network within the nucleus that adds mechanical support. The cell nucleus contains nearly all of the cell's genome. Nuclear DNA is often organized into multiple chromosomes – long stands of DNA dotted with various proteins, such as histones, that protect and organize the DNA. The genes within these chromosomes are structured in such a way to promote cell function. The nucleus maintains the integrity of genes and controls the activities of the cell by regulating gene expres ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genome
In the fields of molecular biology and genetics, a genome is all the genetic information of an organism. It consists of nucleotide sequences of DNA (or RNA in RNA viruses). The nuclear genome includes protein-coding genes and non-coding genes, other functional regions of the genome such as regulatory sequences (see non-coding DNA), and often a substantial fraction of 'junk' DNA with no evident function. Almost all eukaryotes have mitochondria and a small mitochondrial genome. Algae and plants also contain chloroplasts with a chloroplast genome. The study of the genome is called genomics. The genomes of many organisms have been sequenced and various regions have been annotated. The International Human Genome Project reported the sequence of the genome for ''Homo sapiens'' in 200The Human Genome Project although the initial "finished" sequence was missing 8% of the genome consisting mostly of repetitive sequences. With advancements in technology that could handle sequenci ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fluorescence Microscopy
A fluorescence microscope is an optical microscope that uses fluorescence instead of, or in addition to, scattering, reflection, and attenuation or absorption, to study the properties of organic or inorganic substances. "Fluorescence microscope" refers to any microscope that uses fluorescence to generate an image, whether it is a simple set up like an epifluorescence microscope or a more complicated design such as a confocal microscope, which uses optical sectioning to get better resolution of the fluorescence image. Principle The specimen is illuminated with light of a specific wavelength (or wavelengths) which is absorbed by the fluorophores, causing them to emit light of longer wavelengths (i.e., of a different color than the absorbed light). The illumination light is separated from the much weaker emitted fluorescence through the use of a spectral emission filter. Typical components of a fluorescence microscope are a light source (xenon arc lamp or mercury-vapor lamp are ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
