C04A Peripheral vasodilators

C04AA 2-amino-1-phenylethanol derivatives

:C04AA01

Isoxsuprine Isoxsuprine (used as isoxsuprine hydrochloride) is a drug used as a vasodilator in humans (under the trade name Duvadilan) and equines. Isoxsuprine is a β2 adrenoreceptor agonist that causes direct relaxation of uterine and vascular smooth musc ...

:C04AA02

Buphenine Buphenine (or nylidrin; trade name Arlidin) is a β2 adrenoreceptor agonist that acts as a vasodilator. It was developed as a chemical derivative of oxilofrine, and first reported in the literature in 1950. See also *Isoxsuprine Isoxsupri ...

:C04AA31

Bamethan Bamethan is a vasodilator Vasodilation is the widening of blood vessels. It results from relaxation of smooth muscle cells within the vessel walls, in particular in the large veins, large arteries, and smaller arterioles. The process is th ...

C04AB
Imidazoline Imidazoline is a class of heterocycles formally derived from imidazoles by the reduction of one of the two double bonds. Three isomers are known, 2-imidazolines, 3-imidazolines, and 4-imidazolines. The 2- and 3-imidazolines contain an imine In ...
derivatives

:C04AB01

Phentolamine Phentolamine, sold under the brand name Regitine among others, is a reversible nonselective α- adrenergic antagonist. Mechanism Its primary action is vasodilation due to α1 blockade. Non-selective α-blockers can cause a much more pronounced ...

:C04AB02

Tolazoline Tolazoline is a non-selective competitive α-adrenergic receptor antagonist. It is a vasodilator that is used to treat spasms of peripheral blood vessels (as in acrocyanosis). It has also been used (in conjunction with sodium nitroprusside) ...

C04AC Nicotinic acid and derivatives

:C04AC01 Nicotinic acid :C04AC02 Nicotinyl alcohol (pyridylcarbinol) :C04AC03 Inositol nicotinate :C04AC07 Ciclonicate

C04AD
Purine Purine is a heterocyclic compound, heterocyclic aromatic organic compound that consists of two rings (pyrimidine and imidazole) fused together. It is water-soluble. Purine also gives its name to the wider class of molecules, purines, which includ ...
derivatives

:C04AD01 Pentifylline :C04AD02 Xantinol nicotinate :C04AD03 Pentoxifylline :C04AD04 Etofylline nicotinate :QC04AD90 Propentofylline

C04AE Ergot alkaloids

:C04AE01 Ergoloid mesylates :C04AE02

Nicergoline Nicergoline, sold under the brand name Sermion among others, is an ergot derivative used to treat senile dementia and other disorders with vascular origins. Internationally it has been used for frontotemporal dementia as well as early onset in Le ...

:C04AE04 Dihydroergocristine :C04AE51 Ergoloid mesylates, combinations :C04AE54 Dihydroergocristine, combinations

C04AF
Enzyme Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
s

:C04AF01 Kallidinogenase

C04AX Other peripheral vasodilators

:C04AX01

Cyclandelate Cyclandelate is a vasodilator used in the treatment of claudication, arteriosclerosis Arteriosclerosis is the thickening, hardening, and loss of elasticity of the walls of arteries. This process gradually restricts the blood flow to one's or ...

:C04AX02

Phenoxybenzamine Phenoxybenzamine (marketed under the trade names Dibenzyline and Dibenyline) is a non-selective, irreversible alpha blocker. Uses It is used in the treatment of hypertension, and specifically that caused by pheochromocytoma. It has a slower ons ...

:C04AX07

Vincamine Vincamine is a monoterpenoid indole alkaloid found in the leaves of ''Vinca minor'' (lesser periwinkle), comprising about 25-65% of its indole alkaloids by weight. It can also be synthesized from related alkaloids. Uses Vincamine is sold in Eur ...

:C04AX10

Moxisylyte Moxisylyte, also known as thymoxamine, is a drug used in urology for the treatment of erectile dysfunction. It is an α1-adrenergic antagonist. In the United Kingdom, Moxisylte is marketed as Opilon (Archimedes Pharma UK Ltd) and is used for t ...

:C04AX11

Bencyclane Bencyclane is an antispasmodic, vasodilator, and platelet aggregation inhibitor. Synthesis Grignard addition of benzylmagnesiumbromide to suberone would give 1-benzylcycloheptanol 006-73-9(1'). Williamson ether synthesis with 3-dimethylamino ...

:C04AX17 Vinburnine :C04AX19 Sulcotidil :C04AX20

Buflomedil Buflomedil, sold under the brand name Loftyl, is a vasoactive drug used to treat claudication or the symptoms of peripheral arterial disease. It is currently not approved by the Food and Drug Administration (FDA) for use in the United States. T ...

:C04AX21 Naftidrofuryl :C04AX23

Butalamine Butalamine is a vasodilator. Synthesis Check with imolamine (alternate nitrogen reacts) The halogenation of benzamidoxime 32-90-1 22-31-1(1) with chlorine and subsequent reaction with cyanamide Cyanamide is an organic compound with the f ...

:C04AX24

Visnadine Visnadine (or visnadin) is a natural vasodilator. It was first isolated from bishop's weed Bishop's weed is a common name for several plants, all but one of which belong to the plant family Apiaceae. * ''Aegopodium podagraria'', which is an in ...

:C04AX26 Cetiedil :C04AX27 Cinepazide :C04AX28

Ifenprodil Ifenprodil is an inhibitor of the NMDA receptor, specifically of GluN1 (glycine-binding NMDA receptor subunit 1) and GluN2B (glutamate-binding NMDA receptor subunit 2) subunits. Additionally, ifenprodil inhibits GIRK channels, and interacts with a ...

:C04AX30 Azapetine :C04AX32

Fasudil Fasudil (INN) is a potent Rho-kinase inhibitor and vasodilator. Since it was discovered, it has been used for the treatment of cerebral vasospasm, which is often due to subarachnoid hemorrhage, as well as to improve the cognitive decline seen ...

References

{{Peripheral vasodilators C04