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ATC Code C04
C04A Peripheral vasodilators C04AA 2-amino-1-phenylethanol derivatives :C04AA01 Isoxsuprine :C04AA02 Buphenine :C04AA31 Bamethan C04AB Imidazoline derivatives :C04AB01 Phentolamine :C04AB02 Tolazoline C04AC Nicotinic acid and derivatives :C04AC01 Nicotinic acid :C04AC02 Nicotinyl alcohol (pyridylcarbinol) :C04AC03 Inositol nicotinate :C04AC07 Ciclonicate C04AD Purine derivatives :C04AD01 Pentifylline :C04AD02 Xantinol nicotinate :C04AD03 Pentoxifylline :C04AD04 Etofylline nicotinate :QC04AD90 Propentofylline C04AE Ergot alkaloids :C04AE01 Ergoloid mesylates :C04AE02 Nicergoline :C04AE04 Dihydroergocristine :C04AE51 Ergoloid mesylates, combinations :C04AE54 Dihydroergocristine, combinations C04AF Enzymes :C04AF01 Kallidinogenase C04AX Other peripheral vasodilators :C04AX01 Cyclandelate :C04AX02 Phenoxybenzamine :C04AX07 Vincamine :C04AX10 Moxisylyte :C04AX11 Bencyclane :C04AX17 Vinburnine :C04AX19 Sulcotidil :C04AX20 Buflomedil :C04AX21 Naftidrofuryl :C04AX2 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vasodilator
Vasodilation is the widening of blood vessels. It results from relaxation of smooth muscle cells within the vessel walls, in particular in the large veins, large arteries, and smaller arterioles. The process is the opposite of vasoconstriction, which is the narrowing of blood vessels. When blood vessels dilate, the flow of blood is increased due to a decrease in vascular resistance and increase in cardiac output. Therefore, dilation of arterial blood vessels (mainly the arterioles) decreases blood pressure. The response may be intrinsic (due to local processes in the surrounding tissue) or extrinsic (due to hormones or the nervous system). In addition, the response may be localized to a specific organ (depending on the metabolic needs of a particular tissue, as during strenuous exercise), or it may be systemic (seen throughout the entire systemic circulation). Endogenous substances and drugs that cause vasodilation are termed vasodilators. Such vasoactivity is necessary for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Etofylline Nicotinate
Etofylline nicotinate is a vasodilator Vasodilation is the widening of blood vessels. It results from relaxation of smooth muscle cells within the vessel walls, in particular in the large veins, large arteries, and smaller arterioles. The process is the opposite of vasoconstriction, .... References Nicotinate esters Xanthines Vasodilators {{cardiovascular-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vinburnine
Vinburnine (or eburnamonine, ''Vincamone'') is a vasodilator Vasodilation is the widening of blood vessels. It results from relaxation of smooth muscle cells within the vessel walls, in particular in the large veins, large arteries, and smaller arterioles. The process is the opposite of vasoconstriction, .... Vincamone is a vinca alkaloid and a metabolite of vincamine. References Vinca alkaloids Vasodilators Lactams Nitrogen heterocycles Heterocyclic compounds with 5 rings {{cardiovascular-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bencyclane
Bencyclane is an antispasmodic, vasodilator, and platelet aggregation inhibitor. Synthesis Grignard addition of benzylmagnesiumbromide to suberone would give 1-benzylcycloheptanol 006-73-9(1'). Williamson ether synthesis with 3-dimethylaminopropylchloride 09-54-6(2) completed the synthesis of bencyclane (3). See also *Clofenciclan Clofenciclan (Chlorphencyclan; Tonquil, Vesitan) is a dopamine-releasing agent developed by Boehringer & Soehne in the 1950s. It proved unpopular as a treatment because of its pronounced stimulant activity. See also * Arylcyclohexylamine Ar ... References Calcium channel blockers Ethers Dimethylamino compounds {{Amine-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Moxisylyte
Moxisylyte, also known as thymoxamine, is a drug used in urology for the treatment of erectile dysfunction. It is an α1-adrenergic antagonist. In the United Kingdom, Moxisylte is marketed as Opilon (Archimedes Pharma UK Ltd) and is used for the short-term treatment of primary Raynaud's syndrome Raynaud syndrome, also known as Raynaud's phenomenon, eponymously named after the physician Auguste Gabriel Maurice Raynaud, who first described it in his doctoral thesis in 1862, is a medical condition in which the spasm of small arteries cau .... This is a condition where the fingers and toes become discoloured and is triggered by responses to cold, or emotional distress. Opilon tablets help by improving blood circulation to the extremities. References Acetate esters Alpha-1 blockers Hepatotoxins Phenol ethers {{Genito-urinary-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vincamine
Vincamine is a monoterpenoid indole alkaloid found in the leaves of ''Vinca minor'' (lesser periwinkle), comprising about 25-65% of its indole alkaloids by weight. It can also be synthesized from related alkaloids. Uses Vincamine is sold in Europe as a prescription medicine for the treatment of primary degenerative and vascular dementia. In the United States, it is permitted to be sold as a dietary supplement when labeled for use in adults for six months or less. Most common preparations are in the sustained release tablet forms. Chemistry Synthesis Tabersonine can be used for semi-synthesis of vincamine. Derivatives Vinpocetine is a synthetic derivative of vincamine used for cerebrovascular diseases and as dietary supplement. Vincamine derivatives have been also studied as anti addictive and antidiabetic agents. Research It may have nootropic effects. It has been investigated as novel anticancer drug. See also *Apparicine *Conophylline Conophylline is a autophagy induci ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phenoxybenzamine
Phenoxybenzamine (marketed under the trade names Dibenzyline and Dibenyline) is a non-selective, irreversible alpha blocker. Uses It is used in the treatment of hypertension, and specifically that caused by pheochromocytoma. It has a slower onset and a longer-lasting effect compared with other alpha blockers. It was also the first alpha blocker to be used for treatment of benign prostatic hyperplasia, although it is currently seldom used for that indication due to unfavourable side effects. It has been used in the treatment of hypoplastic left heart syndrome. It is also used in complex regional pain syndrome (CRPS) type 1 due to its antiadrenergic effects. It has shown to be beneficial if used in the first 3 months of the CRPS diagnosis. Investigational Phenoxybenzamine has long been known to block ejaculation without affecting semen quality or ability to achieve orgasm, which could make it an effective male contraceptive. This effect is completely reversible, and is belie ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cyclandelate
Cyclandelate is a vasodilator used in the treatment of claudication, arteriosclerosis and Raynaud's disease. It is also used to treat nighttime leg cramps, and has been investigated for its effect against migraine Migraine (, ) is a common neurological disorder characterized by recurrent headaches. Typically, the associated headache affects one side of the head, is pulsating in nature, may be moderate to severe in intensity, and could last from a few hou .... It is orally administered. References Acetate esters Secondary alcohols 3,3,5-Trimethylcyclohexyl esters {{cardiovascular-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kallidinogenase
Urinary kallikrein may refer to: * Plasma kallikrein Plasma kallikrein (, ''serum kallikrein'', ''kininogenin'', ''kallikrein I'', ''kallikrein II'', ''kininogenase'', ''kallikrein'', ''callicrein'', ''glumorin'', ''padreatin'', ''padutin'', ''kallidinogenase'', ''bradykininogenase'', ''panceatic ka ..., an enzyme * Renal tissue kallikrein, an enzyme {{Short pages monitor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. Almost all metabolic processes in the cell need enzyme catalysis in order to occur at rates fast enough to sustain life. Metabolic pathways depend upon enzymes to catalyze individual steps. The study of enzymes is called ''enzymology'' and the field of pseudoenzyme analysis recognizes that during evolution, some enzymes have lost the ability to carry out biological catalysis, which is often reflected in their amino acid sequences and unusual 'pseudocatalytic' properties. Enzymes are known to catalyze more than 5,000 biochemical reaction types. Other biocatalysts are catalytic RNA molecules, called ribozymes. Enzymes' specificity comes from their unique three-dimensional structures. Like all catalysts, enzymes increase the reaction ra ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dihydroergocristine
Dihydroergocristine is an ergot alkaloid. Alongside dihydroergocornine and dihydroergocryptine Dihydroergocryptine (DHEC), sold under the brand names Almirid and Cripar among others, is a dopamine agonist of the ergoline group that is used as an antiparkinson agent in the treatment of Parkinson's disease. It is taken by mouth. Medical us ..., it is one of the components of ergoloid mesylates. References Ergot alkaloids Isopropyl compounds Lactams Lysergamides Oxazolopyrrolopyrazines Vasodilators {{Cardiovascular-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nicergoline
Nicergoline, sold under the brand name Sermion among others, is an ergot derivative used to treat senile dementia and other disorders with vascular origins. Internationally it has been used for frontotemporal dementia as well as early onset in Lewy body dementia and Parkinson's dementia. It decreases vascular resistance and increases arterial blood flow in the brain, improving the utilization of oxygen and glucose by brain cells. It has similar vasoactive properties in other areas of the body, particularly the lungs. Unlike many other ergolines, such as ergotamine, nicergoline is not associated with cardiac fibrosis. It is used for vascular disorders such as cerebral thrombosis and atherosclerosis, arterial blockages in the limbs, Raynaud's disease, vascular migraines, and retinopathy. Nicergoline has been registered in over fifty countries and has been used for more than three decades for the treatment of cognitive, affective, and behavioral disorders of older people. Medical ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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