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Adrian John Brown
Adrian John Brown, FRS (27 April 1852 – 2 July 1919) was a British Professor of Malting and Brewing at the University of Birmingham and a pioneer in the study of enzyme kinetics. He was born at Burton-on-Trent, Staffordshire to Edwin Brown, a bank manager in the town. His elder brother was Horace Tabberer Brown. He attended the local grammar school and then went up to study chemistry at the Royal College of Science in London. He became private assistant to Dr Russell at St Bartholomew's Hospital Medical School. In 1873 he returned to Burton to work as a chemist in the brewing industry for the next twenty-five years. In 1899 he left to become Professor of Brewing and Malting at Mason University College (which became Birmingham University in 1900). He studied the rate of fermentation of sucrose by yeast and suggested in 1892 that a substance in the yeast might be responsible for speeding up the reaction. This was the first time enzymes were suggested as separate entities fr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
St Bartholomew's Hospital
St Bartholomew's Hospital, commonly known as Barts, is a teaching hospital located in the City of London. It was founded in 1123 and is currently run by Barts Health NHS Trust. History Early history Barts was founded in 1123 by Rahere (died 1144, and entombed in the nearby Priory Church of St Bartholomew the Great), a favourite courtier of King Henry I. The dissolution of the monasteries did not affect the running of Barts as a hospital, but left it in a precarious position by removing its income. It was refounded by King Henry VIII in December 1546, on the signing of an agreement granting the hospital to the Corporation of London.''St Bartholomew's Hospital'' ''Old and New London'': Volume 2 (1878), pp. 359–363. Retrieved 30 January 2009 The hospital became legally styled as the "House of the Poore ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Birmingham
, mottoeng = Through efforts to heights , established = 1825 – Birmingham School of Medicine and Surgery1836 – Birmingham Royal School of Medicine and Surgery1843 – Queen's College1875 – Mason Science College1898 – Mason University College1900 – gained university status by royal charter , city = Birmingham , province = West Midlands , country = England, UK , coor = , campus = Urban, suburban , academic_staff = 5,495 (2020) , administrative_staff = , head_label = Visitor , head = The Rt Hon Penny Mordaunt MP , chancellor = Lord Bilimoria , vice_chancellor = Adam Tickell , type = Public , endowment = £134.5 million (2021) , budget = £774.1 million (2020–21) , students = () , undergrad = () , postgrad = () , affiliations = Universitas 21Universities UK EUA ACUSutton 13Russell Group , free_label = , free = , colours = The University , website = , logo = The University of Birmingham (informally Birmingham University) i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Enzyme Kinetics
Enzyme kinetics is the study of the rates of enzyme-catalysed chemical reactions. In enzyme kinetics, the reaction rate is measured and the effects of varying the conditions of the reaction are investigated. Studying an enzyme's kinetics in this way can reveal the catalytic mechanism of this enzyme, its role in metabolism, how its activity is controlled, and how a drug or a modifier ( inhibitor or activator) might affect the rate. An enzyme (E) is typically a protein molecule that promotes a reaction of another molecule, its substrate (S). This binds to the active site of the enzyme to produce an enzyme-substrate complex ES, and is transformed into an enzyme-product complex EP and from there to product P, via a transition state ES*. The series of steps is known as the mechanism: : E + S ⇄ ES ⇄ ES* ⇄ EP ⇄ E + P This example assumes the simplest case of a reaction with one substrate and one product. Such cases exist: for example, a mutase such as phosphoglucomutase ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mason Science College
Mason Science College was a university college in Birmingham, England, and a predecessor college of Birmingham University. Founded in 1875 by industrialist and philanthropist Sir Josiah Mason, the college was incorporated into the University of Birmingham in 1900. Two students of the college, Neville Chamberlain and Stanley Baldwin, later went on to become Prime Ministers of the UK. History The college was established by an English industrialist and philanthropist Sir Josiah Mason in 1875. The building of the college in Edmund Street, Birmingham was designed by Jethro Cossins and opened on 1 October 1880 and was marked by a speech by Thomas Henry Huxley. In the speech, Huxley considered the opening of the college as a victory for scientific cause and supported Mason's antagonistic views on the classics and theology. The college developed various liberal and vocational subjects, but forced out the artisans. The medical and scientific departments of Queen's College, Birmingh ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Horace Tabberer Brown
Horace Tabberer Brown FRS (20 July 1848 – 6 February 1925) was a British chemist. Early life He was born after the death of his biological father so his stepfather was the only father he knew. The stepfather was a banker and amateur naturalist which led to Brown's interest in science, which began around age 12. His younger half brother was Adrian John Brown. Career He started work at the Worthington Brewery in 1866. His focus was to solve practical brewing problems by employing and developing fundamental scientific principles. His research work considered barley germination, beer microbiology, water composition, oxygen and fermentation, beer haze formation, wort composition and beer analysis. A true polymath, he left his mark on virtually all areas of science as applied to brewing, in a career which lasted over 50 years. His earliest work concerned treatment of sewage and analyses of the Burton waters. Later he took up study of geology, being led to it by pressing requ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mason College
Mason Science College was a university college in Birmingham, England, and a predecessor college of Birmingham University. Founded in 1875 by industrialist and philanthropist Sir Josiah Mason, the college was incorporated into the University of Birmingham in 1900. Two students of the college, Neville Chamberlain and Stanley Baldwin, later went on to become Prime Ministers of the UK. History The college was established by an English industrialist and philanthropist Sir Josiah Mason in 1875. The building of the college in Edmund Street, Birmingham was designed by Jethro Cossins and opened on 1 October 1880 and was marked by a speech by Thomas Henry Huxley. In the speech, Huxley considered the opening of the college as a victory for scientific cause and supported Mason's antagonistic views on the classics and theology. The college developed various liberal and vocational subjects, but forced out the artisans. The medical and scientific departments of Queen's College, Birmingh ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Birmingham University
, mottoeng = Through efforts to heights , established = 1825 – Birmingham School of Medicine and Surgery1836 – Birmingham Royal School of Medicine and Surgery1843 – Queen's College1875 – Mason Science College1898 – Mason University College1900 – gained university status by royal charter , city = Birmingham , province = West Midlands , country = England, UK , coor = , campus = Urban, suburban , academic_staff = 5,495 (2020) , administrative_staff = , head_label = Visitor , head = The Rt Hon Penny Mordaunt MP , chancellor = Lord Bilimoria , vice_chancellor = Adam Tickell , type = Public , endowment = £134.5 million (2021) , budget = £774.1 million (2020–21) , students = () , undergrad = () , postgrad = () , affiliations = Universitas 21 Universities UK EUA ACUSutton 13 Russell Group , free_label = , free = , colours = The University , website = , logo = The University of Birmingham (informally Birmingham Universit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fermentation (biochemistry)
Fermentation is a metabolic process that produces chemical changes in organic substrates through the action of enzymes. In biochemistry, it is narrowly defined as the extraction of energy from carbohydrates in the absence of oxygen. In food production, it may more broadly refer to any process in which the activity of microorganisms brings about a desirable change to a foodstuff or beverage. The science of fermentation is known as zymology. In microorganisms, fermentation is the primary means of producing adenosine triphosphate (ATP) by the degradation of organic nutrients anaerobically. Humans have used fermentation to produce foodstuffs and beverages since the Neolithic age. For example, fermentation is used for preservation in a process that produces lactic acid found in such sour foods as pickled cucumbers, kombucha, kimchi, and yogurt, as well as for producing alcoholic beverages such as wine and beer. Fermentation also occurs within the gastrointestinal tracts of all an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sucrose
Sucrose, a disaccharide, is a sugar composed of glucose and fructose subunits. It is produced naturally in plants and is the main constituent of white sugar. It has the molecular formula . For human consumption, sucrose is extracted and refined from either sugarcane or sugar beet. Sugar mills – typically located in tropical regions near where sugarcane is grown – crush the cane and produce raw sugar which is shipped to other factories for refining into pure sucrose. Sugar beet factories are located in temperate climates where the beet is grown, and process the beets directly into refined sugar. The sugar-refining process involves washing the raw sugar crystals before dissolving them into a sugar syrup which is filtered and then passed over carbon to remove any residual colour. The sugar syrup is then concentrated by boiling under a vacuum and crystallized as the final purification process to produce crystals of pure sucrose that are clear, odorless, and sweet. Suga ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Athel Cornish-Bowden
Athel Cornish-Bowden (born 3 April 1943) is a British biochemist known for his numerous textbooks, particularly those on enzyme kinetics and his work on metabolic control analysis. Education and career Athel Cornish-Bowden worked on pepsin catalysis. This began a life long pursuit of work on enzyme catalysis and in later years work on the control of metabolism. More recently he has also turned his attention to work related to the origin and nature of life. He obtained his D.Phil. at Oxford with Jeremy R. Knowles, and carried out post-doctoral work with Daniel E. Koshland Jr. Research Cornish-Bowden has authored over 200 peer-reviewed papers and nine textbooks on topics related to enzyme kinetics, mathematics and historical perspectives in science. According to Google Scholar, the textbook, Fundamentals of enzyme kinetics, has been cited over 3000 times by secondary sources. Cornish-Bowden's research can be divided into three primary areas: Enzyme kinetics, metabolic control, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hermann Emil Fischer
Hermann Emil Louis Fischer (; 9 October 1852 – 15 July 1919) was a German chemist and 1902 recipient of the Nobel Prize in Chemistry. He discovered the Fischer esterification. He also developed the Fischer projection, a symbolic way of drawing asymmetric carbon atoms. He also hypothesized lock and key mechanism of enzyme action. He never used his first given name, and was known throughout his life simply as Emil Fischer. Early years and career Fischer was born in Euskirchen, near Cologne, the son of Laurenz Fischer, a businessman, and his wife Julie Poensgen. After graduating he wished to study natural sciences, but his father compelled him to work in the family business until determining that his son was unsuitable. Fischer then attended the University of Bonn in 1871, but switched to the University of Strasbourg in 1872. He earned his doctorate in 1874 under Adolf von Baeyer with his study of phthaleins, and was appointed to a position at the university. After eight ye ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1852 Births
Year 185 ( CLXXXV) was a common year starting on Friday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Lascivius and Atilius (or, less frequently, year 938 '' Ab urbe condita''). The denomination 185 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire * Nobles of Britain demand that Emperor Commodus rescind all power given to Tigidius Perennis, who is eventually executed. * Publius Helvius Pertinax is made governor of Britain and quells a mutiny of the British Roman legions who wanted him to become emperor. The disgruntled usurpers go on to attempt to assassinate the governor. * Tigidius Perennis, his family and many others are executed for conspiring against Commodus. * Commodus drains Rome's treasury to put on gladiatorial spectacles and confiscates property to su ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
