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Élie Metchnikoff
Ilya Ilyich Mechnikov (russian: Илья Ильич Мечников; – 15 July 1916), also spelled Élie Metchnikoff, was a Russian zoologist best known for his pioneering research in immunology. Belkin, a Russian science historian, explains why Metchnikoff himself, in his Nobel autobiography – and subsequently, many other sources – mistakenly cited his date of birth as 16 May instead of 15 May. Metchnikoff made the mistake of adding 13 days to 3 May, his Old Style birthday, as was the convention in the 20th century. But since he had been born in the 19th century, only 12 days should have been added. He and Paul Ehrlich were jointly awarded the 1908 Nobel Prize in Physiology or Medicine "in recognition of their work on immunity". Mechnikov was born in modern-day Ukraine to a Romanian noble father and a Ukrainian-Jewish mother, lived and worked for many years on the territory of what was then the Russian Empire, and later on continued his career in France. Given this com ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kharkov Governorate
The Kharkov Governorate ( pre-reform Russian: , tr. ''Khárkovskaya gubérniya'', IPA: xarʲkəfskəjə ɡʊˈbʲernʲɪjə ) was a governorate of the Russian Empire founded in 1835. It embraced the historical region of Sloboda Ukraine. From 1765 to 1780 and from 1796 to 1835 the governorate was called the Sloboda Ukraine Governorate. In 1780-1796 there existed the Kharkov Viceroyalty. From 1765 to 1780, the Sloboda–Ukraine Governorate existed. In 1780, the Kharkov Viceroyalty was established and lasted until 1796. In 1835, the Viceroyalty was again reorganized into the Sloboda-Ukrainian Governorate, and from 1835 onwards, the Kharkov Governorate was formed, which existed until 1925. With each reorganization, the boundaries and administrative structure change significantly. The main state tax implementation, processing, and publishing of statistical information for the Kharkov governorate were the Kharkov Governorate Statistical Committee. History Slobozhanshchyna, with ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Albert Medal (Royal Society Of Arts)
The Albert Medal of the Royal Society of Arts (RSA) was instituted in 1864 as a memorial to Prince Albert, who had been President of the Society for 18 years. It was first awarded in 1864 for "distinguished merit in promoting Arts, Manufactures and Commerce". In presenting the Medal, the Society now looks to acknowledge individuals, organizations and groups that lead progress and create positive change within contemporary society in areas that are linked closely to the Society's broad agenda. Through the Albert Medal, the Society acknowledges the creativity and innovation of those that work to tackle some of the world's intractable problems. Each year, the RSA identifies issues by asking the Society's Fellowship to suggest problems and subjects linked to the Society's programme. These proposals are reviewed and recommendations made to the Trustees and Council, who are responsible for selecting one upon which the Fellowship will be asked to nominate worthy recipients. Full list ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Humoral Immunity
Humoral immunity is the aspect of immunity that is mediated by macromolecules - including secreted antibodies, complement proteins, and certain antimicrobial peptides - located in extracellular fluids. Humoral immunity is named so because it involves substances found in the humors, or body fluids. It contrasts with cell-mediated immunity. Humoral immunity is also referred to as antibody-mediated immunity. The study of the molecular and cellular components that form the immune system, including their function and interaction, is the central science of immunology. The immune system is divided into a more primitive innate immune system and an acquired or adaptive immune system of vertebrates, each of which contain both humoral and cellular immune elements. Humoral immunity refers to antibody production and the coinciding processes that accompany it, including: Th2 activation and cytokine production, germinal center formation and isotype switching, and affinity maturation an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Macrophage
Macrophages (abbreviated as M φ, MΦ or MP) ( el, large eaters, from Greek ''μακρός'' (') = large, ''φαγεῖν'' (') = to eat) are a type of white blood cell of the immune system that engulfs and digests pathogens, such as cancer cells, microbes, cellular debris, and foreign substances, which do not have proteins that are specific to healthy body cells on their surface. The process is called phagocytosis, which acts to defend the host against infection and injury. These large phagocytes are found in essentially all tissues, where they patrol for potential pathogens by amoeboid movement. They take various forms (with various names) throughout the body (e.g., histiocytes, Kupffer cells, alveolar macrophages, microglia, and others), but all are part of the mononuclear phagocyte system. Besides phagocytosis, they play a critical role in nonspecific defense (innate immunity) and also help initiate specific defense mechanisms (adaptive immunity) by recruiting other immune ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phagocyte
Phagocytes are cells that protect the body by ingesting harmful foreign particles, bacteria, and dead or dying cells. Their name comes from the Greek ', "to eat" or "devour", and "-cyte", the suffix in biology denoting "cell", from the Greek ''kutos'', "hollow vessel". They are essential for fighting infections and for subsequent immunity. Phagocytes are important throughout the animal kingdom and are highly developed within vertebrates. One litre of human blood contains about six billion phagocytes. They were discovered in 1882 by Ilya Ilyich Mechnikov while he was studying starfish larvae.Ilya Mechnikov retrieved on November 28, 2008. Fro ''Physiology or Medicine 1901–1921'' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phagocytosis
Phagocytosis () is the process by which a cell uses its plasma membrane to engulf a large particle (≥ 0.5 μm), giving rise to an internal compartment called the phagosome. It is one type of endocytosis. A cell that performs phagocytosis is called a phagocyte. In a multicellular organism's immune system, phagocytosis is a major mechanism used to remove pathogens and cell debris. The ingested material is then digested in the phagosome. Bacteria, dead tissue cells, and small mineral particles are all examples of objects that may be phagocytized. Some protozoa use phagocytosis as means to obtain nutrients. History Phagocytosis was first noted by Canadian physician William Osler (1876), and later studied and named by Élie Metchnikoff (1880, 1883). In immune system Phagocytosis is one main mechanisms of the innate immune defense. It is one of the first processes responding to infection, and is also one of the initiating branches of an adaptive immune response. Although mo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Innate Immunity
The innate, or nonspecific, immune system is one of the two main immunity strategies (the other being the adaptive immune system) in vertebrates. The innate immune system is an older evolutionary defense strategy, relatively speaking, and is the dominant immune system response found in plants, fungi, insects, and primitive multicellular organisms (see Beyond vertebrates).. The major functions of the innate immune system are to: * recruit immune cells to infection sites by producing chemical factors, including chemical mediators called cytokines * activate the complement cascade to identify bacteria, activate cells, and promote clearance of antibody complexes or dead cells * identify and remove foreign substances present in organs, tissues, blood and lymph, by specialized white blood cells * activate the adaptive immune system through antigen presentation * act as a physical and chemical barrier to infectious agents; via physical measures such as skin and chemical measures such ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Atheism
Atheism, in the broadest sense, is an absence of belief in the existence of deities. Less broadly, atheism is a rejection of the belief that any deities exist. In an even narrower sense, atheism is specifically the position that there no deities. Atheism is contrasted with theism, which in its most general form is the belief that at least one deity exists. The first individuals to identify themselves as atheists lived in the 18th century during the Age of Enlightenment. The French Revolution, noted for its "unprecedented atheism", witnessed the first significant political movement in history to advocate for the supremacy of human reason.Extract of page 22 In 1967, Albania declared itself the first official atheist coun ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Russian Orthodox Church
, native_name_lang = ru , image = Moscow July 2011-7a.jpg , imagewidth = , alt = , caption = Cathedral of Christ the Saviour in Moscow, Russia , abbreviation = ROC , type = , main_classification = Eastern Orthodox , orientation = Russian Orthodoxy , scripture = Elizabeth Bible ( Church Slavonic) Synodal Bible (Russian) , theology = Eastern Orthodox theology , polity = Episcopal , governance = Holy Synod of the Russian Orthodox Church , structure = Communion , leader_title = , leader_name = , leader_title1 = Primate , leader_name1 = Patriarch Kirill of Moscow , leader_title2 = , leader_name2 = , leader_title3 = Bishops , leader_name3 = 382 (2019) , fellowships_type = Clergy , fellowships = 40,514 full-time clerics, including 35,677 presbyters and 4,837 de ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bloomsbury Publishing
Bloomsbury Publishing plc is a British worldwide publishing house of fiction and non-fiction. It is a constituent of the FTSE SmallCap Index. Bloomsbury's head office is located in Bloomsbury, an area of the London Borough of Camden. It has a US publishing office located in New York City, an India publishing office in New Delhi, an Australia sales office in Sydney CBD and other publishing offices in the UK including in Oxford. The company's growth over the past two decades is primarily attributable to the ''Harry Potter'' series by J. K. Rowling and, from 2008, to the development of its academic and professional publishing division. The Bloomsbury Academic & Professional division won the Bookseller Industry Award for Academic, Educational & Professional Publisher of the Year in both 2013 and 2014. Divisions Bloomsbury Publishing group has two separate publishing divisions—the Consumer division and the Non-Consumer division—supported by group functions, namely Sales and Mar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ukrainian-Jewish
The history of the Jews in Ukraine dates back over a thousand years; Jewish communities have existed in the territory of Ukraine from the time of the Kievan Rus' (late 9th to mid-13th century). Some of the most important Jewish religious and cultural movements, from Hasidism to Zionism, rose either fully or to an extensive degree in the territory of modern Ukraine. According to the World Jewish Congress, the Jewish community in Ukraine constitutes the third-largest in Europe and the fifth-largest in the world. The actions of the Soviet government by 1927 led to a growing antisemitism in the area.Сергійчук, В. Український Крим К. 2001, p.156 Total civilian losses during World War II and the Reichskommissariat Ukraine, German occupation of Ukraine are estimated at seven million. More than one million Soviet Jews, of them around 225,000 in Belarus, were shot and killed by the Einsatzgruppen and by their many local Ukrainian supporters. Most of them were ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Romanian Nobility
The boyars of Moldavia and Wallachia were the nobility of the Danubian Principalities of Moldavia and Wallachia. The title was either inherited or granted by the Hospodar, often together with an administrative function.Djuvara, p.131 The boyars held much of the political power in the principalities and, until the Phanariote era, they elected the Hospodar. As such, until the 19th century, the system oscillated between an oligarchy and an autocracy with the power concentrated in the hospodar's hands.Djuvara, p.135 Origins During the Middle Ages, Romanians lived in autonomous communities called obște which mixed private and common ownership, employing an open field system. The private ownership of land gained ground In the 14th and 15th centuries, leading to differences within the obște towards a stratification of the members of the community.Costăchel et al., p. 111 The name of the "boyars" (''boier'' in Romanian; the institution being called ''boierie'') was patented from the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
