Topic summary

Zolmitriptan

Zolmitriptan

Zolmitriptan, sold under the brand name Zomig among others, is a serotonergicmedication which is used in the acute treatment of migraine attacks with or without aura and cluster headaches. It is taken by mouth as a swallowed or disintegratingtablet or as a nasal spray.

Side effects include tightness in the neck or throat, jaw pain, dizziness, paresthesia, asthenia, somnolence, warm/cold sensations, nausea, chest pressure, and dry mouth. The drug acts as a selectiveserotonin5-HT1B and 5-HT1D receptoragonist. Structurally, it is a triptan and a tryptaminederivative.

It was patented in 1990 and was approved for medical use in 1997.