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Aaron Ciechanover
Aaron Ciechanover ( ; he, אהרן צ'חנובר; born October 1, 1947) is an Israeli biologist who won the Nobel Prize in Chemistry for characterizing the method that cells use to degrade and recycle proteins using ubiquitin. Biography Early life Ciechanover was born in Haifa, British Mandate of Palestine on 1 October 1947. He is the son of Bluma (Lubashevsky), a teacher of English, and Yitzhak Ciechanover, an office worker. His mother and father supported the Zionist movement and immigrated to Israel from Poland in the 1920s. Education He earned a master's degree in science in 1971 and graduated from Hadassah Medical School in Jerusalem in 1974. He received his doctorate in biochemistry in 1981 from the Technion – Israel Institute of Technology in Haifa before conducting postdoctoral research in the laboratory of Harvey Lodish at the Whitehead Institute at MIT from 1981 to 1984. Recent Ciechanover is currently a Technion Distinguished Research Professor in the Rut ...
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Haifa
Haifa ( he, חֵיפָה ' ; ar, حَيْفَا ') is the third-largest city in Israel—after Jerusalem and Tel Aviv—with a population of in . The city of Haifa forms part of the Haifa metropolitan area, the third-most populous metropolitan area in Israel. It is home to the Baháʼí Faith's Baháʼí World Centre, and is a UNESCO World Heritage Site and a destination for Baháʼí pilgrimage. Built on the slopes of Mount Carmel, the settlement has a history spanning more than 3,000 years. The earliest known settlement in the vicinity was Tell Abu Hawam, a small port city established in the Late Bronze Age (14th century BCE). Encyclopedia Judaica, ''Haifa'', Keter Publishing, Jerusalem, 1972, vol. 7, pp. 1134–1139 In the 3rd century CE, Haifa was known as a dye-making center. Over the millennia, the Haifa area has changed hands: being conquered and ruled by the Canaanites, Israelites, Phoenicians, Assyrians, Babylonians, Persians, Hasmoneans, Romans, Byzantines, ...
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United States National Academy Of Sciences
The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the National Academy of Medicine (NAM). As a national academy, new members of the organization are elected annually by current members, based on their distinguished and continuing achievements in original research. Election to the National Academy is one of the highest honors in the scientific field. Members of the National Academy of Sciences serve '' pro bono'' as "advisers to the nation" on science, engineering, and medicine. The group holds a congressional charter under Title 36 of the United States Code. Founded in 1863 as a result of an Act of Congress that was approved by Abraham Lincoln, the NAS is charged with "providing independent, objective advice to the nation on matters related to science and technology. ... to provide scie ...
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Nobel Prize
The Nobel Prizes ( ; sv, Nobelpriset ; no, Nobelprisen ) are five separate prizes that, according to Alfred Nobel's will of 1895, are awarded to "those who, during the preceding year, have conferred the greatest benefit to humankind." Alfred Nobel was a Swedish chemist, engineer, and industrialist most famously known for the invention of dynamite. He died in 1896. In his will, he bequeathed all of his "remaining realisable assets" to be used to establish five prizes which became known as "Nobel Prizes." Nobel Prizes were first awarded in 1901. Nobel Prizes are awarded in the fields of Physics, Chemistry, Physiology or Medicine, Literature, and Peace (Nobel characterized the Peace Prize as "to the person who has done the most or best to advance fellowship among nations, the abolition or reduction of standing armies, and the establishment and promotion of peace congresses"). In 1968, Sveriges Riksbank (Sweden's central bank) funded the establishment of the Prize in Economi ...
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Israel Prize
The Israel Prize ( he, פרס ישראל; ''pras israél'') is an award bestowed by the State of Israel, and regarded as the state's highest cultural honor. History The Israel Prize is awarded annually, on Israeli Independence Day, in a state ceremony in Jerusalem, in the presence of the President, the Prime Minister, the Speaker of the Knesset (Israel's legislature), and the Supreme Court President. The prize was established in 1953 at the initiative of the Minister of Education Ben-Zion Dinor, who himself went on to win the prize in 1958 and 1973. Awarding the prize The prize is awarded in the following four areas, with the precise subfields changing from year to year in a cycle of 4 to 7 years, except for the last area, which is awarded annually: * the humanities, social sciences, and Jewish studies * life and exact sciences * culture, arts, communication and sports * lifetime achievement and exceptional contribution to the nation (since 1972) The recipients of the prize are ...
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Albert Lasker Award For Basic Medical Research
The Albert Lasker Award for Basic Medical Research is one of the prizes awarded by the Lasker Foundation for a fundamental discovery that opens up a new area of biomedical science. The award frequently precedes a Nobel Prize in Medicine; almost 50% of the winners have gone on to win one. List of Albert Lasker Award for Basic Medical Research recipients {, , Valign="top", {, class="wikitable" ! Year !! Recipient , - , Rowspan="3", 2022 , , Richard O. Hynes , - , , Erkki Ruoslahti , - , , Timothy A. Springer , - , Rowspan="3", 2021 , , Karl Deisseroth , - , , Peter Hegemann , - , , Dieter Oesterhelt , - , Rowspan="1", 2020 , , not awarded   , - , Rowspan="2", 2019 , , Max Dale Cooper , - , , Jacques Miller , - , Rowspan="2", 2018 , , C. David Allis , - , , Michael Grunstein , - , Rowspan="1", 2017 , , Michael N. Hall , - , Rowspan="3", 2016 , , William Kaelin, Jr. , - , , Peter J. Ratcliffe , - , , Gregg L. Semenza , - , R ...
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Protalix BioTherapeutics
Protalix BioTherapeutics is an Israeli pharmaceutical company that manufactures a plant-based enzyme, taliglucerase alfa, which has received U.S. Food and Drug Administration approval for the treatment of Gaucher disease. Corporate history Protalix BioTherapeutics was established in 1993. It was founded by Yoseph Shaaltiel, who received his Ph.D. in Plant Biochemistry from the Weizmann Institute in Israel and served in the Biology Department of the Israel Defense Forces' Biological and Chemical Center. One of the earliest and largest investors in the company was Phillip Frost. Protalix has two Nobel Prize winners (Chemistry) in its Scientific Advisory Board, Roger Kornberg Ph.D and Prof. MD. Aaron Ciechanover. In its early days Protalix operated out of a warehouse in the town of Qiryat Shemona in northern Israel. On July 19, 2005, Protalix Biotherapeutics announced the closing of a $5.3 million private placement of its series C preferred stock. Protalix entered into a partne ...
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StemRad
StemRad is an Israeli-American start-up company that develops and manufactures personal protective equipment (PPE) against ionizing radiation. Its first product was the 360 Gamma, a device that protects the user's pelvic bone marrow from gamma radiation. StemRad has also developed the StemRad MD, a protective suit designed to provide whole-body radiation protection to physicians, and the AstroRad vest for radiation protection in space, which is currently being tested on the International Space Station and is one of the primary payloads onboard NASA's Artemis 1 lunar mission. History StemRad was founded in December 2011 by Oren Milstein and Daniel Levitt. They were inspired to create the company by the Chernobyl disaster where many of the firemen and engineers, who were first on the scene, died from high doses of gamma radiation in an illness known as Acute Radiation Syndrome (ARS), also known as radiation sickness. This idea was fueled by a sense of urgency due to the growing nu ...
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BioLineRx
BioLineRx (), or BioLine, is a publicly traded drug development company. Headquartered in Israel, its shares are traded on the NASDAQ Capital Market and on the Tel Aviv Stock Exchange. Corporate history The firm was established in 2003 as a joint venture of Teva Pharmaceutical Industries, Teva, Hadasit Bio-Holdings, the Jerusalem Development Authority, Yehuda Zisapel, and other investors. It executed an initial public offering on the Tel Aviv Stock Exchange in February 2007, raising 211 million New Israeli shekel, NIS ($50 million) – the TASE's largest biotech IPO until that time. In July 2011 BioLine's American depositary receipt, ADRs began trading on the NASDAQ Capital Market. In January 2012, the firm announced a deal with Genoscience, a French pharmaceutical company to jointly develop and market the BL-8020 compound, as a treatment for Hepatitis C. At the end of 2014, Novartis acquired a 12.8% Equity (finance), stake in the company as a strategic move to gain access to Is ...
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Rosetta Genomics
Rosetta Genomics Ltd. was a molecular diagnostics company with offices in Israel and the United States that uses micro-ribonucleic acid (microRNA) biomarkers to develop diagnostic tests designed to differentiate between various types of cancer. The company expects the first three tests based on its technology to be submitted for regulatory approval in 2008."Columbia University Medical Center and Rosetta Genomics Announce Columbia University's Submission of the First Cancer Diagnostic Test Based on Rosetta Genomics Proprietary MicroRNA Technology for Approval to the New York State Department of Health Clinical Laboratory Evaluation Program," Forbes.com, April 3, 2008 The diagnostic tests will differentiate between squamous and non-squamous non-small cell lung cancer (NSCLC); differentiate between adenocarcinoma and peritoneal mesothelioma;"Rosetta Genomics Ltd. Completes Prevalidation Phase for First Diagnostic Production." ''Reuters'', October 30, 2007. and seek to identify the o ...
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History Of The Technion – Israel Institute Of Technology
The Technion – Israel Institute of Technology is a leading technical university in Haifa, Israel, with a history dating back to the early 20th century. Overview The extent to which technology determines history and the creation and destiny of nations is a question of historical scholarship, with the Technion – Israel Institute of Technology cited as a striking example. Initiated with the help of increasing Jewish unity made possible by the new communication technologies of the Second Industrial Revolution, the Technion was born 36 years before Israel declared independence. In that time it educated the engineers and brought the expertise to literally lay the infrastructure for a modern state. This included the fundamental infrastructure of electricity, water supplies and roads. Throughout the century – since the laying of the first cornerstone in 1912 – Technion has had a historic task in anticipating future needs in order to ensure the survival and growth of the State o ...
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Science
Science is a systematic endeavor that builds and organizes knowledge in the form of testable explanations and predictions about the universe. Science may be as old as the human species, and some of the earliest archeological evidence for scientific reasoning is tens of thousands of years old. The earliest written records in the history of science come from Ancient Egypt and Mesopotamia in around 3000 to 1200 BCE. Their contributions to mathematics, astronomy, and medicine entered and shaped Greek natural philosophy of classical antiquity, whereby formal attempts were made to provide explanations of events in the physical world based on natural causes. After the fall of the Western Roman Empire, knowledge of Greek conceptions of the world deteriorated in Western Europe during the early centuries (400 to 1000 CE) of the Middle Ages, but was preserved in the Muslim world during the Islamic Golden Age and later by the efforts of Byzantine Greek scholars who brought Greek ...
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