Oxitriptan

Oxitriptan, also known as L-5-hydroxytryptophan (5-HTP) and sold under various brand names, is a medication and over-the-counterdietary supplement used in the treatment of depression and for other indications. It is taken by mouth.

Side effects of oxitriptan include appetite loss, nausea, diarrhea, vomiting, and serotonin syndrome. The drug is a centrallypermeablemonoamine precursor and prodrug of serotonin and hence acts as a serotonin receptor agonist. Chemically, oxitriptan is an amino acid and a tryptamine.

Oxitriptan has been used clinically since at least the 1970s.