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Andrea Crisanti (scientist)
Andrea Crisanti (born 14 September 1954) is an Italian full professor of microbiology at the University of Padua and politician. He previously was professor of Molecular Parasitology at Imperial College London. He is best known for the development of genetically manipulated mosquitoes with the objective to interfere with either their reproductive rate or the capability to transmit diseases such as malaria. Biography Crisanti earned his Master of Medicine and Surgery degree in Italy at Sapienza University of Rome. Crisanti served as a Postdoctoral Fellow at the Center for Molecular Biology (ZMBH) at the University of Heidelberg. In 1994, Crisanti became a lecturer at Imperial College, before being appointed Professor in 2000. He is also the director of the Centre of Functional Genomics at the University of Perugia. He is an author of over 100 scientific publications in leading scientific journals, including ''Proceedings of the National Academy of Sciences of the United States of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Italian Senate
The Senate of the Republic ( it, Senato della Repubblica), or simply the Senate ( it, Senato), is the upper house of the bicameral Italian Parliament (the other being the Chamber of Deputies). The two houses together form a perfect bicameral system, meaning they perform identical functions, but do so separately. Pursuant to the Articles 57, 58, and 59 of the Italian Constitution, the Senate has 200 elective members, of which 196 are elected from Italian constituencies, and 4 from Italian citizens living abroad. Furthermore, there is a small number (currently 6) of senators for life (''senatori a vita''), either appointed or ''ex officio''. It was established in its current form on 8 May 1948, but previously existed during the Kingdom of Italy as ''Senato del Regno'' ( Senate of the Kingdom), itself a continuation of the ''Senato Subalpino'' ( Subalpine Senate) of Sardinia established on 8 May 1848. Members of the Senate are styled ''Senator'' or ''The Honourable Senator'' (Italia ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Science (journal)
''Science'', also widely referred to as ''Science Magazine'', is the peer-reviewed academic journal of the American Association for the Advancement of Science (AAAS) and one of the world's top academic journals. It was first published in 1880, is currently circulated weekly and has a subscriber base of around 130,000. Because institutional subscriptions and online access serve a larger audience, its estimated readership is over 400,000 people. ''Science'' is based in Washington, D.C., United States, with a second office in Cambridge, UK. Contents The major focus of the journal is publishing important original scientific research and research reviews, but ''Science'' also publishes science-related news, opinions on science policy and other matters of interest to scientists and others who are concerned with the wide implications of science and technology. Unlike most scientific journals, which focus on a specific field, ''Science'' and its rival ''Nature (journal), Nature'' c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
COVID-19
Coronavirus disease 2019 (COVID-19) is a contagious disease caused by a virus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first known case was COVID-19 pandemic in Hubei, identified in Wuhan, China, in December 2019. The disease quickly spread worldwide, resulting in the COVID-19 pandemic. The symptoms of COVID‑19 are variable but often include fever, cough, headache, fatigue, breathing difficulties, Anosmia, loss of smell, and Ageusia, loss of taste. Symptoms may begin one to fourteen days incubation period, after exposure to the virus. At least a third of people who are infected Asymptomatic, do not develop noticeable symptoms. Of those who develop symptoms noticeable enough to be classified as patients, most (81%) develop mild to moderate symptoms (up to mild pneumonia), while 14% develop severe symptoms (dyspnea, Hypoxia (medical), hypoxia, or more than 50% lung involvement on imaging), and 5% develop critical symptoms (respiratory failure ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Asymptomatic Carriers
An asymptomatic carrier is a person or other organism that has become infection, infected with a pathogen, but shows no signs or symptoms. Although unaffected by the pathogen, carriers can transmit it to others or develop symptoms in later stages of the disease. Asymptomatic carriers play a critical role in the transmission of common infectious diseases such as Typhoid fever, typhoid, HIV/AIDS, HIV, ''Clostridium difficile infection, C. difficile'', influenzas, cholera, tuberculosis and COVID-19, although the last is often associated with "robust Cell-mediated immunity, T-cell immunity" in more than a quarter of patients studied. While the mechanism of disease-carrying is still unknown, researchers have made progress towards understanding how certain pathogens can remain dormant in a human for a period of time. A better understanding of asymptomatic disease carriers is crucial to the fields of medicine and public health as they work towards mitigating the spread of common infectio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
COVID-19 Pandemic In Italy
The COVID-19 pandemic in Italy is part of the ongoing pandemic of coronavirus disease 2019 () caused by severe acute respiratory syndrome coronavirus 2 (). The virus was first confirmed to have spread to Italy on 31 January 2020, when two Chinese tourists in Rome tested positive for the virus. One week later an Italian man repatriated to Italy from the city of Wuhan, China, was hospitalized and confirmed as the third case in Italy. Clusters of cases were later detected in Lombardy and Veneto on 21 February, with the first deaths on 22 February. By the beginning of March, the virus had spread to all regions of Italy. On 31 January, the Italian government suspended all flights to and from China and declared a state of emergency. In February, eleven municipalities in northern Italy were identified as the centres of the two main Italian clusters and placed under quarantine. The majority of positive cases in other regions traced back to these two clusters. On 8 March 2020, Pr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
European Food Safety Authority
The European Food Safety Authority (EFSA) is the agency of the European Union (EU) that provides independent scientific advice and communicates on existing and emerging risks associated with the food chain. EFSA was established in February 2002, is based in Parma, Italy, and for 2021 it has a budget of €118.6 million, and a total staff of 542. The work of EFSA covers all matters with a direct or indirect impact on food and feed safety, including animal health and welfare, plant protection and plant health and nutrition. EFSA supports the European Commission, the European Parliament and EU member states in taking effective and timely risk management decisions that ensure the protection of the health of European consumers and the safety of the food and feed chain. EFSA also communicates to the public in an open and transparent way on all matters within its remit. Structure Based on a regulation of 2002, the EFSA is composed of four bodies: * Management Board * Executive Dir ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vatican City
Vatican City (), officially the Vatican City State ( it, Stato della Città del Vaticano; la, Status Civitatis Vaticanae),—' * german: Vatikanstadt, cf. '—' (in Austria: ') * pl, Miasto Watykańskie, cf. '—' * pt, Cidade do Vaticano—' * es, Ciudad del Vaticano—' is an independent city-state, microstate and enclave and exclave, enclave within Rome, Italy. Also known as The Vatican, the state became independent from Italy in 1929 with the Lateran Treaty, and it is a distinct territory under "full ownership, exclusive dominion, and sovereign authority and jurisdiction" of the Holy See, itself a Sovereignty, sovereign entity of international law, which maintains the city state's Temporal power of the Holy See, temporal, Foreign relations of the Holy See, diplomatic, and spiritual Legal status of the Holy See, independence. With an area of and a 2019 population of about 453, it is the smallest state in the world both by area and List of countries and dependencies ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pathogens And Global Health
''Pathogens and Global Health'' is a peer-reviewed medical journal published by Taylor & Francis. It covers tropical diseases, including their microbiology, epidemiology and molecular biology, as well as medical entomology, HIV/AIDS, malaria, and tuberculosis. The editor-in-chief is Andrea Crisanti (Imperial College London). History The journal was established by Sir Ronald Ross in 1906 as ''Annals of Tropical Medicine and Parasitology'' to share the results of the Liverpool School of Tropical Medicine's research and field expeditions. In May 2011, the journal was purchased by Maney Publishing, obtaining its current title in 2012, reflecting a broader focus including the biology, immunology, genetics, treatment, and control of pathogens of medical relevance beyond a regional definition. Abstracting and indexing The journal is abstracted and indexed in: According to the ''Journal Citation Reports'', the journal has a 2021 impact factor The impact factor (IF) or journal impa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Annals Of Tropical Medicine And Parasitology
''Pathogens and Global Health'' is a peer-reviewed medical journal published by Taylor & Francis. It covers tropical diseases, including their microbiology, epidemiology and molecular biology, as well as medical entomology, HIV/AIDS, malaria, and tuberculosis. The editor-in-chief is Andrea Crisanti (Imperial College London). History The journal was established by Sir Ronald Ross in 1906 as ''Annals of Tropical Medicine and Parasitology'' to share the results of the Liverpool School of Tropical Medicine's research and field expeditions. In May 2011, the journal was purchased by Maney Publishing, obtaining its current title in 2012, reflecting a broader focus including the biology, immunology, genetics, treatment, and control of pathogens of medical relevance beyond a regional definition. Abstracting and indexing The journal is abstracted and indexed in: According to the ''Journal Citation Reports'', the journal has a 2021 impact factor The impact factor (IF) or journal impac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Doublesex
''Doublesex'' (''dsx'') is a gene that is involved in the sex determination system of many insects including the fruit fly ''Drosophila melanogaster''. Sex determination The gene is expressed in both male and female flies and is subject to alternative splicing, producing the protein isoforms ''dsxf'' in females and the longer ''dsxm'' in males. The production of ''dsxf'' is caused by the presence of the female-specific version of the ''transformer'' (''tra'') gene. In a sense, the isoform of ''dsx'' informs a cell about the organism's sex; for instance, female genitals only develop if ''dsxf'' is present. In conjunction with the gene ''fruitless'', ''dsx'' also causes differences in the brain structure and behavior of males and females. Lay summary: Although the details of sex determination differ in the various species, there is a gene related to ''dsx'' in vertebrates (DMRT1) and in nematodes ( MAB-3). All of these are transcription factor In molecular biology, a tra ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
CRISPR Gene Editing
CRISPR gene editing (pronounced "crisper") is a genetic engineering technique in molecular biology by which the genomes of living organisms may be modified. It is based on a simplified version of the bacterial CRISPR-Cas9 antiviral defense system. By delivering the Cas9 nuclease complexed with a synthetic guide RNA (gRNA) into a cell, the cell's genome can be cut at a desired location, allowing existing genes to be removed and/or new ones added ''in vivo''. The technique is considered highly significant in biotechnology and medicine as it enables editing genomes ''in vivo'' very precisely, cheaply, and easily. It can be used in the creation of new medicines, agricultural products, and genetically modified organisms, or as a means of controlling pathogens and pests. It also has possibilities in the treatment of inherited genetic diseases as well as diseases arising from somatic mutations such as cancer. However, its use in human germline genetic modification is highly controve ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene Transfer
Horizontal gene transfer (HGT) or lateral gene transfer (LGT) is the movement of genetic material between unicellular and/or multicellular organisms other than by the ("vertical") transmission of DNA from parent to offspring ( reproduction). HGT is an important factor in the evolution of many organisms. HGT is influencing scientific understanding of higher order evolution while more significantly shifting perspectives on bacterial evolution. Horizontal gene transfer is the primary mechanism for the spread of antibiotic resistance in bacteria, and plays an important role in the evolution of bacteria that can degrade novel compounds such as human-created pesticides and in the evolution, maintenance, and transmission of virulence. It often involves temperate bacteriophages and plasmids. Genes responsible for antibiotic resistance in one species of bacteria can be transferred to another species of bacteria through various mechanisms of HGT such as transformation, transduction ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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