Andreas Wagner (singer)
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Andreas Wagner (singer)
Andreas Wagner (born 26 January 1967) is an Austrian/US evolutionary biologist and professor at the University of Zürich, Switzerland. He is known for his work on the role of robustness and innovation in biological evolution. Wagner is professor and chairman at the Department of Evolutionary Biology and Environmental Studies at the University of Zürich. Biography Wagner studied biology at the University of Vienna. He received his Ph.D. at Yale University, Department of Biology in 1995. He also holds a M. Phil. from Yale. From 1995 to 1996 he was a fellow at the Institute for Advanced Study Berlin, Germany. From 1998 to 2002 he was assistant professor at the University of New Mexico, Department of Biology and from 2002 to 2012 associate professor (with tenure) at the University of New Mexico, Department of Biology. He was appointed professor at the University of Zürich, Institute of Biochemistry in 2006. In 2011, he joined the Department of Evolutionary Biology and Environ ...
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Evolutionary Biology
Evolutionary biology is the subfield of biology that studies the evolutionary processes (natural selection, common descent, speciation) that produced the diversity of life on Earth. It is also defined as the study of the history of life forms on Earth. Evolution is based on the theory that all species are related and they gradually change over time. In a population, the genetic variations affect the physical characteristics i.e. phenotypes of an organism. These changes in the phenotypes will be an advantage to some organisms, which will then be passed onto their offspring. Some examples of evolution in species over many generations are the Peppered Moth and Flightless birds. In the 1930s, the discipline of evolutionary biology emerged through what Julian Huxley called the modern synthesis of understanding, from previously unrelated fields of biological research, such as genetics and ecology, systematics, and paleontology. The importance of studying Evolutionary biology is ...
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Transcription Factor Binding Site
DNA binding sites are a type of binding site found in DNA where other molecules may bind. DNA binding sites are distinct from other binding sites in that (1) they are part of a DNA sequence (e.g. a genome) and (2) they are bound by DNA-binding proteins. DNA binding sites are often associated with specialized proteins known as transcription factors, and are thus linked to transcriptional regulation. The sum of DNA binding sites of a specific transcription factor is referred to as its cistrome. DNA binding sites also encompasses the targets of other proteins, like restriction enzymes, site-specific recombinases (see site-specific recombination) and methyltransferases. DNA binding sites can be thus defined as short DNA sequences (typically 4 to 30 base pairs long, but up to 200 bp for recombination sites) that are specifically bound by one or more DNA-binding proteins or protein complexes. It has been reported that some binding sites have potential to undergo fast evolutionary chan ...
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1967 Births
Events January * January 1 – Canada begins a year-long celebration of the 100th anniversary of Confederation, featuring the Expo 67 World's Fair. * January 5 ** Spain and Romania sign an agreement in Paris, establishing full consular and commercial relations (not diplomatic ones). ** Charlie Chaplin launches his last film, ''A Countess from Hong Kong'', in the UK. * January 6 – Vietnam War: United States Marine Corps, USMC and Army of the Republic of Vietnam, ARVN troops launch ''Operation Deckhouse Five'' in the Mekong Delta. * January 8 – Vietnam War: Operation Cedar Falls starts. * January 13 – A military coup occurs in Togo under the leadership of Étienne Eyadema. * January 14 – The Human Be-In takes place in Golden Gate Park, San Francisco; the event sets the stage for the Summer of Love. * January 15 ** Louis Leakey announces the discovery of pre-human fossils in Kenya; he names the species ''Proconsul nyanzae, Kenyapithecus africanus''. ** American footbal ...
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Faculty Of 1000
F1000 (formerly "Faculty of 1000") is an open research publisher for scientists, scholars, and clinical researchers. F1000 offers a different research evaluation service from standard academic journals by offering peer-review after, rather than before, publishing a research article. Initially, F1000 was named after the 1,000 faculty members that performed peer-reviews, but over time F1000 expanded to more than 8,000 members. When F1000 was acquired by Taylor & Francis Group in January 2020, it kept the publishing services. F1000Prime (AKA Faculty Opinions) and F1000 Workspace (AKA Sciwheel) were acquired by different brands. History ''Faculty of 1000'' was founded in 2000 by publishing entrepreneur Vitek Tracz in London. Initially, it was named after the 1,000 experts it had reviewing academic works, but over time F1000 expanded to more than 8,000 members. In 2002, it introduced F1000Prime (later known as Faculty Opinions), which recommended scientific articles selected by its ...
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American Association For The Advancement Of Science
The American Association for the Advancement of Science (AAAS) is an American international non-profit organization with the stated goals of promoting cooperation among scientists, defending scientific freedom, encouraging scientific responsibility, and supporting scientific education and science outreach for the betterment of all humanity. It is the world's largest general scientific society, with over 120,000 members, and is the publisher of the well-known scientific journal ''Science''. History Creation The American Association for the Advancement of Science was created on September 20, 1848, at the Academy of Natural Sciences in Philadelphia, Pennsylvania. It was a reformation of the Association of American Geologists and Naturalists. The society chose William Charles Redfield as their first president because he had proposed the most comprehensive plans for the organization. According to the first constitution which was agreed to at the September 20 meeting, the goal of ...
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Technological Evolution
The term "technological evolution" captures explanations of technological change that draw on mechanisms from evolutionary biology. Evolutionary biology has one of its roots in the book “On the origin of species” by Charles Darwin. In the style of this catchphrase, technological evolution might describe the origin of new technologies. Combinatoric theory of technological change The combinatoric theory of technological change states that every technology always consists of simpler technologies and a new technology is made of already existing technologies. One notion of this theory is that this interaction of technologies creates a network. All the technologies which interact to form a new technology can be thought of as complements, such as a screwdriver and a screw which by their interaction create the process of screwing a screw. This newly formed process of screwing a screw can be perceived as a technology itself and can therefore be represented by a new node in the network o ...
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Randomness
In common usage, randomness is the apparent or actual lack of pattern or predictability in events. A random sequence of events, symbols or steps often has no order and does not follow an intelligible pattern or combination. Individual random events are, by definition, unpredictable, but if the probability distribution is known, the frequency of different outcomes over repeated events (or "trials") is predictable.Strictly speaking, the frequency of an outcome will converge almost surely to a predictable value as the number of trials becomes arbitrarily large. Non-convergence or convergence to a different value is possible, but has probability zero. For example, when throwing two dice, the outcome of any particular roll is unpredictable, but a sum of 7 will tend to occur twice as often as 4. In this view, randomness is not haphazardness; it is a measure of uncertainty of an outcome. Randomness applies to concepts of chance, probability, and information entropy. The fields of ...
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Phenotype
In genetics, the phenotype () is the set of observable characteristics or traits of an organism. The term covers the organism's morphology or physical form and structure, its developmental processes, its biochemical and physiological properties, its behavior, and the products of behavior. An organism's phenotype results from two basic factors: the expression of an organism's genetic code, or its genotype, and the influence of environmental factors. Both factors may interact, further affecting phenotype. When two or more clearly different phenotypes exist in the same population of a species, the species is called polymorphic. A well-documented example of polymorphism is Labrador Retriever coloring; while the coat color depends on many genes, it is clearly seen in the environment as yellow, black, and brown. Richard Dawkins in 1978 and then again in his 1982 book ''The Extended Phenotype'' suggested that one can regard bird nests and other built structures such as cad ...
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Genotype
The genotype of an organism is its complete set of genetic material. Genotype can also be used to refer to the alleles or variants an individual carries in a particular gene or genetic location. The number of alleles an individual can have in a specific gene depends on the number of copies of each chromosome found in that species, also referred to as ploidy. In diploid species like humans, two full sets of chromosomes are present, meaning each individual has two alleles for any given gene. If both alleles are the same, the genotype is referred to as homozygous. If the alleles are different, the genotype is referred to as heterozygous. Genotype contributes to phenotype, the observable traits and characteristics in an individual or organism. The degree to which genotype affects phenotype depends on the trait. For example, the petal color in a pea plant is exclusively determined by genotype. The petals can be purple or white depending on the alleles present in the pea plant. Howev ...
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Exaptation
Exaptation and the related term co-option describe a shift in the function of a trait during evolution. For example, a trait can evolve because it served one particular function, but subsequently it may come to serve another. Exaptations are common in both anatomy and behaviour. Bird feathers are a classic example. Initially they may have evolved for temperature regulation, but later were adapted for flight. When feathers were first used to aid in flight, that was an exaptive use. They have since then been shaped by natural selection to improve flight, so in their current state they are best regarded as adaptations for flight. So it is with many structures that initially took on a function as an exaptation: once molded for a new function, they become further adapted for that function. Interest in exaptation relates to both the process and products of evolution: the process that creates complex traits and the products (functions, anatomical structures, biochemicals, etc.) that may b ...
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Adaptation
In biology, adaptation has three related meanings. Firstly, it is the dynamic evolutionary process of natural selection that fits organisms to their environment, enhancing their evolutionary fitness. Secondly, it is a state reached by the population during that process. Thirdly, it is a phenotypic trait or adaptive trait, with a functional role in each individual organism, that is maintained and has evolved through natural selection. Historically, adaptation has been described from the time of the ancient Greek philosophers such as Empedocles and Aristotle. In 18th and 19th century natural theology, adaptation was taken as evidence for the existence of a deity. Charles Darwin proposed instead that it was explained by natural selection. Adaptation is related to biological fitness, which governs the rate of evolution as measured by change in allele frequencies. Often, two or more species co-adapt and co-evolve as they develop adaptations that interlock with those of the oth ...
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Neutral Mutation
Neutral mutations are changes in DNA sequence that are neither beneficial nor detrimental to the ability of an organism to survive and reproduce. In population genetics, mutations in which natural selection does not affect the spread of the mutation in a species are termed neutral mutations. Neutral mutations that are inheritable and not linked to any genes under selection will be lost or will replace all other alleles of the gene. That loss or fixation of the gene proceeds based on random sampling known as genetic drift. A neutral mutation that is in linkage disequilibrium with other alleles that are under selection may proceed to loss or fixation via genetic hitchhiking and/or background selection. While many mutations in a genome may decrease an organism’s ability to survive and reproduce, also known as fitness, those mutations are selected against and are not passed on to future generations. The most commonly-observed mutations that are detectable as variation in the geneti ...
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