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BioLineRx
BioLineRx (), or BioLine, is a publicly traded drug development company. Headquartered in Israel, its shares are traded on the NASDAQ Capital Market and on the Tel Aviv Stock Exchange. Corporate history The firm was established in 2003 as a joint venture of Teva Pharmaceutical Industries, Teva, Hadasit Bio-Holdings, the Jerusalem Development Authority, Yehuda Zisapel, and other investors. It executed an initial public offering on the Tel Aviv Stock Exchange in February 2007, raising 211 million New Israeli shekel, NIS ($50 million) – the TASE's largest biotech IPO until that time. In July 2011 BioLine's American depositary receipt, ADRs began trading on the NASDAQ Capital Market. In January 2012, the firm announced a deal with Genoscience, a French pharmaceutical company to jointly develop and market the BL-8020 compound, as a treatment for Hepatitis C. At the end of 2014, Novartis acquired a 12.8% Equity (finance), stake in the company as a strategic move to gain access to Is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jerusalem Development Authority
The Jerusalem Development Authority (), or JDA, is a joint agency of the Israeli government and the Jerusalem Municipality that works to promote and develop the economy of the city of Jerusalem. The Authority was founded by Uziel Wexler and was established as a statutory corporation under the Jerusalem Development Authority Law 1988. Teddy Kollek was one of the key figures behind its establishment. Overview According to Ira Sharkansky, the mandate of the Jerusalem Development Authority involves "encouraging, planning, and initiating activities concerned with the economic development of Jerusalem and coordinating Jerusalem's economic development among government ministries, municipal officials, and other bodies." Established as a statutory corporation through the Jerusalem Development Authority Law 1988, by 1992 the Authority had invested over $1 billion in construction projects and initiatives relating to science and technology in Jerusalem. The Authority was among the factors i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
BL-1020
BL-1020 (perphenazine 4-aminobutanoate) is an investigational orally-active antipsychotic for the possible treatment of schizophrenia. The chemical is an ester of GABA and perphenazine; pharmacologically it acts as a D2 antagonist and GABA agonist. It has shown pro-cognitive effects in the trials. In March 2013, it went into the II/III trial phase. It has been introduced by BioLineRx BioLineRx (), or BioLine, is a publicly traded drug development company. Headquartered in Israel, its shares are traded on the NASDAQ Capital Market and on the Tel Aviv Stock Exchange. Corporate history The firm was established in 2003 as a jo ..., a biopharmaceutical development company. References 5-HT2A antagonists Antipsychotics D2 antagonists GABA receptor agonists Chloroarenes Piperazines {{nervous-system-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Public Company
A public company is a company whose ownership is organized via shares of stock which are intended to be freely traded on a stock exchange or in over-the-counter markets. A public (publicly traded) company can be listed on a stock exchange (listed company), which facilitates the trade of shares, or not (unlisted public company). In some jurisdictions, public companies over a certain size must be listed on an exchange. In most cases, public companies are ''private'' enterprises in the ''private'' sector, and "public" emphasizes their reporting and trading on the public markets. Public companies are formed within the legal systems of particular states, and therefore have associations and formal designations which are distinct and separate in the polity in which they reside. In the United States, for example, a public company is usually a type of corporation (though a corporation need not be a public company), in the United Kingdom it is usually a public limited company (plc), i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
New Israeli Shekel
The new Israeli shekel ( he, שֶׁקֶל חָדָשׁ '; ar, شيكل جديد ; sign: ₪; ISO code: ILS; abbreviation: NIS), also known as simply the Israeli shekel ( he, שקל ישראלי, ar, شيكل إسرائيلي), is the currency of Israel and is also used as a legal tender in the Palestinian territories of the West Bank and the Gaza Strip. The new shekel is divided into 100 agorot. The new shekel has been in use since 1 January 1986, when it replaced the hyperinflated old shekel at a ratio of 1000:1. The currency sign for the new shekel is a combination of the first Hebrew letters of the words ''shekel'' () and ''ẖadash'' () (new). When the shekel sign is unavailable the abbreviation ''NIS'' ( and ) is used. History The origin of the name "shekel" () is from the ancient Biblical currency by the same name. An early Biblical reference is Abraham being reported to pay "four hundred shekels of silver" to Ephron the Hittite for the Cave of the Patriarc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neuropathic Pain
Neuropathic pain is pain caused by damage or disease affecting the somatosensory system. Neuropathic pain may be associated with abnormal sensations called dysesthesia or pain from normally non-painful stimuli (allodynia). It may have continuous and/or episodic (paroxysmal) components. The latter resemble stabbings or electric shocks. Common qualities include burning or coldness, "pins and needles" sensations, numbness and itching. Up to 7%-8% of the European population is affected, and in 5% of persons it may be severe. Neuropathic pain may result from disorders of the peripheral nervous system or the central nervous system (brain and spinal cord). Thus, neuropathic pain may be divided into peripheral neuropathic pain, central neuropathic pain, or mixed (peripheral and central) neuropathic pain. Neuropathic pain may occur in isolation or in combination with other forms of pain. Medical treatments focus on identifying the underlying cause and relieving pain. In cases of neuropathy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Product Pipeline
A product pipeline is a series of products, either in a state of development, preparation, or production, developed and sold by a company, and ideally in different stages of their life cycle. At any point in a company's life, the goal is to have some products in the growth stage, which is the key stage for establishing a product's position in a market, increasing sales, and improving profit margins; and the maturity stage, which is key to maintaining market share. This term is particularly common in the pharmaceutical industry, where products can spend a decade or more in the pipeline. General Features * Time constraints (because of first move advantage, patent expiration etc.) * An element of risk and reward (weighing up potential profit against the cost of development) * The use of raw materials and resources (to create the product) * Often both capital and time intensive (High cost and lengthy development process) * Tasks along the development process with a success and failu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Globes (newspaper)
''Globes'' ( he, גלובס) is a Hebrew-language daily evening financial newspaper in Israel. Globes was founded in the early 1980s and published in Tel Aviv, Israel. It deals with economic issues and news from the Israeli and international business worlds. The paper is printed on salmon-colored paper, inspired by the British ''Financial Times''. ''Globes'' was one of the first Israeli dailies to publish its contents on the World Wide Web, dating back to April 1995. Its web version publishes in Hebrew and English. According to TGI 2022 media survey, ''Globes'' market share is 4.1% among Israeli financial newspapers. Its main competitors as Israeli financial newspapers in printed media are ''TheMarker'', of the ''Haaretz'' group, and ''Calcalist'', published by the ''Yedioth Ahronoth'' Group. History The daily paper founded by Haim Bar-On, the publisher of the newspaper, on the basis of a small, Haifa-based financial newspaper, in partnership with businessman Eliezer Fishman. F ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pre-clinical Development
In drug development, preclinical development, also termed preclinical studies or nonclinical studies, is a stage of research that begins before clinical trials (testing in humans) and during which important feasibility, iterative testing and drug safety data are collected, typically in laboratory animals. The main goals of preclinical studies are to determine a starting, safe dose for first-in-human study and assess potential toxicity of the product, which typically include new medical devices, prescription drugs, and diagnostics. Companies use stylized statistics to illustrate the risks in preclinical research, such as that on average, only one in every 5,000 compounds that enters drug discovery to the stage of preclinical development becomes an approved drug. Types of preclinical research Each class of product may undergo different types of preclinical research. For instance, drugs may undergo pharmacodynamics (what the drug does to the body) (PD), pharmacokinetics (wh ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bloomberg Business
''Bloomberg Businessweek'', previously known as ''BusinessWeek'', is an American weekly business magazine published fifty times a year. Since 2009, the magazine is owned by New York City-based Bloomberg L.P. The magazine debuted in New York City in September 1929. Bloomberg Businessweek business magazines are located in the Bloomberg Tower, 731 Lexington Avenue, Manhattan in New York City and market magazines are located in the Citigroup Center, 153 East 53rd Street between Lexington and Third Avenue, Manhattan in New York City. History ''Businessweek'' was first published based in New York City in September 1929, weeks before the stock market crash of 1929. The magazine provided information and opinions on what was happening in the business world at the time. Early sections of the magazine included marketing, labor, finance, management and Washington Outlook, which made ''Businessweek'' one of the first publications to cover national political issues that directly impacted the b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tel Aviv University
Tel Aviv University (TAU) ( he, אוּנִיבֶרְסִיטַת תֵּל אָבִיב, ''Universitat Tel Aviv'') is a public research university in Tel Aviv, Israel. With over 30,000 students, it is the largest university in the country. Located in northwest Tel Aviv, the university is the center of teaching and research of the city, comprising 9 faculties, 17 teaching hospitals, 18 performing arts centers, 27 schools, 106 departments, 340 research centers, and 400 laboratories. Tel Aviv University originated in 1956 when three education units merged to form the university. The original 170-acre campus was expanded and now makes up 220 acres (89 hectares) in Tel Aviv's Ramat Aviv neighborhood. History TAU's origins date back to 1956, when three research institutes: the Tel Aviv School of Law and Economics (established in 1935), the Institute of Natural Sciences (established in 1931), and the Academic Institute of Jewish Studies (established in 1954) – joined to form Tel Aviv ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kinneret Savitsky
Kinneret is the English transliteration for Kineret, the Hebrew name of the Sea of Galilee, the largest freshwater lake in Israel. Other meanings of Kinneret and Kineret include: Places * Camp Kinneret, a summer camp of Canadian Young Judaea * Kinneret (archaeological site), biblical city which gave the Sea of Galilee its Hebrew name; now Tell el-'Oreimeh or Tel Kinrot on the northwestern coast of the lake * Kinneret College, college south of the Sea of Galilee * Kinneret Farm, experimental training farm (1908-1949), now museum * Kinneret Subdistrict, Israel * Kvutzat Kinneret, kibbutz southwest of the Sea of Galilee * Moshavat Kinneret, village (''moshava'') southwest of the Sea of Galilee People * Kineret (singer), an Orthodox Jewish recording artist * Kinneret Shiryon (born 1955), Reform rabbi, the first female rabbi in Israel Other * Kineret (medication), brand name of anakinra; no direct relation to the lake * ''Kinneret'', Israeli song based on Rachel Bluwstein's poem "Per ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Downstate Medical Center
SUNY Downstate Health Sciences University (Downstate) is a public medical school and hospital in Brooklyn, New York. It is the southernmost member of the State University of New York (SUNY) system and the only academic medical center for health education, research, and patient care serving Brooklyn's 2.5 million residents. As of Fall 2018, it had a total student body of 1,846 and approximately 8,000 faculty and staff. Downstate Medical Center comprises a College of Medicine, Colleges of Nursing and Health Related Professions, Schools of Graduate Studies and Public Health, and University Hospital of Brooklyn. It also includes a major research complex and biotechnology facilities. SUNY Downstate ranks eighth nationally in the number of alumni who are on the faculty of American medical schools. More physicians practicing in New York City graduated from Downstate than from any other medical school. With 1,040 residents (young physicians in training), Downstate's residency progra ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
