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Étienne-Émile Baulieu
Étienne-Émile Baulieu (born 12 December 1926) is a French biochemist and endocrinologist who is best known for his research in the field of steroid hormones and their role in reproduction and aging. Biography Baulieu was born Émile Blum to Jewish parents in Strasbourg, France. His father, who died when he was four was Léon Blum, a physician, and an early specialist in diabetes. Baulieu changed his name during World War II when his family fled to the area near Grenoble and he engaged in the French resistance. After the war he attended the Faculté de Médecine de Paris and became a doctor of medicine in 1955. He studied further under his mentor Max Fernand Jayle in the field of steroid hormones and obtained his PhD degree in 1963 at the Lycée Pasteur, Faculté de Médecine and Faculté des Sciences in Paris. In 1963 Baulieu was named director of INSERM, and in 1970 he became a Professor of Biochemistry at the Faculty of Medicine of Bicêtre, affiliated with University o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Strasbourg
Strasbourg (, , ; german: Straßburg ; gsw, label=Bas Rhin Bas-Rhin (; Alsatian: ''Unterelsà ss'', ' or '; traditional german: links=no, Niederrhein; en, Lower Rhine) is a department in Alsace which is a part of the Grand Est super-region of France. The name means 'Lower Rhine', referring to its lowe ... Alsatian dialect, Alsatian, Strossburi , gsw, label=Haut Rhin Alsatian dialect, Alsatian, Strossburig ) is the Prefectures in France, prefecture and largest city of the Grand Est Regions of France, region of Geography of France, eastern France and the Seat of the European Parliament in Strasbourg, official seat of the European Parliament. Located at the France–Germany border, border with Germany in the historic region of Alsace, it is the prefecture of the Bas-Rhin Departments of France, department. In 2019, the city proper had 287,228 inhabitants and both the Eurométropole de Strasbourg (Greater Strasbourg) and the Arrondissement of Strasbourg had 505,272 inhabita ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Max Fernand Jayle
Max or MAX may refer to: Animals * Max (dog) (1983–2013), at one time purported to be the world's oldest living dog * Max (English Springer Spaniel), the first pet dog to win the PDSA Order of Merit (animal equivalent of OBE) * Max (gorilla) (1971–2004), a western lowland gorilla at the Johannesburg Zoo who was shot by a criminal in 1997 Brands and enterprises * Australian Max Beer * Max Hamburgers, a fast-food corporation * MAX Index, a Hungarian domestic government bond index * Max Fashion, an Indian clothing brand Computing * MAX (operating system), a Spanish-language Linux version * Max (software), a music programming language * Commodore MAX Machine * Multimedia Acceleration eXtensions, extensions for HP PA-RISC Films * ''Max'' (1994 film), a Canadian film by Charles Wilkinson * ''Max'' (2002 film), a film about Adolf Hitler * ''Max'' (2015 film), an American war drama film Games * ''Dancing Stage Max'', a 2005 game in the ''Dance Dance Revolution'' series * ''DDRM ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Seymour Lieberman
Seymour may refer to: Places Australia *Seymour, Victoria, a township * Electoral district of Seymour, a former electoral district in Victoria *Rural City of Seymour, a former local government area in Victoria *Seymour, Tasmania, a locality Canada * Seymour Range, a mountain range in British Columbia * Mount Seymour, British Columbia * Seymour River (Burrard Inlet), British Columbia * Seymour River (Shuswap Lake), British Columbia * Seymour Inlet, British Columbia * Seymour Narrows, British Columbia * Seymour Island (Nunavut) * Seymour Township, Ontario United States * Seymour, Connecticut, a town * Seymour, Illinois, a census-designated place * Seymour, Indiana, a city * Seymour, Iowa, a city * Seymour, Missouri, a city * Seymour, Tennessee, an unincorporated community and census-designated place * Seymour, Texas, a city * Seymour, Wisconsin (other) Elsewhere * Seymour Island, off the tip of Graham Land on the Antarctic Peninsula * Seymour, Eastern Cape, Sou ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Prohormone
A prohormone is a committed precursor of a hormone consisting of peptide hormones synthesized together that has a minimal hormonal effect by itself because of its expression-suppressing structure, often created by protein folding and binding additional peptide chains to certain ends, that makes hormone receptor binding sites located on its peptide hormone chain segments inaccessible. Prohormones can travel the blood stream as a hormone in an inactivated form, ready to be activated later in the cell by post-translational modification. The body naturally produces prohormones as a way to regulate hormone expression, making them an optimal storage and transportation unit for inactive hormones. Once prohormones are needed to be expressed, prohormone convertase, a protein, cleaves the prohormones and separates them into one or more active hormones. Often in nature, this cleaving process happens immediately, and a prohormone is quickly converted to a set of one or more peptide hormones. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Placenta
The placenta is a temporary embryonic and later fetal organ (anatomy), organ that begins embryonic development, developing from the blastocyst shortly after implantation (embryology), implantation. It plays critical roles in facilitating nutrient, gas and waste exchange between the physically separate maternal and fetal circulations, and is an important Endocrine system, endocrine organ, producing hormones that regulate both Maternal physiological changes in pregnancy, maternal and fetal physiology during pregnancy. The placenta connects to the fetus via the umbilical cord, and on the opposite aspect to the maternal uterus in a species-dependent manner. In humans, a thin layer of maternal decidual (Endometrium, endometrial) tissue comes away with the placenta when it is expelled from the uterus following birth (sometimes incorrectly referred to as the 'maternal part' of the placenta). Placentas are a defining characteristic of placental mammals, but are also found in marsupials an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Estrogen
Estrogen or oestrogen is a category of sex hormone responsible for the development and regulation of the female reproductive system and secondary sex characteristics. There are three major endogenous estrogens that have estrogenic hormonal activity: estrone (E1), estradiol (E2), and estriol (E3). Estradiol, an estrane, is the most potent and prevalent. Another estrogen called estetrol (E4) is produced only during pregnancy. Estrogens are synthesized in all vertebrates and some insects. Their presence in both vertebrates and insects suggests that estrogenic sex hormones have an ancient evolutionary history. Quantitatively, estrogens circulate at lower levels than androgens in both men and women. While estrogen levels are significantly lower in males than in females, estrogens nevertheless have important physiological roles in males. Like all steroid hormones, estrogens readily diffuse across the cell membrane. Once inside the cell, they bind to and activate estrogen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sulfate
The sulfate or sulphate ion is a polyatomic ion, polyatomic anion with the empirical formula . Salts, acid derivatives, and peroxides of sulfate are widely used in industry. Sulfates occur widely in everyday life. Sulfates are salt (chemistry), salts of sulfuric acid and many are prepared from that acid. Spelling "Sulfate" is the spelling recommended by International Union of Pure and Applied Chemistry, IUPAC, but "sulphate" was traditionally used in British English. Structure The sulfate anion consists of a central sulfur atom surrounded by four equivalent oxygen atoms in a tetrahedron, tetrahedral arrangement. The symmetry is the same as that of methane. The sulfur atom is in the +6 oxidation state while the four oxygen atoms are each in the −2 state. The sulfate ion carries an overall charge (physics), charge of −2 and it is the conjugate acid, conjugate base of the bisulfate (or hydrogensulfate) ion, , which is in turn the conjugate base of , sulfuric acid. Organic sulf ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Androgen
An androgen (from Greek ''andr-'', the stem of the word meaning "man") is any natural or synthetic steroid hormone that regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors. This includes the embryological development of the primary male sex organs, and the development of male secondary sex characteristics at puberty. Androgens are synthesized in the testes, the ovaries, and the adrenal glands. Androgens increase in both males and females during puberty. The major androgen in males is testosterone. Dihydrotestosterone (DHT) and androstenedione are of equal importance in male development. DHT ''in utero'' causes differentiation of the penis, scrotum and prostate. In adulthood, DHT contributes to balding, prostate growth, and sebaceous gland activity. Although androgens are commonly thought of only as male sex hormones, females also have them, but at lower levels: they function in libido and sexual arousal. Al ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adrenal Gland
The adrenal glands (also known as suprarenal glands) are endocrine glands that produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol. They are found above the kidneys. Each gland has an outer cortex which produces steroid hormones and an inner medulla. The adrenal cortex itself is divided into three main zones: the zona glomerulosa, the zona fasciculata and the zona reticularis. The adrenal cortex produces three main types of steroid hormones: mineralocorticoids, glucocorticoids, and androgens. Mineralocorticoids (such as aldosterone) produced in the zona glomerulosa help in the regulation of blood pressure and electrolyte balance. The glucocorticoids cortisol and cortisone are synthesized in the zona fasciculata; their functions include the regulation of metabolism and immune system suppression. The innermost layer of the cortex, the zona reticularis, produces androgens that are converted to fully functional sex hormones i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Longevity
The word " longevity" is sometimes used as a synonym for "life expectancy" in demography. However, the term ''longevity'' is sometimes meant to refer only to especially long-lived members of a population, whereas ''life expectancy'' is always defined statistically as the average number of years remaining at a given age. For example, a population's life expectancy at birth is the same as the average age at death for all people born in the same year (in the case of cohorts). Longevity is best thought of as a term for general audiences meaning 'typical length of life' and specific statistical definitions should be clarified when necessary. Reflections on longevity have usually gone beyond acknowledging the brevity of human life and have included thinking about methods to extend life. Longevity has been a topic not only for the scientific community but also for writers of travel, science fiction, and utopian novels. In fact the legendary fountain of youth appeared in the work of th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Paris
The University of Paris (french: link=no, Université de Paris), Metonymy, metonymically known as the Sorbonne (), was the leading university in Paris, France, active from 1150 to 1970, with the exception between 1793 and 1806 under the French Revolution. Emerging around 1150 as a corporation associated with the cathedral school of Notre Dame de Paris, it was considered the List of medieval universities, second-oldest university in Europe.Charles Homer Haskins, Haskins, C. H.: ''The Rise of Universities'', Henry Holt and Company, 1923, p. 292. Officially chartered in 1200 by King Philip II of France and recognised in 1215 by Pope Innocent III, it was later often nicknamed after its theological College of Sorbonne, in turn founded by Robert de Sorbon and chartered by List of French monarchs, French King Louis IX, Saint Louis around 1257. Internationally highly reputed for its academic performance in the humanities ever since the Middle Ages – notably in theology and philosophy – ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
