Separase

More reference expression dataBioGPSEnsemblUniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)Chr 12: 53.27 – 53.29 MbChr 15: 102.2 – 102.23 MbPubMed searchWikidata

Separase, also known as separin, is a cysteineprotease responsible for triggering anaphase by hydrolysing cohesin, which is the protein responsible for binding sister chromatids during the early stage of anaphase. In humans, separin is encoded by the ESPL1gene.