Topic summary
ILC3
Extracted from the Wikipedia article Type 3 innate lymphoid cells.
ILC3 cells in disease
ILC3 cells have in recent years also been linked to immune responses to fungal pathogen Candida albicans. This opportunistic pathogen induces Th17 immune response. This is supported by the fact that ILC3 cells mirror the phenotype of Th17 cells, and a subset of ILC3 cells has also been recently observed to have potent antigen presenting properties. ILC3s contribute in immune response to this pathogen by mediating the immune response via secretion of cytokines such as IL-17A.