Topic summary
Mycolactone

Mycolactone is a polyketide-derived macrolide produced and secreted by a group of very closely related pathogenicmycobacteria species including M. ulcerans, (an unofficial designation), , and some strains of M. marinum. These mycobacteria are collectively referred to as mycolactone-producing mycobacteria or MPM.
In humans, mycolactone is the toxin responsible for Buruli ulcers, doing so by damaging tissues and inhibiting the immune response.