Topic summary

LLGL1

LLGL1
More reference expression dataBioGPSEnsemblUniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)Chr 17: 18.23 – 18.24 MbChr 11: 60.59 – 60.61 MbPubMed searchWikidata

Lethal(2) giant larvae protein homolog 1 is a protein that in humans is encoded by the LLGL1gene.

This gene encodes a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene is located within the Smith-Magenis syndrome region on chromosome 17.