Thessalonica

Byzantine era and Middle Ages

Thessalonica remained in Ottoman hands until 1403, when Emperor Manuel II sided with Bayezid's eldest son Süleyman in the Ottoman succession struggle that broke out following the crushing defeat and capture of Bayezid at the Battle of Ankara against Tamerlane in 1402. In exchange for his support, in the Treaty of Gallipoli the Byzantine emperor secured the return of Thessalonica, part of its hinterland, the Chalcidice peninsula, and the coastal region between the rivers Strymon and Pineios. Thessalonica and the surrounding region were given as an autonomous appanage to John VII Palaiologos. After his death in 1408, he was succeeded by Manuel's third son, the DespotAndronikos Palaiologos, who was supervised by Demetrios Leontares until 1415.