SN-22

SN-22 is a piperidinylindole which acts as a moderately selectiveagonist at the 5-HT₂ family of serotoninreceptors, with a K_i of 19 nM at 5-HT₂ subtypes versus 514 nM at 5-HT_1A receptors. Many related derivatives are known, most of which are ligands for 5-HT_1A, 5-HT₆ or dopamine D₂ receptors or show SSRI activity.