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8-hydroxyfuranocoumarin 8-O-methyltransferase
8-hydroxyfuranocoumarin 8-O-methyltransferase (, ''furanocoumarin 8-methyltransferase'', ''furanocoumarin 8-O-methyl-transferase'', ''xanthotoxol 8-O-methyltransferase'', ''XMT'', ''SAM:xanthotoxol O-methyltransferase'', ''S-adenosyl-L-methionine:8-hydroxyfuranocoumarin 8-O-methyltransferase'', ''xanthotoxol methyltransferase'', ''xanthotoxol O-methyltransferase'', ''S-adenosyl-L-methionine:xanthotoxol O-methyltransferase'', ''S-adenosyl-L-methionine-xanthotoxol O-methyltransferase'') is an enzyme with systematic name ''S-adenosyl-L-methionine:8-hydroxyfurocoumarin 8-O-methyltransferase''. This enzyme catalyses the following chemical reaction A chemical reaction is a process that leads to the IUPAC nomenclature for organic transformations, chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the pos ... : (1) S-adenosyl-L-methionine + an 8-hydroxyfurocoumarin \rightleftharpoons S-adenosyl-L-h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Xanthotoxol O-methyltransferase
8-hydroxyfuranocoumarin 8-O-methyltransferase (, ''furanocoumarin 8-methyltransferase'', ''furanocoumarin 8-O-methyl-transferase'', ''xanthotoxol 8-O-methyltransferase'', ''XMT'', ''SAM:xanthotoxol O-methyltransferase'', ''S-adenosyl-L-methionine:8-hydroxyfuranocoumarin 8-O-methyltransferase'', ''xanthotoxol methyltransferase'', ''xanthotoxol O-methyltransferase'', ''S-adenosyl-L-methionine:xanthotoxol O-methyltransferase'', ''S-adenosyl-L-methionine-xanthotoxol O-methyltransferase'') is an enzyme with List of enzymes, systematic name ''S-adenosyl-L-methionine:8-hydroxyfurocoumarin 8-O-methyltransferase''. This enzyme catalysis, catalyses the following chemical reaction : (1) S-adenosyl-L-methionine + an 8-hydroxyfurocoumarin \rightleftharpoons S-adenosyl-L-homocysteine + an 8-methoxyfurocoumarin (general reaction) : (2) S-adenosyl-L-methionine + xanthotoxol \rightleftharpoons S-adenosyl-L-homocysteine + xanthotoxin 8-hydroxyfuranocoumarin 8-O-methyltransferase converts xanthotoxol ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. Almost all metabolic processes in the cell need enzyme catalysis in order to occur at rates fast enough to sustain life. Metabolic pathways depend upon enzymes to catalyze individual steps. The study of enzymes is called ''enzymology'' and the field of pseudoenzyme analysis recognizes that during evolution, some enzymes have lost the ability to carry out biological catalysis, which is often reflected in their amino acid sequences and unusual 'pseudocatalytic' properties. Enzymes are known to catalyze more than 5,000 biochemical reaction types. Other biocatalysts are catalytic RNA molecules, called ribozymes. Enzymes' specificity comes from their unique three-dimensional structures. Like all catalysts, enzymes increase the reaction ra ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Enzymes
This article lists enzymes by their classification in the International Union of Biochemistry and Molecular Biology's Enzyme Commission (EC) numbering system. * List of EC numbers (EC 5) * List of EC numbers (EC 6) :Oxidoreductases (EC 1) (Oxidoreductase) *Dehydrogenase * Luciferase *DMSO reductase :EC 1.1 (act on the CH-OH group of donors) * :EC 1.1.1 (with NAD+ or NADP+ as acceptor) ** Alcohol dehydrogenase (NAD) ** Alcohol dehydrogenase (NADP) **Homoserine dehydrogenase ** Aminopropanol oxidoreductase **Diacetyl reductase **Glycerol dehydrogenase **Propanediol-phosphate dehydrogenase ** glycerol-3-phosphate dehydrogenase (NAD+) ** D-xylulose reductase **L-xylulose reductase **Lactate dehydrogenase **Malate dehydrogenase **Isocitrate dehydrogenase ** HMG-CoA reductase * :EC 1.1.2 (with a cytochrome as acceptor) * :EC 1.1.3 (with oxygen as acceptor) **Glucose oxidase **L-gulonolactone oxidase **Thiamine oxidase **Xanthine oxidase * :EC 1.1.4 (with a disul ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Catalysis
Catalysis () is the process of increasing the rate of a chemical reaction by adding a substance known as a catalyst (). Catalysts are not consumed in the reaction and remain unchanged after it. If the reaction is rapid and the catalyst recycles quickly, very small amounts of catalyst often suffice; mixing, surface area, and temperature are important factors in reaction rate. Catalysts generally react with one or more reactants to form intermediates that subsequently give the final reaction product, in the process of regenerating the catalyst. Catalysis may be classified as either homogeneous, whose components are dispersed in the same phase (usually gaseous or liquid) as the reactant, or heterogeneous, whose components are not in the same phase. Enzymes and other biocatalysts are often considered as a third category. Catalysis is ubiquitous in chemical industry of all kinds. Estimates are that 90% of all commercially produced chemical products involve catalysts at some s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemical Reaction
A chemical reaction is a process that leads to the IUPAC nomenclature for organic transformations, chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the positions of electrons in the forming and breaking of chemical bonds between atoms, with no change to the Atomic nucleus, nuclei (no change to the elements present), and can often be described by a chemical equation. Nuclear chemistry is a sub-discipline of chemistry that involves the chemical reactions of unstable and radioactive Chemical element, elements where both electronic and nuclear changes can occur. The substance (or substances) initially involved in a chemical reaction are called reagent, reactants or reagents. Chemical reactions are usually characterized by a chemical change, and they yield one or more Product (chemistry), products, which usually have properties different from the reactants. Reactions often consist of a sequence o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Xanthotoxol
Xanthotoxol is a furanocoumarin. It is one of the major active ingredients in ''Cnidium monnieri''.Xanthotoxol exerts neuroprotective effects via suppression of the inflammatory response in a rat model of focal cerebral ischemia. He W, Chen W, Zhou Y, Tian Y and Liao F, Cell Mol Neurobiol., July 2013, volume 33, issue 5, pages 715-722, Metabolism * Xanthotoxol O-methyltransferase ( 8-hydroxyfuranocoumarin 8-O-methyltransferase) is an enzyme that uses S-adenosyl methionine and xanthotoxol to produce S-adenosylhomocysteine and O-methylxanthotoxol (xanthotoxin or methoxsalen Methoxsalen, sold under the brand name Oxsoralen among others, is a medication used to treat psoriasis, eczema, vitiligo, and some cutaneous lymphomas in conjunction with exposing the skin to ultraviolet (UVA) light from lamps or sunlight. Methox ...). References Furanocoumarins Phenols {{aromatic-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Xanthotoxin
Methoxsalen, sold under the brand name Oxsoralen among others, is a medication used to treat psoriasis, eczema, vitiligo, and some cutaneous lymphomas in conjunction with exposing the skin to ultraviolet (UVA) light from lamps or sunlight. Methoxsalen modifies the way skin cells receive the UVA radiation, allegedly clearing up the disease. Levels of individual patient PUVA exposure were originally determined using the Fitzpatrick scale. The scale was developed after patients demonstrated symptoms of phototoxicity after oral ingestion of methoxsalen followed by PUVA therapy. Chemically, methoxsalen belongs to a class of organic natural molecules known as furanocoumarins. They consist of coumarin annulated with furan. It can also be injected and used topically. Natural sources In 1947, methoxsalen was isolated (under the name "ammoidin") from the plant ''Ammi majus'', bishop's weed. In 1970, Nielsen extracted 8-methoxypsoralen from four species of the genus '' Heracleum'' in the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
