Angela Tamagnini
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Angela Tamagnini
Angela Tamagnini was a pioneer in the use of smallpox vaccination in Portugal. She also became famous for her role in resisting the French invasion of the city of Tomar in the Santarém District of Portugal during the Napoleonic Wars. Biography Angela Tamagnini was born in Milan, Italy on 26 October 1770. She moved to Portugal in 1783 together with her uncle, Inácio Francisco Tamagnini, who became the doctor of Queen Maria I. In 1795, she married António Florêncio de Abreu e Andrade, son of a rich tobacco and soap trader. Her husband died in 1806. She had one son, João. Her great-grandson was Fernando Tamagnini de Abreu e Silva, the commander of the Portuguese Expeditionary Corps, which fought with the Allies during World War I. During the Peninsular War, in June 1808, the year after the French invasion of Portugal under General Junot, the Portuguese in the northwest of the country rebelled. French troops led by General Margaron were sent to quell the uprising in Tomar. ...
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Milan
Milan ( , , Lombard: ; it, Milano ) is a city in northern Italy, capital of Lombardy, and the second-most populous city proper in Italy after Rome. The city proper has a population of about 1.4 million, while its metropolitan city has 3.26 million inhabitants. Its continuously built-up urban area (whose outer suburbs extend well beyond the boundaries of the administrative metropolitan city and even stretch into the nearby country of Switzerland) is the fourth largest in the EU with 5.27 million inhabitants. According to national sources, the population within the wider Milan metropolitan area (also known as Greater Milan), is estimated between 8.2 million and 12.5 million making it by far the largest metropolitan area in Italy and one of the largest in the EU.* * * * Milan is considered a leading alpha global city, with strengths in the fields of art, chemicals, commerce, design, education, entertainment, fashion, finance, healthcar ...
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Pierre Margaron
Pierre Margaron (1 May 1765 – 16 December 1824) led the French cavalry at the Battle of Vimeiro in 1808. He joined a volunteer battalion in 1792. He rose in rank during the French Revolutionary Wars until he commanded a heavy cavalry regiment in 1798. He led his horsemen at the Trebbia, Novi and Genola in 1799 and Pozzolo and San Massimo in 1800. He became a general of brigade in 1803 and led a corps light cavalry brigade at Austerlitz, Jena and Lübeck. He participated in the 1807 invasion of Portugal and fought at Évora and Vimeiro. From 1810 to 1812 he held a post in the interior. He became a general of division in 1813 and led troops at the Battle of Leipzig. His surname is one of the names inscribed under the Arc de Triomphe, on Column 2. Revolution Margaron was born on 1 May 1765 at Lyon, France. He joined a free company as a temporary captain before the unit was absorbed into the Legion of the Ardennes on 15 August 1792. He was named second chef de bataillon of the ...
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Smallpox Vaccines
Smallpox was an infectious disease caused by variola virus (often called smallpox virus) which belongs to the genus Orthopoxvirus. The last naturally occurring case was diagnosed in October 1977, and the World Health Organization (WHO) certified the global eradication of the disease in 1980, making it the only human disease to be eradicated. The initial symptoms of the disease included fever and vomiting. This was followed by formation of ulcers in the mouth and a skin rash. Over a number of days, the skin rash turned into the characteristic fluid-filled blisters with a dent in the center. The bumps then scabbed over and fell off, leaving scars. The disease was spread between people or via contaminated objects. Prevention was achieved mainly through the smallpox vaccine. Once the disease had developed, certain antiviral medication may have helped. The risk of death was about 30%, with higher rates among babies. Often, those who survived had extensive scarring of their s ...
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1827 Deaths
Eighteen or 18 may refer to: * 18 (number), the natural number following 17 and preceding 19 * one of the years 18 BC, AD 18, 1918, 2018 Film, television and entertainment * ''18'' (film), a 1993 Taiwanese experimental film based on the short story ''God's Dice'' * ''Eighteen'' (film), a 2005 Canadian dramatic feature film * 18 (British Board of Film Classification), a film rating in the United Kingdom, also used in Ireland by the Irish Film Classification Office * 18 (''Dragon Ball''), a character in the ''Dragon Ball'' franchise * "Eighteen", a 2006 episode of the animated television series ''12 oz. Mouse'' Music Albums * ''18'' (Moby album), 2002 * ''18'' (Nana Kitade album), 2005 * '' 18...'', 2009 debut album by G.E.M. Songs * "18" (5 Seconds of Summer song), from their 2014 eponymous debut album * "18" (One Direction song), from their 2014 studio album ''Four'' * "18", by Anarbor from their 2013 studio album '' Burnout'' * "I'm Eighteen", by Alice Cooper commonl ...
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1770 Births
Year 177 ( CLXXVII) was a common year starting on Tuesday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Commodus and Plautius (or, less frequently, year 930 ''Ab urbe condita''). The denomination 177 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire * Lucius Aurelius Commodus Caesar (age 15) and Marcus Peducaeus Plautius Quintillus become Roman Consuls. * Commodus is given the title ''Augustus'', and is made co-emperor, with the same status as his father, Marcus Aurelius. * A systematic persecution of Christians begins in Rome; the followers take refuge in the catacombs. * The churches in southern Gaul are destroyed after a crowd accuses the local Christians of practicing cannibalism. * Forty-seven Christians are martyred in Lyon (Saint Blandina and Pothinus, bishop o ...
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Lisbon Academy Of Sciences
The Lisbon Academy of Sciences ( pt, Academia das Ciências de Lisboa) is Portugal's national academy dedicated to the advancement of sciences and learning, with the goal of promoting academic progress and prosperity in Portugal. It is one of Portugal's most prestigious scientific authorities and the official regulator of the Portuguese language in Portugal, through its Class of Letters. History The academy was founded on 24 December 1779 in Lisbon, Portugal, by João Carlos de Bragança, Duke de Lafões, who served as the academy's first President, and José Correia da Serra, who served as its first secretary-general. Domenico Vandelli was among its mentors and early organizers. The academy received royal patronage under Queen Maria I of Portugal in 1783, bestowing the title of ''Royal Academy of Sciences'' (''Real Academia das Ciências'') unto the institution. The seat of the academy in Lisbon has been located in the Bairro Alto district of Lisbon since 1834. Organization ...
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Coimbra
Coimbra (, also , , or ) is a city and a municipality in Portugal. The population of the municipality at the 2011 census was 143,397, in an area of . The fourth-largest urban area in Portugal after Lisbon, Porto Metropolitan Area, Porto, and Braga, it is the largest city of the Coimbra (district), district of Coimbra and the Centro Region, Portugal, Centro Region. About 460,000 people live in the Região de Coimbra, comprising 19 municipalities and extending into an area of . Among the many archaeological structures dating back to the Roman Empire, Roman era, when Coimbra was the settlement of Aeminium, are its well-preserved aqueduct (watercourse), aqueduct and cryptoporticus. Similarly, buildings from the period when Coimbra was the capital of Portugal (from 1131 to 1255) still remain. During the late Middle Ages, with its decline as the political centre of the Kingdom of Portugal, Coimbra began to evolve into a major cultural centre. This was in large part helped by the establ ...
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Cowpox
Cowpox is an infectious disease caused by the ''cowpox virus'' (CPXV). It presents with large blisters in the skin, a fever and swollen glands, historically typically following contact with an infected cow, though in the last several decades more often (though overall rarely) from infected cats. The hands and face are most frequently affected and the spots are generally very painful. The virus, part of the genus '' Orthopoxvirus'', is closely related to the ''vaccinia'' virus. The virus is zoonotic, meaning that it is transferable between species, such as from cat to human. The transferral of the disease was first observed in dairymaids who touched the udders of infected cows and consequently developed the signature pustules on their hands.Vanessa Ngan, "Viral and Skin Infections"
2009
Cowpox is more com ...
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Edward Jenner
Edward Jenner, (17 May 1749 – 26 January 1823) was a British physician and scientist who pioneered the concept of vaccines, and created the smallpox vaccine, the world's first vaccine. The terms ''vaccine'' and ''vaccination'' are derived from ''Variolae vaccinae'' ('pustules of the cow'), the term devised by Jenner to denote cowpox. He used it in 1798 in the title of his ''Inquiry into the Variolae vaccinae known as the Cow Pox'', in which he described the protective effect of cowpox against smallpox. In the West, Jenner is often called "the father of immunology", and his work is said to have saved "more lives than any other man". In Jenner's time, smallpox killed around 10% of global population, with the number as high as 20% in towns and cities where infection spread more easily. In 1821, he was appointed physician to King George IV of the United Kingdom, George IV, and was also made mayor of Berkeley, Gloucestershire, Berkeley and justice of the peace. A member of the Ro ...
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Variolation
Variolation was the method of inoculation first used to immunize individuals against smallpox (''Variola'') with material taken from a patient or a recently variolated individual, in the hope that a mild, but protective, infection would result. Variolation is no longer used today. It was replaced by the smallpox vaccine, a safer alternative. This in turn led to the development of the many vaccines now available against other diseases. The procedure was most commonly carried out by inserting/rubbing powdered smallpox scabs or fluid from pustules into superficial scratches made in the skin. The virus was normally spread through the air, infecting first the mouth, nose, or respiratory tract, before spreading throughout the body via the lymphatic system. In contrast, infection of the skin usually led to a milder, localized infection, but, crucially, still induced immunity to the virus. The patient would develop pustules like those caused by naturally acquired smallpox. Eventually, after ...
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Porto
Porto or Oporto () is the second-largest city in Portugal, the capital of the Porto District, and one of the Iberian Peninsula's major urban areas. Porto city proper, which is the entire municipality of Porto, is small compared to its metropolitan area, with an estimated population of just 231,800 people in a municipality with only 41.42 km2. Porto's metropolitan area has around 1.7 million people (2021) in an area of ,Demographia: World Urban Areas
March 2010
making it the second-largest urban area in Portugal. It is recognized as a global city with a Gamma + rating from the
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