Viriform

Viriforms

Viriforms are a polyphyletic category of endogenous viral elements. Sometime in their evolution, they became "domesticated" by their host as a key part of the host's lifecycle. The prototypical example is members of the (also polyphyletic) Polydnaviriformidae, which are used by wasps to send pieces of immunity-blunting DNA into the prey by packing them into virion-like particles. Other members are so-called gene transfer agents (GTAs) found among prokaryotes. GTA particles resemble tailed phages, but are smaller and carry mostly random pieces of host DNA. GTAs are produced by the host in times of stress; releasing GTAs kills the host cell, but allows pieces of its genetic material to live on in other bacteria, usually of the same species. The three known clades of GTAs, Rhodogtaviriformidae, Bartogtaviriformidae, and Brachygtaviriformidae, all arose independently from different parts of the Caudoviricetes family tree.