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AllTrials
AllTrials (sometimes called All Trials or AllTrials.net) is a project advocating that clinical research adopt the principles of open research. The project summarizes itself as "All trials registered, all results reported": that is, all clinical trials should be listed in a clinical trials registry, and their results should always be shared as open data. At the center of the organisation is a petition signed by over 85,000 individuals and 599 organisations (as of August 2015): Ben Goldacre, author of '' Bad Science'' and '' Bad Pharma'', is a founder of the campaign and its most public spokesperson. In 2016 he participated in the launch of the OpenTrials database. AllTrials is an international initiative of Bad Science, '' BMJ'', Centre for Evidence-based Medicine, Cochrane Collaboration, James Lind Initiative, ''PLOS'' and Sense about Science and is being led in the US by Sense about Science USA, Dartmouth's Geisel School of Medicine and the Dartmouth Institute for Health Pol ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bad Pharma
''Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients'' is a book by the British physician and academic Ben Goldacre about the pharmaceutical industry, its relationship with the medical profession, and the extent to which it controls academic research into its own products.Luisa Dillner"Bad Pharma by Ben Goldacre – review" ''The Guardian'', 17 October 2012. It was published in the UK in September 2012 by the Fourth Estate imprint of HarperCollins, and in the United States in February 2013 by Faber and Faber. Goldacre argues in the book that "the whole edifice of medicine is broken", because the evidence on which it is based is systematically distorted by the pharmaceutical industry. He writes that the industry finances most of the clinical trials into its own products and much of doctors' continuing education, that clinical trials are often conducted on small groups of unrepresentative subjects and negative data is routinely withheld, and that apparently independe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ben Goldacre
Ben Michael Goldacre (born 20 May 1974) is a British physician, academic and science writer. He is the first Bennett Professor of Evidence-Based Medicine and director of the Bennett Institute for Applied Data Science at the University of Oxford. He is a founder of the AllTrials campaign and OpenTrials to require open science practices in clinical trials. Goldacre is known in particular for his ''Bad Science'' column in ''The Guardian'', which he wrote between 2003 and 2011, and is the author of four books: '' Bad Science'' (2008), a critique of irrationality and certain forms of alternative medicine; '' Bad Pharma'' (2012), an examination of the pharmaceutical industry, its publishing and marketing practices, and its relationship with the medical profession; ''I Think You'll Find It's a Bit More Complicated Than That'', a collection of his journalism; and ''Statins'', about evidence-based medicine. Goldacre frequently delivers free talks about bad science; he describes himself ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Centre For Evidence-Based Medicine
The Centre for Evidence-Based Medicine (CEBM), based in the Nuffield Department of Primary Care Health Sciences at the University of Oxford, is an academic-led centre dedicated to the practice, teaching, and dissemination of high quality evidence-based medicine to improve healthcare in everyday clinical practice. CEBM was founded by David Sackett in 1995. It was subsequently directed by Brian Haynes and Paul Glasziou. Since 2010 it has been led by Professor Carl Heneghan, a clinical epidemiologist and general practitioner. There are currently over 25 active staff and honorary members of the CEBM. The staff include clinicians, statisticians, epidemiologists, information specialists, quantitative and qualitative researchers. Teaching and degrees CEBM is the academic lead for Oxford University's Graduate School in Evidence-Based Healthcare, together with the university's Department of Continuing Education. The Graduate School includes a MSc in Evidence-Based Health Care and a DP ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clinical Trials Registry
Preregistration is the practice of registering the hypotheses, methods, and/or analyses of a scientific study before it is conducted. This can include analyzing primary data or secondary data. Clinical trial registration is similar, although it may not require the registration of a study's analysis protocol. Finally, registered reports include the peer review and in principle acceptance of a study protocol prior to data collection. Preregistration assists in the identification and/or reduction of a variety of potentially problematic research practices, including p-hacking, publication bias, data dredging, inappropriate forms of post hoc analysis, and (relatedly) HARKing. It has recently gained prominence in the open science community as a potential solution to some of the issues that are thought to underlie the replication crisis. However, critics have argued that it may not be necessary when other open science practices are implemented such as Registered Reports. Types Standa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Publication Bias
In published academic research, publication bias occurs when the outcome of an experiment or research study biases the decision to publish or otherwise distribute it. Publishing only results that show a significant finding disturbs the balance of findings in favor of positive results. The study of publication bias is an important topic in metascience. Despite similar quality of execution and design, papers with statistically significant results are three times more likely to be published than those with null results. This unduly motivates researchers to manipulate their practices to ensure statistically significant results, such as by data dredging. Many factors contribute to publication bias. For instance, once a scientific finding is well established, it may become newsworthy to publish reliable papers that fail to reject the null hypothesis. Most commonly, investigators simply decline to submit results, leading to non-response bias. Investigators may also assume they made a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clinical Trials Registry
Preregistration is the practice of registering the hypotheses, methods, and/or analyses of a scientific study before it is conducted. This can include analyzing primary data or secondary data. Clinical trial registration is similar, although it may not require the registration of a study's analysis protocol. Finally, registered reports include the peer review and in principle acceptance of a study protocol prior to data collection. Preregistration assists in the identification and/or reduction of a variety of potentially problematic research practices, including p-hacking, publication bias, data dredging, inappropriate forms of post hoc analysis, and (relatedly) HARKing. It has recently gained prominence in the open science community as a potential solution to some of the issues that are thought to underlie the replication crisis. However, critics have argued that it may not be necessary when other open science practices are implemented such as Registered Reports. Types Standa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Skeptical Inquirer
''Skeptical Inquirer'' is a bimonthly American general-audience magazine published by the Committee for Skeptical Inquiry (CSI) with the subtitle: ''The Magazine for Science and Reason''. Mission statement and goals Daniel Loxton, writing in 2013 about the mission and goals of the skeptical movement, criticized the idea that people wanted to read about the paranormal, Uri Geller and crystal skulls not being relevant any longer. Paul Kurtz in 2009 seemed to share this sentiment and stated that the organization would still research some paranormal subjects as they have expertise in this area, but they would begin to investigate other areas. S.I. "has reached an historic juncture: the recognition that there is a critical need to change our direction." While editor Frazier did expand the scope of the magazine to include topics less paranormal and more that were an attack on science and critical thinking such as climate change denialism, conspiracy theories and the influence of the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Business News Network
BNN Bloomberg (formerly Business News Network and Report on Business Television) is a Canadian English language specialty channel owned by Bell Media. It broadcasts programming related to business and financial news and analysis. The channel is headquartered at 299 Queen Street West in Downtown Toronto. Since April 30, 2018, the network has operated as a partner of the U.S. business channel Bloomberg Television, although BNN still produces a large portion of its business day programming in-house. Much of the channel's programming is also simulcast by radio stations CFTE in Vancouver and CKOC in Hamilton under the branding ''BNN Bloomberg Radio''. History As Report on Business Television (RoBTV) The network was licensed by the Canadian Radio-television and Telecommunications Commission (CRTC) in 1996 to a joint venture of Thomson Corporation (50%), Western International Communications (25%) and Cancom (25%). It launched on September 1, 1999 as ''Report on Business Television'' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Analytical Bias
Statistical bias is a systematic tendency which causes differences between results and facts. The bias exists in numbers of the process of data analysis, including the source of the data, the estimator chosen, and the ways the data was analyzed. Bias may have a serious impact on results, for example, to investigate people's buying habits. If the sample size is not large enough, the results may not be representative of the buying habits of all the people. That is, there may be discrepancies between the survey results and the actual results. Therefore, understanding the source of statistical bias can help to assess whether the observed results are close to the real results. Bias can be differentiated from other mistakes such as accuracy (instrument failure/inadequacy), lack of data, or mistakes in transcription (typos). Bias implies that the data selection may have been skewed by the collection criteria. Bias does not preclude the existence of any other mistakes. One may have a poo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chicago Tribune
The ''Chicago Tribune'' is a daily newspaper based in Chicago, Illinois, United States, owned by Tribune Publishing. Founded in 1847, and formerly self-styled as the "World's Greatest Newspaper" (a slogan for which WGN radio and television are named), it remains the most-read daily newspaper in the Chicago metropolitan area and the Great Lakes region. It had the sixth-highest circulation for American newspapers in 2017. In the 1850s, under Joseph Medill, the ''Chicago Tribune'' became closely associated with the Illinois politician Abraham Lincoln, and the Republican Party's progressive wing. In the 20th century under Medill's grandson, Robert R. McCormick, it achieved a reputation as a crusading paper with a decidedly more American-conservative anti-New Deal outlook, and its writing reached other markets through family and corporate relationships at the ''New York Daily News'' and the ''Washington Times-Herald.'' The 1960s saw its corporate parent owner, Tribune Company, rea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Committee For Skeptical Inquiry
The Committee for Skeptical Inquiry (CSI), formerly known as the Committee for the Scientific Investigation of Claims of the Paranormal (CSICOP), is a program within the US non-profit organization Center for Inquiry (CFI), which seeks to "promote scientific inquiry, critical investigation, and the use of reason in examining controversial and extraordinary claims." Paul Kurtz proposed the establishment of CSICOP in 1976 as an independent non-profit organization (before merging with CFI as one of its programs in 2015), to counter what he regarded as an uncritical acceptance of, and support for, paranormal claims by both the media and society in general. Its philosophical position is one of scientific skepticism. CSI's fellows have included notable scientists, Nobel laureates, philosophers, psychologists, educators and authors. It is headquartered in Amherst, New York. History The committee was officially launched on April 30, 1976, and was co-chaired by Paul Kurtz and Marcell ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
New York, NY
New York, often called New York City or NYC, is the List of United States cities by population, most populous city in the United States. With a 2020 population of 8,804,190 distributed over , New York City is also the List of United States cities by population density, most densely populated major city in the United States, and is more than twice as populous as second-place Los Angeles. New York City lies at the southern tip of New York (state), New York State, and constitutes the geographical and demographic center of both the Northeast megalopolis and the New York metropolitan area, the largest metropolitan area in the world by urban area, urban landmass. With over 20.1 million people in its metropolitan statistical area and 23.5 million in its combined statistical area as of 2020, New York is one of the world's most populous Megacity, megacities, and over 58 million people live within of the city. New York City is a global city, global Culture of New ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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