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Adipocere
Adipocere (), also known as corpse wax, grave wax or mortuary wax, is a wax-like organic substance formed by the anaerobic bacterial hydrolysis of fat in tissue, such as body fat in corpses. In its formation, putrefaction is replaced by a permanent firm cast of fatty tissues, internal organs, and the face. History Adipocere was first described by Sir Thomas Browne in his discourse ''Hydriotaphia, Urn Burial'' (1658): The chemical process of adipocere formation, saponification, came to be understood in the 17th century when microscopes became widely available. In 1825, physician and lecturer Augustus Granville is believed to have (somewhat unwittingly) made candles from the adipocere of a mummy and used them to light the public lecture he gave to report on the mummy's dissection. Granville apparently thought that the waxy material from which he made the candles had been used to preserve the mummy, rather than its being a product of the saponification of the mummified body. The b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lexico
Lexico was a dictionary website that provided a collection of English and Spanish dictionaries produced by Oxford University Press (OUP), the publishing house of the University of Oxford. While the dictionary content on Lexico came from OUP, this website was operated by Dictionary.com, whose eponymous website hosts dictionaries by other publishers such as Random House. The website was closed and redirected to Dictionary.com on 26 August 2022. Before the Lexico site was launched, the '' Oxford Dictionary of English'' and ''New Oxford American Dictionary'' were hosted by OUP's own website Oxford Dictionaries Online (ODO), later known as Oxford Living Dictionaries. The dictionaries' definitions have also appeared in Google definition search and the Dictionary application on macOS, among others, licensed through the Oxford Dictionaries API. History In the 2000s, OUP allowed access to content of the ''Compact Oxford English Dictionary of Current English'' on a website called AskOx ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pennsylvania
Pennsylvania (; ( Pennsylvania Dutch: )), officially the Commonwealth of Pennsylvania, is a state spanning the Mid-Atlantic, Northeastern, Appalachian, and Great Lakes regions of the United States. It borders Delaware to its southeast, Maryland to its south, West Virginia to its southwest, Ohio to its west, Lake Erie and the Canadian province of Ontario to its northwest, New York to its north, and the Delaware River and New Jersey to its east. Pennsylvania is the fifth-most populous state in the nation with over 13 million residents as of 2020. It is the 33rd-largest state by area and ranks ninth among all states in population density. The southeastern Delaware Valley metropolitan area comprises and surrounds Philadelphia, the state's largest and nation's sixth most populous city. Another 2.37 million reside in Greater Pittsburgh in the southwest, centered around Pittsburgh, the state's second-largest and Western Pennsylvania's largest city. The state's su ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Postmortem Interval
The post-mortem interval (PMI) is the time that has elapsed since an individual's death. When the time of death is not known, the interval may be estimated, and so an approximate time of death established. Postmortem interval estimations can range from hours, to days or even years depending on the type of evidence present. There are standard medical and scientific techniques supporting such an estimation. Examination of body and scene of death Changes to a body occurring after death ( post-mortem changes) include: * Algor mortis: body cooling; * Livor mortis: settling of blood in the lowest-placed parts of the body; * Rigor mortis: stiffening of limbs. Conditions at the scene of death affect the estimation of time of death. To ''algor mortis'', ''livor mortis'' and ''rigor mortis'', together with consideration of stomach contents, there needs to be some observation of environmental conditions at the death scene to accurately measure the PMI (Fig. 1). Factors that can effect t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Forensic Science
Forensic science, also known as criminalistics, is the application of science to criminal and civil laws, mainly—on the criminal side—during criminal investigation, as governed by the legal standards of admissible evidence and criminal procedure. Forensic science is a broad field that includes; DNA analysis, fingerprint analysis, blood stain pattern analysis, firearms examination and ballistics, tool mark analysis, serology, toxicology, hair and fiber analysis, entomology, questioned documents, anthropology, odontology, pathology, epidemiology, footwear and tire tread analysis, drug chemistry, paint and glass analysis, digital audio video and photo analysis. Forensic scientists collect, preserve, and analyze scientific evidence during the course of an investigation. While some forensic scientists travel to the scene of the crime to collect the evidence themselves, others occupy a laboratory role, performing analysis on objects brought to them by other individuals. Still ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Motor Cortex
The motor cortex is the region of the cerebral cortex believed to be involved in the planning, control, and execution of voluntary movements. The motor cortex is an area of the frontal lobe located in the posterior precentral gyrus immediately anterior to the central sulcus. Components of the motor cortex The motor cortex can be divided into three areas: 1. The primary motor cortex is the main contributor to generating neural impulses that pass down to the spinal cord and control the execution of movement. However, some of the other motor areas in the brain also play a role in this function. It is located on the anterior paracentral lobule on the medial surface. 2. The premotor cortex is responsible for some aspects of motor control, possibly including the preparation for movement, the sensory guidance of movement, the spatial guidance of reaching, or the direct control of some movements with an emphasis on control of proximal and trunk muscles of the body. Located anterior ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nissl Body
Nissl bodies (also called Nissl granules, Nissl substance or tigroid substance) are discrete granular structures in neurons that consist of rough endoplasmic reticulum, a collection of parallel, membrane-bound cisternae studded with ribosomes on the cystosolic surface of the membranes. Nissl bodies were named after Franz Nissl, a German neuropathologist who invented the staining method bearing his name ( Nissl staining). The term "Nissl bodies" generally refers to discrete clumps of rough endoplasmic reticulum in nerve cells. Masses of rough endoplasmic reticulum also occur in some non-neuronal cells, where they are referred to as ergastoplasm, basophilic bodies, or chromophilic substance. While these organelles differ in some ways from Nissl bodies in neurons, large amounts of rough endoplasmic reticulum are generally linked to the copious production of proteins. Staining "Nissl stains" refers to various basic dyes that selectively label negatively charged molecules such as DNA ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gyri
In neuroanatomy, a gyrus (pl. gyri) is a ridge on the cerebral cortex. It is generally surrounded by one or more sulci (depressions or furrows; sg. ''sulcus''). Gyri and sulci create the folded appearance of the brain in humans and other mammals. Structure The gyri are part of a system of folds and ridges that create a larger surface area for the human brain and other mammalian brains. Because the brain is confined to the skull, brain size is limited. Ridges and depressions create folds allowing a larger cortical surface area, and greater cognitive function, to exist in the confines of a smaller cranium. Development The human brain undergoes gyrification during fetal and neonatal development. In embryonic development, all mammalian brains begin as smooth structures derived from the neural tube. A cerebral cortex without surface convolutions is lissencephalic, meaning 'smooth-brained'. As development continues, gyri and sulci begin to take shape on the fetal brain, with ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sulcus (neuroanatomy)
In neuroanatomy, a sulcus (Latin: "furrow", pl. ''sulci'') is a depression or groove in the cerebral cortex. It surrounds a gyrus (pl. gyri), creating the characteristic folded appearance of the brain in humans and other mammals. The larger sulci are usually called fissures. Structure Sulci, the grooves, and gyri, the folds or ridges, make up the folded surface of the cerebral cortex. Larger or deeper sulci are termed fissures, and in many cases the two terms are interchangeable. The folded cortex creates a larger surface area for the brain in humans and other mammals. When looking at the human brain, two-thirds of the surface are hidden in the grooves. The sulci and fissures are both grooves in the cortex, but they are differentiated by size. A sulcus is a shallower groove that surrounds a gyrus. A fissure is a large furrow that divides the brain into lobes and also into the two hemispheres as the longitudinal fissure. Importance of expanded surface area As the surfac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Embalmed
Embalming is the art and science of preserving human remains by treating them (in its modern form with chemicals) to forestall decomposition. This is usually done to make the deceased suitable for public or private viewing as part of the funeral ceremony or keep them preserved for medical purposes in an anatomical laboratory. The three goals of embalming are sanitization, presentation, and preservation, with restoration being an important additional factor in some instances. Performed successfully, embalming can help preserve the body for a duration of many years. Embalming has a very long and cross-cultural history, with many cultures giving the embalming processes a greater religious meaning. Animal remains can also be embalmed by similar methods, but embalming is distinct from taxidermy. Embalming preserves the body intact, whereas taxidermy is the recreation of an animal's form often using only the creature's skin mounted on an anatomical form. History It is important to no ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brown Adipose Tissue
Brown adipose tissue (BAT) or brown fat makes up the adipose organ together with white adipose tissue (or white fat). Brown adipose tissue is found in almost all mammals. Classification of brown fat refers to two distinct cell populations with similar functions. The first shares a common embryological origin with muscle cells, found in larger "classic" deposits. The second develops from white adipocytes that are stimulated by the sympathetic nervous system. These adipocytes are found interspersed in white adipose tissue and are also named 'beige' or 'brite' (for "brown in white"). Brown adipose tissue is especially abundant in newborns and in hibernating mammals. It is also present and metabolically active in adult humans, but its prevalence decreases as humans age. Its primary function is thermoregulation. In addition to heat produced by shivering muscle, brown adipose tissue produces heat by non-shivering thermogenesis. The therapeutic targeting of brown fat for the treatment o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
White Adipose Tissue
White adipose tissue or white fat is one of the two types of adipose tissue found in mammals. The other kind is brown adipose tissue. White adipose tissue is composed of monolocular adipocytes. In humans, the healthy amount of white adipose tissue varies with age, but composes between 6-25% of body weight in adult men and 14-35% in adult women. Its cells contain a single large fat droplet, which forces the nucleus to be squeezed into a thin rim at the periphery. They have receptors for insulin, sex hormones, norepinephrine, and glucocorticoids. White adipose tissue is used for energy storage. Upon release of insulin from the pancreas, white adipose cells' insulin receptors cause a dephosphorylation cascade that leads to the inactivation of hormone-sensitive lipase. It was previously thought that upon release of glucagon from the pancreas, glucagon receptors cause a phosphorylation cascade that activates hormone-sensitive lipase, causing the breakdown of the stored fat to fatt ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fatty Acid
In chemistry, particularly in biochemistry, a fatty acid is a carboxylic acid with an aliphatic chain, which is either saturated or unsaturated. Most naturally occurring fatty acids have an unbranched chain of an even number of carbon atoms, from 4 to 28. Fatty acids are a major component of the lipids (up to 70% by weight) in some species such as microalgae but in some other organisms are not found in their standalone form, but instead exist as three main classes of esters: triglycerides, phospholipids, and cholesteryl esters. In any of these forms, fatty acids are both important dietary sources of fuel for animals and important structural components for cells. History The concept of fatty acid (''acide gras'') was introduced in 1813 by Michel Eugène Chevreul, though he initially used some variant terms: ''graisse acide'' and ''acide huileux'' ("acid fat" and "oily acid"). Types of fatty acids Fatty acids are classified in many ways: by length, by saturation vs unsaturati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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