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Topic summary

Roxarsone

Roxarsone
Names Preferred IUPAC name
(4-Hydroxy-3-nitrophenyl)arsonic acid
Identifiers
3D model (JSmol)
1976533 ChEBI
ChEMBL
ChemSpider
ECHA InfoCard100.004.049EC Number
  • 204-453-7
1221211 KEGG
MeSHRoxarsone
RTECS number
  • CY5250000
UNII
UN number3465
  • InChI=1S/C6H6AsNO6/c9-6-2-1-4(7(10,11)12)3-5(6)8(13)14/h1-3,9H,(H2,10,11,12)
    Key: XMVJITFPVVRMHC-UHFFFAOYSA-N
  • InChI=1/C6H6AsNO6/c9-6-2-1-4(7(10,11)12)3-5(6)8(13)14/h1-3,9H,(H2,10,11,12)
    Key: XMVJITFPVVRMHC-UHFFFAOYAF
  • Oc1ccc(cc1[N+](=O)[O-])[As](O)(O)=O
  • OC1=CC=C(C=C1[N+]([O-])=O)[As](O)(O)=O
Properties C
6AsNH
6O
6Molar mass263.0365 g mol Melting point> 300 °C (572 °F; 573 K) Hazards GHS labelling: DangerH301, H331, H410P261, P273, P301+P310, P311, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Roxarsone is an organoarsenic compound that has been used in poultry production and to a lesser extent in pig production as a feed additive to increase weight gain, for greater feed efficiency, to improve pigmentation, and as a coccidiostat. Until June 2011, it was approved for use in the United States, Canada, Australia, and 12 other countries. It is no longer approved for use in most jurisdictions.

Roxarsone has been banned in the European Union since 1999. Its use in the United States was voluntarily ended by the manufacturers in June 2011, and it has been illegal since 2013. Its use was suspended in Malaysia in June 2011. It was banned in Canada in August 2011. In Australia, its use was discontinued in 2012.

Wikipedia source